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How to get fromDubuque to St. Louisby car, plane, bus, train, or bus (Flixbus)

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There are 7 ways to get from Dubuque to St. Louis by car, plane, bus, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Quad City International Airport, fly

    best
    1. Drive from Dubuque to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL)plane plane MLI - STL
    5h 59m
    $87–474

  2. Drive  297.3 mi

    cheapest
    1. Drive from Dubuque to St. Louiscar car 297.3 mi
    6h 38m
    $55–79

  3. Bus, train

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to St. Louistrain train
    13h 12m
    $119–255

  4. Bus, train via Milwaukee

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    13h 20m
    $133–285

  5. Drive to The Eastern Iowa Airport, fly

    1. Drive from Dubuque to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Lambert–St. Louis International Airport (STL)plane plane CID - STL
    6h 24m
    $93–494

  6. Bus to General Mitchell International Airport, fly

    1. Take the bus from Dubuque to Milwaukeebus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    7h 53m
    $519–892

  7. Bus

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    14h 8m
    $93–160

Dubuque to St. Louis by bus and train

Calendar7Weekly Services
Duration13h 12mAverage Duration
Ticket$119Cheapest Price
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Questions & Answers

Map of how to get from Dubuque to St. Louis.ExpandLaunch map view
  • Distance: 280.1 mi
  • Duration: 5h 59m

What companies run services between Dubuque, IA, USA and St. Louis, MO, USA?

You can take a bus from Dubuque to St Louis Bus Station via Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Bus Station in around 14h 8m.

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