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How to get fromDuke University to Chicagoby bus, plane, bus (Flixbus, Greyhound), train or car

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There are 6 ways to get from Duke University to Chicago by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 6 bus, line 700 bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Flowers Dr at Duke Gardens to Durham Stationbus bus
    2. Take the bus from Pettigrew St at Parking Deck to Regional Transit Centerbus bus
    3. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    5h 31m
    $83–469

  2. Bus

    1. Take the bus from Durham to Washington Union Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Washington Union Station to Chicago Bus Stationbus bus Greyhound US0164
    24h 59m
    $151–326

  3. Bus, train

    1. Take the bus from Chapel Dr at Duke University Rd to Union Station - Bus Platform Abus bus Drx
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    26h 55m
    $300–650

  4. Drive 764 mi

    1. Drive from Duke University to Chicagocar car 764 mi
    13h 27m
    $140–202

  5. Line 6 bus, line 700 bus to Raleigh-Durham International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Flowers Dr at Duke Gardens to Durham Stationbus bus
    2. Take the bus from Pettigrew St at Parking Deck to Regional Transit Centerbus bus
    3. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane plane RDU - ORD
    5h 56m
    $103–309

  6. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    6h 44m
    $103–421

Duke University to Chicago by foot and bus

Calendar14Weekly Services
Duration24h 59mAverage Duration
Ticket$151Cheapest Price
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Questions & Answers

What companies run services between Duke University, NC, USA and Chicago, IL, USA?

You can take a vehicle from Duke University to Chicago Bus Station via Flowers Dr at Duke Gardens, Durham Station, Durham, and Washington Union Station in around 24h 59m.

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