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How to get fromDurham to Florida Keysby plane, bus (Flixbus, Greyhound), train, bus, car or shuttle

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There are 7 ways to get from Durham to Florida Keys by plane, bus (Flixbus, Greyhound), train, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Key West International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW)plane plane RDU - EYW
    7h 15m
    $207–772

  2. Train, bus

    cheapest
    1. Take the train from Cary to Miami Amtrak Stationtrain train Floridian
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    29h 35m
    $130–400

  3. Bus

    1. Take the bus from Raleigh Bus Station to Daytona Beachbus bus
    2. Take the bus from Daytona Beach to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    25h 35m
    $155–363

  4. Drive 943.8 mi

    1. Drive from Durham to Florida Keyscar car 943.8 mi
    16h 53m
    $173–249

  5. Fly Raleigh-Durham International Airport to Miami International Airport, shuttle

    1. Fly from Raleigh-Durham International Airport (RDU) to Miami International Airport (MIA)plane plane RDU - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 49m
    $272–677

  6. Fly Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Raleigh-Durham International Airport (RDU) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane RDU - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 9m
    $197–567

  7. Train to Charlotte Douglas International Airport, fly to Key West International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane plane CLT - EYW
    9h 59m
    $195–567

Durham to Florida Keys by bus and foot

Calendar5Weekly Services
Duration25h 35mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Florida Keys, FL, USA?

Breeze Airways, Delta, and American Airlines fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from Durham to Florida Keys via Raleigh Bus Station, Daytona Beach, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 25h 35m.

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