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How to get fromDurham to Baltimoreby bus (Flixbus, Greyhound), train (Amtrak), car, bus, plane, train, or subway

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There are 11 ways to get from Durham to Baltimore by bus (Flixbus, Greyhound), train (Amtrak), car, bus, plane, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Durham to Baltimore Downtown Bus Stationbus bus FlixBus N2471
    6h 25m
    $40–85

  2. Bus via O'Donnell St Cutoff & Travel Center #2

    cheapest
    1. Take the bus from Durham, NC - 3446 Hillsborough Rd to Baltimore, MD - 1200 Ponca Stbus bus Charlotte
    8h 17m
    $30–58

  3. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Baltimore Penn Stationtrain train Carolinian
    8h 20m
    $110–240

  4. Drive 294.3 mi

    1. Drive from Durham to Baltimorecar car 294.3 mi
    5h 13m
    $54–78

  5. Line 700 bus to Raleigh-Durham International Airport, fly to Baltimore-Washington International Airport

    1. Take the bus from Pettigrew St at Parking Deck to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Baltimore-Washington International Airport (BWI)plane plane RDU - BWI
    4h 8m
    $228–658

  6. Bus via O'Donnell St Cutoff & Travel Center

    1. Take the bus from Durham to Baltimore, MDbus bus Augusta
    6h 31m
    $55–74

  7. Fly Raleigh-Durham International Airport to Ronald Reagan Washington National Airport, train

    1. Fly from Raleigh-Durham International Airport (RDU) to Ronald Reagan Washington National Airport (DCA)plane plane RDU - DCA
    2. Take the train from Washington Union Station to Baltimore Penn Stationtrain train
    5h 2m
    $86–1,162

  8. Train to Piedmont Triad International Airport, fly to Ronald Reagan Washington National Airport, train

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Ronald Reagan Washington National Airport (DCA)plane plane GSO - DCA
    3. Take the train from Washington Union Station to Baltimore Penn Stationtrain train
    5h 11m
    $148–1,331

  9. Fly Raleigh-Durham International Airport to Washington Dulles International Airport, subway, train

    1. Fly from Raleigh-Durham International Airport (RDU) to Washington Dulles International Airport (IAD)plane plane RDU - IAD
    2. Take the subway from Washington Dulles International Airport, Silver Line Center Platform to New Carrollton, Orange Line Center Platformsubway subway
    3. Take the train from New Carrollton Amtrak Station to Baltimore Penn Stationtrain train
    6h 1m
    $370–1,426

  10. Train to Piedmont Triad International Airport, fly to Washington Dulles International Airport, subway, train

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Washington Dulles International Airport (IAD)plane plane GSO - IAD
    3. Take the subway from Washington Dulles International Airport, Silver Line Center Platform to New Carrollton, Orange Line Center Platformsubway subway
    4. Take the train from New Carrollton Amtrak Station to Baltimore Penn Stationtrain train
    6h 11m
    $101–444

  11. Fly Raleigh-Durham International Airport to Philadelphia International Airport, train

    1. Fly from Raleigh-Durham International Airport (RDU) to Philadelphia International Airport (PHL)plane plane RDU - PHL
    2. Take the train from 30th Street Station to Baltimore Penn Stationtrain train
    5h 55m
    $140–1,058

Durham to Baltimore by bus

Calendar19Weekly Buses
Duration6h 25mAverage Duration
Ticket$40Cheapest Price
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Questions & Answers

Map of how to get from Durham to Baltimore.ExpandLaunch map view
  • Distance: 296.8 mi
  • Duration: 6h 25m

What companies run services between Durham, NC, USA and Baltimore, MD, USA?

Flixbus USA operates a bus from Durham to Baltimore Downtown Bus Station twice daily. Tickets cost $40–70 and the journey takes 6h 25m. Greyhound USA also services this route once daily. Alternatively, Amtrak operates a train from Durham Amtrak Station to Baltimore Penn Station once daily. Tickets cost $110–240 and the journey takes 8h 20m.

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