There are 8 ways to get from Durham to Milwaukee by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to General Mitchell International Airport
best- Fly from Raleigh-Durham International Airport (RDU) to General Mitchell International Airport (MKE)plane RDU - MKE
6h 33m$117–658Bus
- Take the bus from Durham to Washington Union Stationbus
- Take the bus from Washington Union Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
26h$162–266Train (Amtrak)
- Take the train from Durham Amtrak Station to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
28h 36m$298–715Drive 852.6 mi
- Drive from Durham to Milwaukeecar 852.6 mi
15h 12m$156–225Train to Charlotte Douglas International Airport, fly to General Mitchell International Airport
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to General Mitchell International Airport (MKE)plane CLT - MKE
7h 32m$147–692Fly Raleigh-Durham International Airport to Chicago O'Hare International Airport, bus
- Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane RDU - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
7h 9m$188–780Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport, bus
- Take the train from Durham Amtrak Station to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane GSO - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
6h 54m$123–476Fly Raleigh-Durham International Airport to Chicago Midway International Airport, train
- Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane RDU - MDW
- Take the train from Chicago Union Station to Milwaukeetrain
7h 37m$180–284
Durham to Milwaukee by bus
Comparing Your Travel Options
The cheapest way to get from Durham to Milwaukee is to drive which costs $150 - $230 and takes 15h 12m.
The fastest way to get from Durham to Milwaukee is to fly which takes 6h 33m and costs $110 - $700.
No, there is no direct bus from Durham to Milwaukee station. However, there are services departing from Durham and arriving at Milwaukee Intermodal Station via Washington Union Station and Chicago Bus Station. The journey, including transfers, takes approximately 26h.
No, there is no direct train from Durham station to Milwaukee. However, there are services departing from Durham Amtrak Station and arriving at Milwaukee via Raleigh Union Station and Chicago Union Station. The journey, including transfers, takes approximately 28h 36m.
The distance between Durham and Milwaukee is 716 miles. The road distance is 857.5 miles.
The best way to get from Durham to Milwaukee without a car is to bus which takes 26h and costs $160 - $270.
It takes approximately 6h 33m to get from Durham to Milwaukee, including transfers.
Durham to Milwaukee bus services, operated by Flixbus USA, depart from Durham station.
Durham to Milwaukee train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Durham to Milwaukee is to fly which takes 6h 33m and costs $110 - $700. Alternatively, you can bus, which costs $160 - $270 and takes 26h, you could also train, which costs $290 - $750 and takes 28h 36m.
What companies run services between Durham, NC, USA and Milwaukee, WI, USA?
Southwest Airlines, Delta, and two other airlines fly from Raleigh-Durham International Airport (RDU) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a bus from Durham to Milwaukee Intermodal Station via Washington Union Station and Chicago Bus Station in around 26h.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to General Mitchell International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 45m
- When
- Saturday and Sunday
- Estimated price
- $110–650
Flights from Charlotte Douglas International Airport to General Mitchell International Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- $100–600
Flights from Charlotte Douglas International Airport to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $110–600
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- $60–340
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $65–380
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $70–400
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Durham Amtrak Station to Raleigh Union Station
- Ave. Duration
- 39 min
- Frequency
- 5 times a day
- Estimated price
- $6–15
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $270–650
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $21–50
- Website
- Amtrak
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $35–85
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $14–35
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $21–50
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Durham to Washington Union Station
- Ave. Duration
- 5h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Durham to Milwaukee bus services, operated by Flixbus USA, arrive at Washington Union Station.
Milwaukee is 1h behind Durham. It is currently 2:28 PM in Durham and 1:28 PM in Milwaukee.
Durham to Milwaukee train services, operated by Amtrak, arrive at Raleigh Union Station.
Yes, the driving distance between Durham to Milwaukee is 858 miles. It takes approximately 15h 12m to drive from Durham to Milwaukee.
Book your Durham to Milwaukee train tickets online with Omio.
Book your Durham to Milwaukee bus tickets online with Omio and FlixBus.
There are 313+ hotels available in Milwaukee.






