There are 4 ways to get from Duke University to Lexington by car or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive 423.8 mi
best- Drive from Duke University to Lexingtoncar 423.8 mi
8h 24m$78–112Fly to Louisville International Airport, drive
- Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane RDU - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
5h 56m$205–675Fly to Covington, drive
- Fly from Raleigh-Durham International Airport (RDU) to Covington (CVG)plane RDU - CVG
- Drive from Covington (CVG) to Lexingtoncar
6h 4m$116–676Fly to Blue Grass Airport
- Fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX)plane RDU - LEX
8h 40m$113–706
Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Duke University to Lexington is to drive which costs $75 - $120 and takes 8h 24m.
The fastest way to get from Duke University to Lexington is to fly and drive which takes 5h 56m and costs $200 - $700.
The distance between Duke University and Lexington is 426 miles. The road distance is 426.2 miles.
It takes approximately 8h 24m to drive 426.2 miles from Duke University to Lexington.
Yes, the driving distance between Duke University to Lexington is 426 miles. It takes approximately 8h 24m to drive from Duke University to Lexington.
There are 157+ hotels available in Lexington.
What companies run services between Duke University, NC, USA and Lexington, KY, USA?
American Airlines, Delta, and United Airlines fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX) hourly.
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $100–600
Flights from Raleigh-Durham International Airport to Covington
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $100–650
Flights from Raleigh-Durham International Airport to Covington via Atlanta
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $140–800
Flights from Raleigh-Durham International Airport to Covington via Detroit
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $140–800
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $140–850
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $160–900
Flights from Raleigh-Durham International Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 6h 21m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–1,000
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Reagan Washington
- Ave. Duration
- 7h 37m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–850
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $80–500
Flights from Raleigh-Durham International Airport to Covington via Charlotte
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $110–700
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $110–700
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 4h 54m
- When
- Saturday
- Estimated price
- $170–950
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–1,000
- Website
- united.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $100–600
Flights from Raleigh-Durham International Airport to Covington via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $120–750
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $180–1,000
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $100–600
Flights from Raleigh-Durham International Airport to Covington via Baltimore
- Ave. Duration
- 3h 52m
- When
- Monday to Friday
- Estimated price
- $130–800
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Louisville International Airport
- Ave. Duration
- 1h 37m
- When
- Thursday and Sunday
- Estimated price
- $160–1,300
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