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How to get fromDurham to Hyannisby plane, bus (Flixbus), train, bus, car or bus (Greyhound)

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There are 7 ways to get from Durham to Hyannis by plane, bus (Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barnstable Municipal Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Barnstable Municipal Airport (HYA)plane plane RDU - HYA
    6h 14m
    $95–553

  2. Bus via Boston

    1. Take the bus from Durham to New York, NYbus bus
    2. Take the bus from New York City Chinatown to Bostonbus bus
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus
    15h 57m
    $118–193

  3. Train, bus via New York

    1. Take the train from Durham Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus
    18h 13m
    $201–1,126

  4. Drive 722.7 mi

    1. Drive from Durham to Hyanniscar car 722.7 mi
    13h 24m
    $132–191

  5. Fly to Boston Logan Airport, bus

    1. Fly from Raleigh-Durham International Airport (RDU) to Boston Logan Airport (BOS)plane plane RDU - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    7h 1m
    $188–543

  6. Train, bus

    1. Take the train from Durham Amtrak Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    18h 56m
    $162–642

  7. Bus

    1. Take the bus from Durham to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Peter Pan Bus Terminalbus bus
    3. Take the bus from Providence Bus Terminal to Hyannis Transportation Centerbus bus
    20h 45m
    $149–311

Durham to Hyannis by train and bus

Calendar7Weekly Services
Duration18h 13mAverage Duration
Ticket$201Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Hyannis, MA, USA?

American Airlines, JetBlue Airways, and Cape Air fly from Raleigh-Durham International Airport (RDU) to Barnstable Municipal Airport (HYA) 5 times a day. Alternatively, you can take a bus from Durham to Hyannis Transportation Center via New York, NY, New York City Chinatown, Boston, and Boston South Station in around 15h 57m.

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