There are 4 ways to get from Drake University to St. Louis by plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
4h 20m$218–1,321Drive 332.2 mi
cheapest- Drive from Drake University to St. Louiscar 332.2 mi
6h 42m$61–88Bus
- Take the bus from Des Moines to Kansas Citybus Jefferson 803 / ...
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus Greyhound US0136 / ...
8h 39m$71–181Bus, train
- Take the bus from Des Moines to Kansas Citybus Jefferson 803 / ...
- Take the train from Kansas City to St. Louistrain Missouri River Runner / ...
11h 29m$91–256
Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Drake University to St. Louis is to drive which costs $60 - $90 and takes 6h 42m.
The fastest way to get from Drake University to St. Louis is to fly which takes 4h 20m and costs $210 - $1,400.
The distance between Drake University and St. Louis is 280 miles. The road distance is 334.2 miles.
The best way to get from Drake University to St. Louis without a car is to bus which takes 8h 39m and costs $70 - $190.
It takes approximately 4h 20m to get from Drake University to St. Louis, including transfers.
The best way to get from Drake University to St. Louis is to fly which takes 4h 20m and costs $210 - $1,400. Alternatively, you can bus, which costs $70 - $190 and takes 8h 39m.
Yes, the driving distance between Drake University to St. Louis is 334 miles. It takes approximately 6h 42m to drive from Drake University to St. Louis.
There are 545+ hotels available in St. Louis.
What companies run services between Drake University, IA, USA and St. Louis, MO, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Drake University to St Louis Bus Station via Des Moines and Kansas City Bus Station in around 8h 39m.
- Website
- delta.com
Flights from Des Moines to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Des Moines to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $340–1,700
Flights from Des Moines to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 6h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $290–1,500
- Website
- united.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $200–1,300
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $370–1,800
- Website
- aa.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $200–1,300
Flights from Des Moines to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $330–1,700
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 47m
- When
- Sunday
- Estimated price
- $200–1,300
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $370–1,800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $60–150
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide









