There are 6 ways to get from Durham to Key West by bus, plane, bus (Flixbus, Greyhound), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 700 bus to Raleigh-Durham International Airport, fly
best- Take the bus from Pettigrew St at Parking Deck to Regional Transit Centerbus
- Fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW)plane RDU - EYW
4h 41m$161–276Bus
cheapest- Take the bus from Raleigh Bus Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
25h 11m$131–261Train, bus
- Take the train from Cary to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
30h 58m$292–666Drive 959.2 mi
- Drive from Durham to Key Westcar 959.2 mi
17h 15m$176–253Train to Piedmont Triad International Airport, fly
- Take the train from Durham Amtrak Station to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to Key West International Airport (EYW)plane GSO - EYW
6h 32m$176–735Train to Charlotte Douglas International Airport, fly
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane CLT - EYW
7h 8m$187–605
Durham to Key West by bus and foot
Questions & Answers
The cheapest way to get from Durham to Key West is to bus which costs $130 - $270 and takes 25h 11m.
The fastest way to get from Durham to Key West is to line 700 bus and fly which takes 4h 41m and costs $160 - $280.
No, there is no direct bus from Durham to Key West. However, there are services departing from Durham and arriving at N Roosevelt & 3rd Street via Raleigh Bus Station, Orlando Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 25h 11m.
The distance between Durham and Key West is 826 miles. The road distance is 964.8 miles.
The best way to get from Durham to Key West without a car is to bus which takes 25h 11m and costs $130 - $270.
It takes approximately 4h 41m to get from Durham to Key West, including transfers.
Durham to Key West bus services, operated by Flixbus USA, depart from Raleigh Bus Station.
Durham to Key West bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Durham to Key West is 965 miles. It takes approximately 17h 15m to drive from Durham to Key West.
There are 680+ hotels available in Key West.
What companies run services between Durham, NC, USA and Key West, FL, USA?
You can take a bus from Durham to N Roosevelt & 3rd Street via Raleigh Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 25h 11m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Raleigh-Durham International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $90–500
Flights from Piedmont Triad International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 9m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Piedmont Triad International Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $120–650
Flights from Piedmont Triad International Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 5h 20m
- When
- Sunday
- Estimated price
- $160–800
Flights from Piedmont Triad International Airport to Key West International Airport via Philadelphia
- Ave. Duration
- 6h 17m
- When
- Monday, Saturday, and Sunday
- Estimated price
- $180–900
Flights from Charlotte Douglas International Airport to Key West International Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- $85–470
Flights from Charlotte Douglas International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $85–480
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $100–550
Flights from Piedmont Triad International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $130–700
Flights from Charlotte Douglas International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $95–500
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Key West International Airport
- Ave. Duration
- 2h 20m
- When
- Monday and Friday
- Estimated price
- $150–260
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cary to Hollywood Amtrak Station
- Ave. Duration
- 21h 35m
- Frequency
- Once daily
- Estimated price
- $260–600
- Website
- https://www.amtrak.com/home.html
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $14–35
- Website
- https://www.amtrak.com/home.html
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from Pettigrew St at Parking Deck to Regional Transit Center
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Raleigh Bus Station to Orlando Bus Station
- Ave. Duration
- 11h 10m
- Frequency
- 5 times a week
- Estimated price
- $75–130
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $29–50
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–45
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
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