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How to get fromEstero to Florida Keysby ferry, bus (Flixbus, Greyhound) or car

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There are 3 ways to get from Estero to Florida Keys by ferry, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry

    best
    1. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    6h 20m
    $168–179
  2. Drive 244.6 mi

    cheapest
    1. Drive from Estero to Florida Keyscar car 244.6 mi
    5h 12m
    $45–65
  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    11h 28m
    $50–79

Questions & Answers

What companies run services between Estero, FL, USA and Florida Keys, FL, USA?

Key West Express operates a ferry from Fort Myers Beach, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a bus from S Tamiami Trl @ County Rd to Florida Keys via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 11h 28m.

Bus operators
Ferry operators

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