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How to get fromDurham to Missouriby plane, bus (Flixbus, Greyhound), train (Amtrak), car or train

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There are 8 ways to get from Durham to Missouri by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Lambert–St. Louis International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)planeRDU - STL
    5h 1m
    $253–466

  2. Fly Raleigh-Durham International Airport to Springfield-Branson National Airport

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Springfield-Branson National Airport (SGF)planeRDU - SGF
    6h 40m
    $101–473

  3. Bus

    1. Take the bus from Durham to Atlanta Bus Stationbus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus
    24h 10m
    $151–395

  4. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Raleigh Union Stationtrain
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Kansas Citytrain
    34h 50m
    $244–1,141

  5. Drive 1,002.5 mi

    1. Drive from Durham to Kansas Citycar1,002.5 mi
    17h 51m
    $183–265

  6. Fly Raleigh-Durham International Airport to Kansas City

    1. Fly from Raleigh-Durham International Airport (RDU) to Kansas City (MCI)planeRDU - MCI
    6h 19m
    $240–493

  7. Train to Charlotte Douglas International Airport, fly to Lambert–St. Louis International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)planeCLT - STL
    7h 32m
    $251–411

  8. Train to Charlotte Douglas International Airport, fly to Springfield-Branson National Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
    2. Fly from Charlotte Douglas International Airport (CLT) to Springfield-Branson National Airport (SGF)planeCLT - SGF
    7h 27m
    $119–418

Durham to Missouri by bus

Calendar7Weekly Buses
Duration24h 10mAverage Duration
Ticket$151Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Missouri, USA?

Southwest Airlines, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from Durham to Kansas City Bus Station via Atlanta Bus Station and St Louis Bus Station in around 24h 10m.

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