Rome2Rio

How to get fromEstero to Key Largoby bus (Greyhound), car, plane, shuttle, bus (Flixbus, Greyhound), bus or train

Find Transport to Key Largo

See all options

There are 8 ways to get from Estero to Key Largo by bus (Greyhound), car, plane, shuttle, bus (Flixbus, Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Golden Gate

    best
    1. Take the bus from Naples, FL to Fort Lauderdale Airportbus bus Tampa
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    6h 2m
    $91–229

  2. Drive 162.9 mi

    cheapest
    1. Drive from Estero to Key Largocar car 162.9 mi
    3h 19m
    $30–43

  3. Fly Ft. Myers to Miami International Airport, shuttle

    1. Fly from Ft. Myers (RSW) to Miami International Airport (MIA)plane plane RSW - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    8h 15m
    $138–475

  4. Bus

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    7h 53m
    $42–83

  5. Bus #2

    1. Take the bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    8h 40m
    $42–79

  6. Line 240 bus, line 140 bus, bus, line 2600 train, line 38 bus

    1. Take the bus from S Tamiami Trl @ County Rd to South Fort Myers Transfer/P&Rbus bus 140 / ...
    2. Take the bus from South Fort Myers Transfer/P&R to Rosa Parks Transportation Ctrbus bus 140
    3. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    4. Take the train from Miami Airport Station to Dadeland South Stat.Rail Southboundtrain train
    5. Take the bus from Dadeland South Metrorail Station to SW 344 St @ Park & Ridebus bus 38 / ...
    6. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    8h 54m

  7. Bus to Tampa, fly to Miami International Airport, shuttle

    1. Take the bus from Fort Myers 7-11 to Tampa International Airportbus bus
    2. Fly from Tampa (TPA) to Miami International Airport (MIA)plane plane TPA - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    7h 6m
    $237–666

  8. Bus to Tampa, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the bus from Fort Myers 7-11 to Tampa International Airportbus bus
    2. Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TPA - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    7h 36m
    $197–436

Estero to Key Largo by bus

Calendar19Weekly Buses
Duration7h 53mAverage Duration
Ticket$42Cheapest Price
See schedules

Questions & Answers

What companies run services between Estero, FL, USA and Key Largo, FL, USA?

You can take a vehicle from Estero to Key Largo Bus Stop via Naples, FL, Terminal 2/3, Tri-Rail FLL Airport Station, Fort Lauderdale Airport Station, Miami, Airport Intermodal Station, and Miami Airport Station in around 6h 2m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Estero

Trips to Key Largo

Popular routes