Southwest Airlines, Delta and American Airlines fly from Durham to Nashville hourly. Alternatively, Greyhound USA operates a bus from Durham to Nashville once daily. Tickets cost $50 - $130 and the journey takes 11 h 8 min.
From GoDurham Station line 700 bus to Regional Transit Center, line 100 bus to Raleigh/Durham airport, fly to Nashville airport, then bus to Nashville. 4 h 6 min $204. From Durham bus to Nashville. 11 h 8 min $99. From Durham drive to Nashville. 8 h 54 min $62.