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How to get fromDurham to Hyannisby plane, bus (Flixbus), train, bus, car or bus (Greyhound)

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There are 7 ways to get from Durham to Hyannis by plane, bus (Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barnstable Municipal Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Barnstable Municipal Airport (HYA)planeRDU - HYA
    5h 43m
    $290–403

  2. Bus

    cheapest
    1. Take the bus from Durham to Port Authority Bus Terminalbus
    2. Take the bus from Port Authority Bus Terminal to Peter Pan Bus Terminalbus
    3. Take the bus from Providence Bus Terminal to Hyannis Transportation Centerbus
    20h 45m
    $108–251

  3. Bus via Boston

    1. Take the bus from Durham to New York Midtownbus
    2. Take the bus from New York Midtown to Bostonbus
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus
    18h
    $114–262

  4. Train, bus via New York

    1. Take the train from Durham Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus
    18h 13m
    $135–1,067

  5. Drive 722.6 mi

    1. Drive from Durham to Hyanniscar722.6 mi
    13h 18m
    $132–191

  6. Fly to Boston Logan Airport, bus

    1. Fly from Raleigh-Durham International Airport (RDU) to Boston Logan Airport (BOS)planeRDU - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus
    6h 51m
    $148–443

  7. Train, bus

    1. Take the train from Durham Amtrak Station to Petersburg Amtrak Stationtrain
    2. Take the train from Petersburg Amtrak Station to Bostontrain
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus
    18h 56m
    $132–616

Durham to Hyannis by bus

Calendar12Weekly Buses
Duration18hAverage Duration
Ticket$114Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Hyannis, MA, USA?

American Airlines, JetBlue Airways, and Cape Air fly from Raleigh-Durham International Airport (RDU) to Barnstable Municipal Airport (HYA) 5 times a day. Alternatively, you can take a bus from Durham to Hyannis Transportation Center via New York Midtown, Boston, and Boston South Station in around 18h.

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