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How to get fromDurham to Kentuckyby bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, or bus (Greyhound)

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There are 7 ways to get from Durham to Kentucky by bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Raleigh-Durham International Airport, fly to Covington

    best
    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Covington (CVG)plane plane RDU - CVG
    4h 55m
    $216–448

  2. Bus

    cheapest
    1. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    17h 30m
    $68–173

  3. Bus via Atlanta

    1. Take the bus from Durham to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    17h 8m
    $124–235

  4. Bus, train

    1. Take the bus from Durham to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    25h 8m
    $270–580

  5. Drive 497.5 mi

    1. Drive from Durham to Louisvillecar car 497.5 mi
    9h 28m
    $91–132

  6. Bus to Raleigh-Durham International Airport, fly to Louisville International Airport

    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    5h 7m
    $100–558

  7. Train to Charlotte Douglas International Airport, fly to Tri-State Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Tri-State Airport (HTS)plane plane CLT - HTS
    6h 28m
    $132–497

Durham to Kentucky by bus

Calendar14Weekly Buses
Duration17h 8mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Durham to Kentucky.ExpandLaunch map view
  • Distance: 420.3 mi
  • Duration: 4h 55m

What companies run services between Durham, NC, USA and Kentucky, USA?

You can take a bus from Durham to Louisville, KY via Atlanta Bus Station and Nashville in around 17h 8m.

Airlines
Train operators
Bus operators

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