There are 8 ways to get from Estero to Murrells Inlet by bus, plane, train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Tampa, fly to Myrtle Beach
best- Take the bus from Fort Myers 7-11 to Tampa International Airport
- Fly from Tampa (TPA) to Myrtle Beach (MYR)TPA - MYR
5h 42m$194–461Drive 623.1 mi
cheapest- Drive from Estero to Murrells Inlet623.1 mi
11h 27m$114–165Bus, train, drive
- Take the bus from Naples to Fort Lauderdale
- Take the train from Fort Lauderdale Amtrak Station to Kingstree Amtrak Station
- Drive from Kingstree Amtrak Station to Murrells Inlet
19h 3m$162–283Bus
- Take the bus from Fort Myers Bus Stop to Orlando Bus Station
- Take the bus from Orlando Bus Station to Florence Bus Station
- Take the bus from Florence Bus Station to Myrtle Beach Bus Station
20h 52m$152–331Fly Ft. Myers to Myrtle Beach
- Fly from Ft. Myers (RSW) to Myrtle Beach (MYR)RSW - MYR
7h 19m$194–435Bus to Fort Lauderdale–Hollywood International Airport, fly to Myrtle Beach
- Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airport
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)FLL - MYR
7h 42m$142–311Fly Ft. Myers to Wilmington International Airport, bus
- Fly from Ft. Myers (RSW) to Wilmington International Airport (ILM)RSW - ILM
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
7h 58m$188–560Bus, train
- Take the bus from Fort Myers Bus Stop to Orlando
- Take the train from Kissimmee Amtrak Station to Charleston Amtrak Station
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Station
22h 1m$178–323
Tampa (TPA) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Estero to Murrells Inlet is to drive which costs $110 - $170 and takes 11h 27m.
The fastest way to get from Estero to Murrells Inlet is to bus and fly which takes 5h 42m and costs $190 - $470.
The distance between Estero and Murrells Inlet is 616 miles. The road distance is 626.7 miles.
The best way to get from Estero to Murrells Inlet without a car is to bus which takes 20h 52m and costs $150 - $340.
It takes approximately 5h 42m to get from Estero to Murrells Inlet, including transfers.
The best way to get from Estero to Murrells Inlet is to bus which takes 20h 52m and costs $150 - $340. Alternatively, you can fly, which costs $190 - $440 and takes 7h 19m.
Yes, the driving distance between Estero to Murrells Inlet is 627 miles. It takes approximately 11h 27m to drive from Estero to Murrells Inlet.
There are 2692+ hotels available in Murrells Inlet.
What companies run services between Estero, FL, USA and Murrells Inlet, SC, USA?
You can take a bus from S Tamiami Trl @ County Rd to Murrells Inlet via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Orlando Bus Station, Florence Bus Station, and Myrtle Beach Bus Station in around 20h 52m. Alternatively, American Airlines, Delta, and Southwest Airlines fly from Ft. Myers (RSW) to Myrtle Beach (MYR) every 3 hours.
- Website
- aa.com
Flights from Tampa to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $55–330
Flights from Ft. Myers to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $80–460
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $50–280
Flights from Ft. Myers to Wilmington International Airport via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $85–480
- Website
- delta.com
Flights from Tampa to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 51m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $60–340
Flights from Ft. Myers to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $85–470
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $50–290
Flights from Ft. Myers to Wilmington International Airport via Atlanta
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $90–500
- Website
- southwest.com
Flights from Ft. Myers to Myrtle Beach via Nashville
- Ave. Duration
- 6h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Ft. Myers to Myrtle Beach via Baltimore
- Ave. Duration
- 5h 12m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $110–600
- Website
- flybreeze.com
Flights from Tampa to Myrtle Beach
- Ave. Duration
- 1h 34m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $170–260
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach
- Ave. Duration
- 1h 45m
- When
- Monday and Friday
- Estimated price
- $100–460
Flights from Ft. Myers to Wilmington International Airport
- Ave. Duration
- 1h 55m
- When
- Monday and Friday
- Estimated price
- $180–800
- Website
- spirit.com
Flights from Tampa to Myrtle Beach via Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- $100–300
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $75–200
- Website
- aveloair.com
Flights from Ft. Myers to Wilmington International Airport
- Ave. Duration
- 1h 52m
- When
- Monday and Friday
- Estimated price
- $140–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fort Lauderdale Amtrak Station to Kingstree Amtrak Station
- Ave. Duration
- 13h 35m
- Frequency
- Once daily
- Estimated price
- $85–140
- Website
- https://www.amtrak.com/home.html
Train from Kissimmee Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 8h 28m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Myers 7-11 to Tampa International Airport
- Ave. Duration
- 2h 20m
- Frequency
- 5 times a week
- Estimated price
- $15–65
- Website
- https://www.redcoachusa.com
- Web
- $15–65
Bus from Naples to Fort Lauderdale
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $13–60
- Website
- https://www.redcoachusa.com
- Web
- $13–60
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Fort Myers Bus Stop to Orlando Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- 5 times a day
- Estimated price
- $28–45
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Florence Bus Station
- Ave. Duration
- 9h 35m
- Frequency
- Once daily
- Estimated price
- $60–130
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Fort Lauderdale International Airport
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $25–35
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Orlando
- Ave. Duration
- 5h 50m
- Frequency
- 3 times a day
- Estimated price
- $29–60
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $16–19
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $16–22
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
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