There are 6 ways to get from Duke University to Chicago by bus, plane, bus (Flixbus, Greyhound), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 6 bus, line 700 bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport
best- Take the bus from Flowers Dr at Duke Gardens to Durham Station
- Take the bus from Durham Station Gate J to Regional Transit Center
- Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)RDU - MDW
5h 30m$83–449Bus
- Take the bus from Durham to Washington Union StationFlixBus N2471 / ...
- Take the bus from Washington Union Station to Chicago Bus StationGreyhound US0164
24h 59m$111–331Bus, train
- Take the bus from Chapel Dr at Duke University Rd to Union Station - Bus Platform ADrx
- Take the train from Raleigh Union Station to Chicago Union StationFloridian
26h 50m$200–1,400Drive 764 mi
- Drive from Duke University to Chicago764 mi
13h 16m$140–202Line 6 bus, line 700 bus to Raleigh-Durham International Airport, fly to Chicago O'Hare International Airport
- Take the bus from Flowers Dr at Duke Gardens to Durham Station
- Take the bus from Durham Station Gate J to Regional Transit Center
- Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)RDU - ORD
6h 1m$88–369Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport
- Take the train from Durham Amtrak Station to Greensboro
- Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)GSO - ORD
7h 16m$93–415
Duke University to Chicago by foot and bus
Questions & Answers
The cheapest way to get from Duke University to Chicago is to drive which costs $130 - $210 and takes 13h 16m.
The fastest way to get from Duke University to Chicago is to line 6 bus and line 700 bus and fly which takes 5h 30m and costs $80 - $450.
No, there is no direct bus from Duke University to Chicago station. However, there are services departing from Flowers Dr at Duke Gardens and arriving at Chicago Bus Station via Durham and Washington Union Station. The journey, including transfers, takes approximately 24h 59m.
The distance between Duke University and Chicago is 664 miles. The road distance is 768.4 miles.
The best way to get from Duke University to Chicago without a car is to bus which takes 24h 59m and costs $110 - $340.
It takes approximately 5h 30m to get from Duke University to Chicago, including transfers.
Duke University to Chicago bus services, operated by Flixbus USA, depart from Durham station.
Duke University to Chicago bus services, operated by Flixbus USA, arrive at Washington Union Station.
Chicago is 1h behind Duke University. It is currently 5:43 AM in Duke University and 4:43 AM in Chicago.
Yes, the driving distance between Duke University to Chicago is 768 miles. It takes approximately 13h 16m to drive from Duke University to Chicago.
What companies run services between Duke University, NC, USA and Chicago, IL, USA?
You can take a vehicle from Duke University to Chicago Bus Station via Flowers Dr at Duke Gardens, Durham Station, Durham, and Washington Union Station in around 24h 59m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $60–330
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport via Pittsburgh
- Ave. Duration
- 4h 44m
- When
- Friday
- Estimated price
- $65–350
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $65–380
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $70–390
- Website
- united.com
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- $60–330
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $65–380
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $80–420
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $80–440
- Website
- delta.com
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 37m
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- $70–400
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 44m
- When
- Thursday
- Estimated price
- $85–440
- Website
- flyfrontier.com
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 28m
- When
- Sunday
- Estimated price
- $60–330
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 37m
- Frequency
- Once daily
- Estimated price
- $200–1,400
- Website
- https://www.amtrak.com/home.html
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $11–13
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Flowers Dr at Duke Gardens to Durham Station
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from Durham Station Gate J to Regional Transit Center
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
Bus from Chapel Dr at Duke University Rd to Union Station - Bus Platform A
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Durham to Washington Union Station
- Ave. Duration
- 5h 15m
- Frequency
- 3 times a day
- Estimated price
- $40–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Durham to Washington Union Station
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $40–140
- Website
- https://www.greyhound.com/
Bus from Washington Union Station to Chicago Bus Station
- Ave. Duration
- 17h 25m
- Frequency
- Twice daily
- Estimated price
- $70–190
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 1292+ hotels available in Chicago.








