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How to get fromDurham to Indianaby bus, plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus)

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There are 10 ways to get from Durham to Indiana by bus, plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Raleigh-Durham International Airport, fly to Indianapolis

    best
    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane plane RDU - IND
    5h 17m
    $166–378

  2. Bus

    cheapest
    1. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to Indianapolis Union Stationbus bus
    17h 5m
    $71–161

  3. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    21h 49m
    $220–513

  4. Drive 587.9 mi

    1. Drive from Durham to Indianapoliscar car 587.9 mi
    10h 27m
    $108–155

  5. Fly Raleigh-Durham International Airport to Chicago Midway International Airport, train

    1. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 4m
    $163–240

  6. Fly Raleigh-Durham International Airport to Chicago O'Hare International Airport, train

    1. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane plane RDU - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 45m
    $183–770

  7. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport, train

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 35m
    $124–497

  8. Train to Charlotte Douglas International Airport, fly to Indianapolis

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane plane CLT - IND
    7h 32m
    $138–646

  9. Bus via Atlanta (Flixbus)

    1. Take the bus from Durham to Atlanta Downtownbus bus FlixBus N2470
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    19h 19m
    $131–218

  10. Train via Arlington (Amtrak)

    1. Take the train from Durham Amtrak Station to Alexandriatrain train Carolinian
    2. Take the train from Alexandria to Indianapolistrain train Cardinal
    25h 29m
    $278–623

Durham to Indiana by bus

Calendar7Weekly Buses
Duration17h 5mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

Map of how to get from Durham to Indiana.ExpandLaunch map view
  • Distance: 519.5 mi
  • Duration: 5h 17m

What companies run services between Durham, NC, USA and Indiana, USA?

You can take a bus from Durham to Indianapolis Union Station via Winston Salem(Trans Center) and Columbus in around 17h 5m. Alternatively, you can take a train from Durham Amtrak Station to Indianapolis via Greensboro and Charlottesville in around 21h 49m.

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