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How to get fromDurham to Buffaloby plane, bus (Flixbus), train (Amtrak), car, bus, train, shuttle or bus (Greyhound)

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There are 9 ways to get from Durham to Buffalo by plane, bus (Flixbus), train (Amtrak), car, bus, train, shuttle, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)planeRDU - BUF
    6h 33m
    $194–1,183

  2. Fly Raleigh-Durham International Airport to Rochester, bus

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Rochester (ROC)planeRDU - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    6h 57m
    $84–428

  3. Bus (Flixbus)

    1. Take the bus from Durham to New York MidtownbusFlixBus N2471 / ...
    2. Take the bus from New York Midtown to BuffalobusFlixBus N2686 / ...
    19h 21m
    $124–265

  4. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Ny Moynihan Train Hall At Penn StationtrainCarolinian
    2. Take the train from Ny Moynihan Train Hall At Penn Station to BuffalotrainEmpire Service / ...
    20h 55m
    $173–495

  5. Drive 581.9 mi

    1. Drive from Durham to Buffalocar581.9 mi
    12h 21m
    $107–154

  6. Train to Charlotte Douglas International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
    2. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)planeCLT - BUF
    7h 39m
    $212–1,119

  7. Fly Raleigh-Durham International Airport to Toronto Pearson International Airport, shuttle

    1. Fly from Raleigh-Durham International Airport (RDU) to Toronto Pearson International Airport (YYZ)planeRDU - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle
    8h 43m
    $254–853

  8. Bus via New York

    1. Take the bus from Durham to Port Authority Bus TerminalbusGreyhound US0670
    2. Take the bus from Port Authority Bus Terminal to BuffalobusGreyhound US0215 / ...
    22h 35m
    $122–291

  9. Bus, train

    1. Take the bus from Durham Station Gate G to Union Station - Bus Platform AbusDrx
    2. Take the train from Raleigh Union Station to Pittsburgh Amtrak Stationtrain
    3. Take the bus from Pittsburgh to Buffalobus
    25h 20m
    $150–1,030

Durham to Buffalo by bus (Flixbus)

Calendar12Weekly Buses
Duration19h 21mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Durham to Buffalo via New York Midtown in around 19h 21m.

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