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How to get fromEnola to Chicagoby bus, plane, train (Amtrak), bus (Flixbus), car, train or bus (Greyhound)

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There are 7 ways to get from Enola to Chicago by bus, plane, train (Amtrak), bus (Flixbus), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Harrisburg International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from Enola Dr & Cumberland Rd to Market Square Transfer Centerbus bus
    2. Fly from Harrisburg International Airport (MDT) to Chicago O'Hare International Airport (ORD)plane plane MDT - ORD
    5h 50m
    $49–299

  2. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train Pennsylvanian
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    17h 28m
    $105–247

  3. Bus (Flixbus)

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640
    17h 43m
    $80–192

  4. Drive 652.6 mi

    1. Drive from Enola to Chicagocar car 652.6 mi
    10h 42m
    $120–172

  5. Bus to Penn State University Park Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Harrisburg Bus Station to State College Regional Airportbus bus
    2. Fly from Penn State University Park Airport (SCE) to Chicago O'Hare International Airport (ORD)plane plane SCE - ORD
    6h 52m
    $72–417

  6. Train to Philadelphia International Airport, fly to Chicago Midway International Airport

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    7h 28m
    $122–532

  7. Bus via Baltimore (Greyhound)

    1. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0430
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    22h 38m
    $94–232

Enola to Chicago by bus and train (Amtrak)

Calendar7Weekly Services
Duration17h 28mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

What companies run services between Enola, PA, USA and Chicago, IL, USA?

You can take a bus from Enola Dr & Cumberland Rd to Chicago Union Station via Aberdeen St & StraWBerry St, Harrisburg, and Pittsburgh Amtrak Station in around 17h 28m. Alternatively, Flixbus USA operates a bus from Harrisburg Bus Station to Chicago Bus Station once daily. Tickets cost $80–190 and the journey takes 16h 30m.

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