Rome2Rio

How to get fromDurham to Kentuckyby bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, or bus (Greyhound, Flixbus, Amtrak)

Find Transport to Kentucky

See all options

There are 8 ways to get from Durham to Kentucky by bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, or bus (Greyhound, Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Raleigh-Durham International Airport, fly to Covington

    best
    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Covington (CVG)plane plane RDU - CVG
    5h 7m
    $102–610

  2. Drive  497.5 mi

    cheapest
    1. Drive from Durham to Louisvillecar car 497.5 mi
    9h 30m
    $91–132

  3. Bus via Atlanta

    1. Take the bus from Durham to Atlanta Downtownbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    16h 34m
    $127–206

  4. Train, bus (Amtrak)

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 44m
    $477–791

  5. Bus to Raleigh-Durham International Airport, fly to Louisville International Airport

    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    5h 17m
    $105–658

  6. Train to Charlotte Douglas International Airport, fly to Tri-State Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Tri-State Airport (HTS)plane plane CLT - HTS
    6h 16m
    $161–506

  7. Bus

    1. Take the bus from Durham to Greensboro Bus Stopbus bus
    2. Take the bus from Greensboro to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to Indianapolis Union Stationbus bus
    5. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    20h 55m
    $106–208

  8. Train, bus via Arlington (Amtrak)

    1. Take the train from Durham Amtrak Station to Alexandriatrain train
    2. Take the train from Alexandria to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    28h 24m
    $591–969

Durham to Kentucky by bus and subway

Calendar4Weekly Services
Duration16h 34mAverage Duration
Ticket$127Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Durham to Kentucky.ExpandLaunch map view
  • Distance: 420.6 mi
  • Duration: 5h 7m

What companies run services between Durham, NC, USA and Kentucky, USA?

You can take a bus from Durham to Louisville, KY via Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Nashville in around 16h 34m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There