Rome2Rio

How to get fromDurham to Key Westby plane, bus (Flixbus, Greyhound), train, bus or car

Find Transport to Key West

See all options

There are 5 ways to get from Durham to Key West by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Raleigh-Durham International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW)planeRDU - EYW
    4h 38m
    $151–486
  2. Train, bus

    cheapest
    1. Take the train from Cary to Hollywood Amtrak Stationtrain
    2. Take the bus from Miami Airport Station to Big Pine Keybus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    30h 58m
    $118–347
  3. Bus

    1. Take the bus from Raleigh Bus Station to Orlando Bus Stationbus
    2. Take the bus from Orlando Bus Station to Miami Airport Stationbus
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    25h 12m
    $137–305
  4. Drive 959.2 mi

    1. Drive from Durham to Key Westcar959.2 mi
    17h 5m
    $176–253
  5. Train to Charlotte Douglas International Airport, fly

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
    2. Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)planeCLT - EYW
    7h 10m
    $159–501

Durham to Key West by bus and foot

Calendar5Weekly Services
Duration25h 12mAverage Duration
Ticket$137Cheapest Price
See schedules

Questions & Answers

What companies run services between Durham, NC, USA and Key West, FL, USA?

Breeze Airways, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW) every 2 hours. Alternatively, you can take a bus from Durham to N Roosevelt & 3rd Street via Raleigh Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 25h 12m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers