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How to get fromDurham to Iowaby plane, bus (Flixbus, Greyhound), train, bus or car

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There are 8 ways to get from Durham to Iowa by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Des Moines

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Des Moines (DSM)plane plane RDU - DSM
    6h 41m
    $187–974

  2. Fly Raleigh-Durham International Airport to Quad City International Airport

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Quad City International Airport (MLI)plane plane RDU - MLI
    8h 23m
    $72–395

  3. Bus

    1. Take the bus from Durham to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 10m
    $220–434

  4. Train, bus

    1. Take the train from Durham Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    35h 55m
    $365–786

  5. Drive 1,054 mi

    1. Drive from Durham to Des Moinescar car 1,054 mi
    18h 15m
    $193–278

  6. Fly Raleigh-Durham International Airport to Omaha

    1. Fly from Raleigh-Durham International Airport (RDU) to Omaha (OMA)plane plane RDU - OMA
    6h 46m
    $235–1,133

  7. Train to Charlotte Douglas International Airport, fly to Quad City International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)plane plane CLT - MLI
    8h 46m
    $108–454

  8. Train, bus via Warrensburg

    1. Take the train from Durham Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Warrensburg Amtrak Stationtrain train
    4. Take the bus from Warrensburg Chamber Of Commerce to Kansas City Bus Stationbus bus
    5. Take the bus from Kansas City to Des Moinesbus bus
    42h 50m
    $463–1,075

Raleigh-Durham International Airport (RDU) to Des Moines (DSM) flights

Calendar109Weekly Planes
Duration5h 26mAverage Duration
Ticket$179Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Iowa, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Durham to Des Moines via Washington Union Station, Chicago Bus Station, and Des Moines in around 33h 10m.

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