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How to get fromDurham to Iowaby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 9 ways to get from Durham to Iowa by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Des Moines

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Des Moines (DSM)plane plane RDU - DSM
    6h 46m
    $192–876

  2. Fly Raleigh-Durham International Airport to Quad City International Airport

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Quad City International Airport (MLI)plane plane RDU - MLI
    8h 18m
    $92–438

  3. Bus

    1. Take the bus from Durham to Atlanta Downtownbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    28h 39m
    $199–382

  4. Train, bus

    1. Take the train from Cary to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    35h 35m
    $402–812

  5. Drive 1,053.1 mi

    1. Drive from Durham to Des Moinescar car 1,053.1 mi
    18h 17m
    $193–278

  6. Fly Raleigh-Durham International Airport to Omaha

    1. Fly from Raleigh-Durham International Airport (RDU) to Omaha (OMA)plane plane RDU - OMA
    6h 41m
    $180–786

  7. Train to Charlotte Douglas International Airport, fly to Des Moines

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    7h 26m
    $250–1,071

  8. Train to Charlotte Douglas International Airport, fly to Quad City International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)plane plane CLT - MLI
    8h 42m
    $145–582

  9. Train, bus via Galesburg

    1. Take the train from Durham Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    35h 43m
    $436–898

Raleigh-Durham International Airport (RDU) to Des Moines (DSM) flights

Calendar146Weekly Planes
Duration5h 28mAverage Duration
Ticket$172Cheapest Price
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Questions & Answers

Map of how to get from Durham to Iowa.ExpandLaunch map view
  • Distance: 912.9 mi
  • Duration: 6h 46m

What companies run services between Durham, NC, USA and Iowa, USA?

Southwest Airlines, Delta, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Durham to Des Moines via Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, St Louis Bus Station, and Des Moines in around 28h 39m.

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