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How to get fromDurham to Florida Keysby plane, bus (Flixbus, Greyhound), train, bus, car or shuttle

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There are 7 ways to get from Durham to Florida Keys by plane, bus (Flixbus, Greyhound), train, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Key West International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW)planeRDU - EYW
    7h 25m
    $187–542

  2. Bus

    cheapest
    1. Take the bus from Raleigh Bus Station to Orlando Bus Stationbus
    2. Take the bus from Orlando Bus Station to Miami Airport Stationbus
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    24h 26m
    $137–354

  3. Train, bus

    1. Take the train from Cary to Miami Amtrak StationtrainFloridian
    2. Take the bus from Miami Airport Station to Big Pine KeybusGreyhound US0720s
    29h 35m
    $141–380

  4. Drive 943.8 mi

    1. Drive from Durham to Florida Keyscar943.8 mi
    16h 42m
    $173–249

  5. Fly Raleigh-Durham International Airport to Miami International Airport, shuttle

    1. Fly from Raleigh-Durham International Airport (RDU) to Miami International Airport (MIA)planeRDU - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
    9h 47m
    $272–607

  6. Fly Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Raleigh-Durham International Airport (RDU) to Fort Lauderdale–Hollywood International Airport (FLL)planeRDU - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle
    10h 9m
    $197–517

  7. Train to Charlotte Douglas International Airport, fly to Key West International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
    2. Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)planeCLT - EYW
    9h 58m
    $195–488

Durham to Florida Keys by bus and foot

Calendar5Weekly Services
Duration24h 26mAverage Duration
Ticket$137Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Florida Keys, FL, USA?

Breeze Airways, Delta, and American Airlines fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Durham to Florida Keys via Raleigh Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 24h 26m.

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