Rome2Rio

How to get fromDurham to Missouriby plane, bus (Flixbus, Greyhound), train (Amtrak), car or train

Find Transport to Missouri

See all options

There are 9 ways to get from Durham to Missouri by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Lambert–St. Louis International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    5h 1m
    $253–466

  2. Fly Raleigh-Durham International Airport to Springfield-Branson National Airport

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Springfield-Branson National Airport (SGF)plane plane RDU - SGF
    6h 31m
    $101–473

  3. Bus

    1. Take the bus from Durham to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    24h 10m
    $151–395

  4. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    34h 50m
    $244–1,141

  5. Drive 1,002.5 mi

    1. Drive from Durham to Kansas Citycar car 1,002.5 mi
    17h 51m
    $183–265

  6. Fly Raleigh-Durham International Airport to Kansas City

    1. Fly from Raleigh-Durham International Airport (RDU) to Kansas City (MCI)plane plane RDU - MCI
    6h 19m
    $240–553

  7. Train to Charlotte Douglas International Airport, fly to Lambert–St. Louis International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    7h 32m
    $251–431

  8. Train to Charlotte Douglas International Airport, fly to Springfield-Branson National Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Springfield-Branson National Airport (SGF)plane plane CLT - SGF
    7h 27m
    $124–428

  9. Train to Charlotte Douglas International Airport, fly to Columbia Regional Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Columbia Regional Airport (COU)plane plane CLT - COU
    7h 21m
    $153–463

Durham to Missouri by bus

Calendar7Weekly Buses
Duration24h 10mAverage Duration
Ticket$151Cheapest Price
See schedules

Questions & Answers

What companies run services between Durham, NC, USA and Missouri, USA?

Southwest Airlines, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Durham to Kansas City Bus Station via Atlanta Bus Station and St Louis Bus Station in around 24h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Durham

Trips to Missouri

Popular routes