There are 6 ways to get from Dothan to Des Moines by plane, bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Dothan Regional Airport
best- Fly from Dothan Regional Airport (DHN) to Des Moines (DSM)plane DHN - DSM
5h 4m$186–881Drive 990.2 mi
cheapest- Drive from Dothan to Des Moinescar 990.2 mi
18h 11m$181–261Bus
- Take the bus from Dothan to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis to Burlingtonbus
- Take the bus from Burlington to Des Moinesbus
24h 55m$182–464Drive to Northwest Florida Beaches International Airport, fly
- Drive from Dothan to Northwest Florida Beaches International Airport (ECP)car
- Fly from Northwest Florida Beaches International Airport (ECP) to Des Moines (DSM)plane ECP - DSM
6h 27m$202–892Bus to Tallahassee, fly
- Take the bus from Dothan to Tallahasseebus
- Fly from Tallahassee (TLH) to Des Moines (DSM)plane TLH - DSM
8h 23m$280–1,209Bus, train
- Take the bus from Dothan to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus
- Take the train from Carbondale to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Burlingtonbus
- Take the bus from Burlington to Des Moinesbus
29h 21m$222–539
Dothan to Des Moines by bus
Questions & Answers
The cheapest way to get from Dothan to Des Moines is to drive which costs $180 - $270 and takes 18h 11m.
The fastest way to get from Dothan to Des Moines is to fly which takes 5h 4m and costs $180 - $900.
No, there is no direct bus from Dothan to Des Moines. However, there are services departing from Dothan and arriving at Des Moines via Nashville Bus Station, St Louis and Burlington. The journey, including transfers, takes approximately 24h 55m.
The distance between Dothan and Des Moines is 859 miles. The road distance is 996 miles.
The best way to get from Dothan to Des Moines without a car is to bus which takes 24h 55m and costs $180 - $470.
It takes approximately 5h 4m to get from Dothan to Des Moines, including transfers.
Dothan to Des Moines bus services, operated by Greyhound USA, depart from Dothan station.
The best way to get from Dothan to Des Moines is to fly which takes 5h 4m and costs $180 - $900. Alternatively, you can bus, which costs $180 - $470 and takes 24h 55m.
Dothan to Des Moines bus services, operated by Greyhound USA, arrive at Nashville Bus Station.
Yes, the driving distance between Dothan to Des Moines is 996 miles. It takes approximately 18h 11m to drive from Dothan to Des Moines.
What companies run services between Dothan, AL, USA and Des Moines, IA, USA?
Delta flies from Dothan Regional Airport (DHN) to Des Moines (DSM) twice daily. Alternatively, you can take a bus from Dothan to Des Moines via Nashville Bus Station, St Louis, and Burlington in around 24h 55m.
- Website
- delta.com
Flights from Dothan Regional Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $160–850
Flights from Northwest Florida Beaches International Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $170–850
Flights from Tallahassee to Des Moines via Atlanta
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $210–1,100
- Website
- aa.com
Flights from Northwest Florida Beaches International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 45m
- When
- Monday to Friday
- Estimated price
- $180–900
Flights from Northwest Florida Beaches International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 8h 4m
- When
- Every day
- Estimated price
- $200–950
Flights from Tallahassee to Des Moines via Charlotte
- Ave. Duration
- 5h 14m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,200
Flights from Tallahassee to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 7h 16m
- When
- Every day
- Estimated price
- $280–1,300
Flights from Tallahassee to Des Moines via Reagan Washington
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $310–1,400
Flights from Tallahassee to Des Moines via Miami
- Ave. Duration
- 8h 9m
- When
- Sunday
- Estimated price
- $330–1,500
- Website
- united.com
Flights from Northwest Florida Beaches International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 40m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $180–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $40–120
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $30–85
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Dothan to Nashville Bus Station
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $40–120
- Website
- https://www.greyhound.com/
Bus from Dothan to Tallahassee
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Nashville Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- $50–150
- Schedules at
- flixbus.com
Bus from Nashville Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $35–100
- Schedules at
- flixbus.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from St Louis to Burlington
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $50–127
- Website
- https://burlingtontrailways.com
- Saver Fares
- $50–75
- Flexible Fares
- $70–100
- Saver Fare
- $92
- Flex Fare
- $127
Bus from Burlington to Des Moines
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
Bus from Galesburg to Burlington
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 213+ hotels available in Des Moines.










