There are 5 ways to get from Durham to Key West by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Raleigh-Durham International Airport
best- Fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW)RDU - EYW
4h 38m$151–486Train, bus
cheapest- Take the train from Cary to Hollywood Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
30h 58m$118–347Bus
- Take the bus from Raleigh Bus Station to Orlando Bus Station
- Take the bus from Orlando Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
25h 12m$137–305Drive 959.2 mi
- Drive from Durham to Key West959.2 mi
17h 5m$176–253Train to Charlotte Douglas International Airport, fly
- Take the train from Durham Amtrak Station to Charlotte Amtrak Station
- Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)CLT - EYW
7h 10m$159–501
Durham to Key West by bus and foot
Questions & Answers
The cheapest way to get from Durham to Key West is to fly which costs $150 - $490 and takes 4h 38m.
The fastest way to get from Durham to Key West is to fly which takes 4h 38m and costs $150 - $490.
No, there is no direct bus from Durham to Key West. However, there are services departing from Durham and arriving at N Roosevelt & 3rd Street via Raleigh Bus Station, Orlando Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 25h 12m.
The distance between Durham and Key West is 825 miles. The road distance is 964.8 miles.
The best way to get from Durham to Key West without a car is to bus which takes 25h 12m and costs $130 - $310.
It takes approximately 4h 38m to get from Durham to Key West, including transfers.
Durham to Key West bus services, operated by Flixbus USA, depart from Raleigh Bus Station.
The best way to get from Durham to Key West is to fly which takes 4h 38m and costs $150 - $490. Alternatively, you can bus, which costs $130 - $310 and takes 25h 12m.
Durham to Key West bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Durham to Key West is 965 miles. It takes approximately 17h 5m to drive from Durham to Key West.
What companies run services between Durham, NC, USA and Key West, FL, USA?
Breeze Airways, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW) every 2 hours. Alternatively, you can take a bus from Durham to N Roosevelt & 3rd Street via Raleigh Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 25h 12m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $95–480
Flights from Raleigh-Durham International Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $95–490
Flights from Charlotte Douglas International Airport to Key West International Airport
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $75–400
Flights from Charlotte Douglas International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $75–400
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $100–550
Flights from Charlotte Douglas International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $85–420
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Key West International Airport
- Ave. Duration
- 2h 30m
- When
- Monday and Friday
- Estimated price
- $210–900
- Website
- spirit.com
Flights from Charlotte Douglas International Airport to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 4h 20m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $110–450
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cary to Hollywood Amtrak Station
- Ave. Duration
- 21h 35m
- Frequency
- Once daily
- Estimated price
- $85–280
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $85–240
- Coach Seat short notice purchase
- $120–280
- Business - advance purchase
- $160–700
- Business Class
- $250–650
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $31–33
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Raleigh Bus Station to Orlando Bus Station
- Ave. Duration
- 11h 10m
- Frequency
- 5 times a week
- Estimated price
- $80–170
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $27–60
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $29–55
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
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