There are 8 ways to get from Duke University to Lexington by plane, car, bus (Flixbus, Greyhound), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to Louisville International Airport, drive
best- Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)RDU - SDF
- Drive from Louisville-Airport-SDF to Lexington
5h 49m$155–425Drive 423.6 mi
cheapest- Drive from Duke University to Lexington423.6 mi
8h 31m$78–112Bus via Atlanta
- Take the bus from Durham to Atlanta DowntownFlixBus N2470
- Take the bus from Atlanta Bus Station to Lexington Bus StopGreyhound US0110
17h 6m$131–281Bus, train
- Take the bus from Chapel Dr at Duke University Rd to Union Station - Bus Platform ADrx
- Take the train from Raleigh Union Station to Toledo
- Take the bus from Toledo Bus Stop to Lexington Bus Stop
30h 30m$147–372Fly Raleigh-Durham International Airport to Blue Grass Airport
- Fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX)RDU - LEX
9h 3m$133–806Train to Charlotte Douglas International Airport, fly to Louisville International Airport, drive
- Take the train from Durham Amtrak Station to Charlotte Amtrak Station
- Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)CLT - SDF
- Drive from Louisville-Airport-SDF to Lexington
8h 50m$182–481Train to Piedmont Triad International Airport, fly to Blue Grass Airport
- Take the train from Durham Amtrak Station to Greensboro
- Fly from Piedmont Triad International Airport (GSO) to Blue Grass Airport (LEX)GSO - LEX
10h 8m$178–932Bus
- Take the bus from Durham to Atlanta Bus StationFlixBus N2471 / ...
- Take the bus from Atlanta Bus Station to Lexington Bus StopGreyhound US0110
17h 42m$128–293
Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Duke University to Lexington is to drive which costs $75 - $120 and takes 8h 31m.
The fastest way to get from Duke University to Lexington is to fly and drive which takes 5h 49m and costs $150 - $430.
The distance between Duke University and Lexington is 516 miles. The road distance is 426.1 miles.
The best way to get from Duke University to Lexington without a car is to bus via Atlanta which takes 17h 6m and costs $130 - $290.
It takes approximately 5h 49m to get from Duke University to Lexington, including transfers.
The best way to get from Duke University to Lexington is to bus via Atlanta which takes 17h 6m and costs $130 - $290. Alternatively, you can fly, which costs $130 - $850 and takes 9h 3m.
Yes, the driving distance between Duke University to Lexington is 426 miles. It takes approximately 8h 31m to drive from Duke University to Lexington.
There are 134+ hotels available in Lexington.
What companies run services between Duke University, NC, USA and Lexington, KY, USA?
You can take a vehicle from Duke University to Lexington via Flowers Dr at Duke Gardens, Durham Station, Durham, Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Lexington Bus Stop in around 17h 6m. Alternatively, American Airlines, Delta, and United Airlines fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX) hourly.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 41m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $85–500
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $130–800
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 6h 13m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- $200–1,000
Flights from Charlotte Douglas International Airport to Louisville International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $65–410
Flights from Piedmont Triad International Airport to Blue Grass Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 2m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $150–900
Flights from Piedmont Triad International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Piedmont Triad International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 7h 18m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- $230–1,200
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 53m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $170–950
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Raleigh-Durham International Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 5h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,100
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Reagan Washington
- Ave. Duration
- 7h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–900
Flights from Charlotte Douglas International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–460
Flights from Piedmont Triad International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Piedmont Triad International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 7h 33m
- When
- Every day
- Estimated price
- $210–1,200
- Website
- united.com
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 36m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Piedmont Triad International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $240–1,200
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 3h 55m
- When
- Friday and Sunday
- Estimated price
- $110–600
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Louisville International Airport
- Ave. Duration
- 1h 32m
- When
- Thursday and Sunday
- Estimated price
- $200–310
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Raleigh Union Station to Toledo
- Ave. Duration
- 20h
- Frequency
- Once daily
- Estimated price
- $75–250
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $75–210
- Coach Seat short notice purchase
- $100–250
- Business - advance purchase
- $140–600
- Business Class
- $230–600
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $31–33
- Website
- https://www.amtrak.com/home.html
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $11–13
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Durham to Atlanta Downtown
- Ave. Duration
- 6h 45m
- Frequency
- 6 times a week
- Estimated price
- $50–95
- Schedules at
- flixbus.com
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 7h 30m
- Frequency
- 5 times a day
- Estimated price
- $50–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to Lexington Bus Stop
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $50–150
- Website
- https://www.greyhound.com/
Bus from Toledo Bus Stop to Lexington Bus Stop
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- 4 times a day
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from Chapel Dr at Duke University Rd to Union Station - Bus Platform A
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
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