Rome2Rio

How to get fromDurham to Isle of Palmsby train (Amtrak), bus (Flixbus, Greyhound), car, plane, train or bus

Find Transport to Isle of Palms

See all options

There are 6 ways to get from Durham to Isle of Palms by train (Amtrak), bus (Flixbus, Greyhound), car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Durham Amtrak Station to SelmatrainCarolinian
    2. Take the train from Selma to Charleston Amtrak StationtrainPalmetto
    6h 51m
    $61–115

  2. Drive 253.6 mi

    cheapest
    1. Drive from Durham to Isle of Palmscar253.6 mi
    5h 30m
    $47–67

  3. Bus

    1. Take the bus from Durham to Charlotte Bus Stationbus
    2. Take the bus from Charlotte Bus Station to Columbiabus
    3. Take the bus from Columbia to Charleston Amtrak Stationbus
    9h 19m
    $96–239

  4. Fly from Raleigh-Durham International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS)planeRDU - CHS
    5h 41m
    $145–430

  5. Train to Charlotte Douglas International Airport, fly

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
    2. Fly from Charlotte Douglas International Airport (CLT) to Charleston International Airport (CHS)planeCLT - CHS
    6h 22m
    $163–465

  6. Bus to Piedmont Triad International Airport, fly

    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus
    2. Fly from Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS)planeGSO - CHS
    8h 59m
    $321–813

Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS) flights

Calendar130Weekly Planes
Duration4hAverage Duration
Ticket$55Cheapest Price
See schedules

Questions & Answers

What companies run services between Durham, NC, USA and Isle of Palms, SC, USA?

You can take a train from Durham Amtrak Station to Isle of Palms via Selma and Charleston Amtrak Station in around 6h 51m. Alternatively, you can take a bus from Durham to Isle of Palms via Charlotte Bus Station, Columbia, and Charleston Amtrak Station in around 9h 19m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Durham

Trips to Isle of Palms

Popular routes