There are 3 ways to get from Estero to Florida Keys by ferry, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry
best- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
6h 20m$168–179Drive 244.6 mi
cheapest- Drive from Estero to Florida Keyscar 244.6 mi
5h 12m$45–65Bus
- Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus FlixBus 2421
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
11h 28m$50–79
Questions & Answers
The cheapest way to get from Estero to Florida Keys is to drive which costs $40 - $65 and takes 5h 12m.
The fastest way to get from Estero to Florida Keys is to drive which takes 5h 12m and costs $40 - $65.
No, there is no direct bus from Estero to Florida Keys. However, there are services departing from S Tamiami Trl @ County Rd and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 11h 28m.
The distance between Estero and Florida Keys is 172 miles. The road distance is 246 miles.
The best way to get from Estero to Florida Keys without a car is to ferry which takes 6h 20m and costs $160 - $180.
It takes approximately 6h 20m to get from Estero to Florida Keys, including transfers.
Estero to Florida Keys bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Estero to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Estero to Florida Keys is 246 miles. It takes approximately 5h 12m to drive from Estero to Florida Keys.
There are 943+ hotels available in Florida Keys.
What companies run services between Estero, FL, USA and Florida Keys, FL, USA?
Key West Express operates a ferry from Fort Myers Beach, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a bus from S Tamiami Trl @ County Rd to Florida Keys via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 11h 28m.
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Fort Myers Bus Stop to Miami Airport Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $25–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–29
- Website
- https://www.greyhound.com/
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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