Rome2Rio

How to get fromErie to St. Louisby plane, train (Amtrak), bus (Greyhound), car, train or bus

Find Transport to St. Louis

See all options

There are 7 ways to get from Erie to St. Louis by plane, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Erie International Airport

    best
    1. Fly from Erie International Airport (ERI) to Lambert–St. Louis International Airport (STL)plane plane ERI - STL
    7h 3m
    $105–605

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Erie to Pittsburgh Intermodal Stationbus bus Greyhound US0440s
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    17h 25m
    $86–210

  3. Train (Amtrak)

    1. Take the train from Erie Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    14h 42m
    $92–394

  4. Drive 648.6 mi

    1. Drive from Erie to St. Louiscar car 648.6 mi
    10h 58m
    $119–171

  5. Train to Cleveland-Hopkins International Airport, fly

    1. Take the train from Erie Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    6h 12m
    $198–463

  6. Bus to Pittsburgh International Airport, fly

    1. Take the bus from Erie to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    8h 56m
    $139–743

  7. Train, bus

    1. Take the train from Erie Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus N2521 / ...
    16h 15m
    $92–244

Erie to St. Louis by train (Amtrak)

Calendar14Weekly Trains
Duration14h 42mAverage Duration
Ticket$92Cheapest Price
See schedules

Questions & Answers

What companies run services between Erie, PA, USA and St. Louis, MO, USA?

United Airlines, American Airlines, and two other airlines fly from Erie International Airport (ERI) to Lambert–St. Louis International Airport (STL) 3 times a day. Alternatively, you can take a train from Erie Station to St. Louis via Chicago Union Station in around 14h 42m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Erie

Trips to St. Louis

Popular routes