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How to get fromDurham to Buffaloby plane, bus (Flixbus), train (Amtrak), car, bus, train or bus (Greyhound)

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There are 9 ways to get from Durham to Buffalo by plane, bus (Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane plane RDU - BUF
    6h 43m
    $184–1,183

  2. Fly Raleigh-Durham International Airport to Rochester, bus

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Rochester (ROC)plane plane RDU - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus bus
    7h 3m
    $79–418

  3. Bus (Flixbus)

    1. Take the bus from Durham to New York Midtownbus bus FlixBus N2471 / ...
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    19h 30m
    $118–252

  4. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Carolinian
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    20h 55m
    $157–412

  5. Drive 581.8 mi

    1. Drive from Durham to Buffalocar car 581.8 mi
    12h 27m
    $107–154

  6. Train to Charlotte Douglas International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane plane CLT - BUF
    7h 49m
    $201–1,118

  7. Train to Piedmont Triad International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF)plane plane GSO - BUF
    9h 19m
    $251–1,499

  8. Bus via New York

    1. Take the bus from Durham to Port Authority Bus Terminalbus bus Greyhound US0670
    2. Take the bus from Port Authority Bus Terminal to Buffalobus bus Greyhound US0215 / ...
    22h 35m
    $114–274

  9. Bus, train

    1. Take the bus from Durham Station Gate G to Union Station - Bus Platform Abus bus Drx
    2. Take the train from Raleigh Union Station to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh to Buffalobus bus
    25h 20m
    $150–510

Durham to Buffalo by bus (Flixbus)

Calendar12Weekly Buses
Duration19h 30mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Buffalo, NY, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF) every 2 hours. Alternatively, you can take a bus from Durham to Buffalo via New York Midtown in around 19h 30m.

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