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How to get fromFishers to St. Louisby bus (Greyhound), car, taxi, or plane

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There are 3 ways to get from Fishers to St. Louis by bus (Greyhound), car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    4h 21m
    $88–121

  2. Drive  257.4 mi

    cheapest
    1. Drive from Fishers to St. Louiscar car 257.4 mi
    4h 25m
    $44–64

  3. Taxi, fly

    1. Take the taxi from Fishers to Indianapolis-Airport-INDtaxi taxi
    2. Fly from Indianapolis (IND) to Lambert–St. Louis International Airport (STL)plane plane IND - STL
    4h 51m
    $168–686

Indianapolis (IND) to Lambert–St. Louis International Airport (STL) flights

Calendar134Weekly Planes
Duration4h 19mAverage Duration
Ticket$95Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fishers to St. Louis.ExpandLaunch map view
  • Distance: 259 mi
  • Duration: 4h 21m

What companies run services between Fishers, IN, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Indianapolis Union Station to St Louis Bus Station every 4 hours. Tickets cost $45–70 and the journey takes 3h 55m.

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