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How to get fromDurham to Iowaby plane, bus (Greyhound), train, bus, or car

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There are 9 ways to get from Durham to Iowa by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Des Moines

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Des Moines (DSM)plane plane RDU - DSM
    6h 46m
    $187–874

  2. Fly Raleigh-Durham International Airport to Quad City International Airport

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Quad City International Airport (MLI)plane plane RDU - MLI
    8h 24m
    $82–425

  3. Bus

    1. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    28h 10m
    $147–319

  4. Train, bus

    1. Take the train from Cary to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    35h 35m
    $363–812

  5. Drive 1,054 mi

    1. Drive from Durham to Des Moinescar car 1,054 mi
    18h 15m
    $193–278

  6. Fly Raleigh-Durham International Airport to Omaha

    1. Fly from Raleigh-Durham International Airport (RDU) to Omaha (OMA)plane plane RDU - OMA
    6h 41m
    $195–833

  7. Train to Charlotte Douglas International Airport, fly to Des Moines

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    7h 28m
    $246–1,017

  8. Train to Charlotte Douglas International Airport, fly to Quad City International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)plane plane CLT - MLI
    8h 47m
    $136–558

  9. Train, bus via Galesburg

    1. Take the train from Durham Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    35h 48m
    $401–887

Raleigh-Durham International Airport (RDU) to Des Moines (DSM) flights

Calendar115Weekly Planes
Duration5h 34mAverage Duration
Ticket$170Cheapest Price
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Questions & Answers

Map of how to get from Durham to Iowa.ExpandLaunch map view
  • Distance: 912.9 mi
  • Duration: 6h 46m

What companies run services between Durham, NC, USA and Iowa, USA?

Southwest Airlines, Delta, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Durham to Des Moines via Winston Salem(Trans Center), Columbus, Indianapolis Union Station, and Des Moines in around 28h 10m.

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