There are 5 ways to get from Durham to Key West by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Raleigh-Durham International Airport
best- Fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW)plane RDU - EYW
4h 28m$171–716Bus
cheapest- Take the bus from Raleigh Bus Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
25h 14m$132–318Train, bus
- Take the train from Cary to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
30h 58m$154–1,469Drive 959.2 mi
- Drive from Durham to Key Westcar 959.2 mi
17h 15m$176–253Train to Charlotte Douglas International Airport, fly
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane CLT - EYW
7h 12m$159–551
Durham to Key West by bus and foot
Questions & Answers
The cheapest way to get from Durham to Key West is to bus which costs $130 - $320 and takes 25h 14m.
The fastest way to get from Durham to Key West is to fly which takes 4h 28m and costs $170 - $750.
No, there is no direct bus from Durham to Key West. However, there are services departing from Durham and arriving at N Roosevelt & 3rd Street via Raleigh Bus Station, Orlando Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 25h 14m.
The distance between Durham and Key West is 825 miles. The road distance is 964.8 miles.
The best way to get from Durham to Key West without a car is to bus which takes 25h 14m and costs $130 - $320.
It takes approximately 4h 28m to get from Durham to Key West, including transfers.
Durham to Key West bus services, operated by Flixbus USA, depart from Raleigh Bus Station.
The best way to get from Durham to Key West is to fly which takes 4h 28m and costs $170 - $750. Alternatively, you can bus, which costs $130 - $320 and takes 25h 14m.
Durham to Key West bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Durham to Key West is 965 miles. It takes approximately 17h 15m to drive from Durham to Key West.
What companies run services between Durham, NC, USA and Key West, FL, USA?
Breeze Airways, Delta, and American Airlines fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from Durham to N Roosevelt & 3rd Street via Raleigh Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 25h 14m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $100–600
Flights from Raleigh-Durham International Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $110–600
Flights from Charlotte Douglas International Airport to Key West International Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $85–480
Flights from Charlotte Douglas International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $90–490
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $120–600
Flights from Charlotte Douglas International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $95–550
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Key West International Airport
- Ave. Duration
- 2h 20m
- When
- Monday and Friday
- Estimated price
- $160–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cary to Hollywood Amtrak Station
- Ave. Duration
- 21h 35m
- Frequency
- Once daily
- Estimated price
- $120–1,400
- Website
- https://www.amtrak.com/home.html
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $31–32
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Raleigh Bus Station to Orlando Bus Station
- Ave. Duration
- 11h 10m
- Frequency
- 5 times a week
- Estimated price
- $75–180
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Every 2 hours
- Estimated price
- $27–65
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–40
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
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