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How to get fromDomodossola to Mainzby train (Trenitalia), car, train or plane

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There are 9 ways to get from Domodossola to Mainz by train (Trenitalia), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Karlsruhe

    best
    1. Take the train from Domodossola to Basel SBBtrainEc
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain12 / ...
    3. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain12 / ...
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheatertrainS6
    7h 22m
    €107–212

  2. Train to Milan Linate Airport, fly

    cheapest
    1. Take the train from Domodossola to Rho Fiera Milanotrain
    2. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)planeLIN - FRA
    5h 55m
    €52–166

  3. Drive 627.9 km

    1. Drive from Domodossola to Mainzcar627.9 km
    6h 16m
    €98–142

  4. Train to Milano Malpensa Airport, fly

    1. Take the train from Domodossola to Gallaratetrain
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)planeMXP - FRA
    5h 14m
    €83–195

  5. Train

    1. Take the train from Domodossola to Basel SBBtrainEc
    2. Take the train from Basel SBB to FrankfurttrainEc
    7h 35m
    €171–305

  6. Train, train to Zurich Airport, fly

    1. Take the train from Brig to Berntrain
    2. Take the train from Bern to Zürich Flughafentrain
    3. Fly from Zurich Airport (ZRH) to Frankfurt (FRA)planeZRH - FRA
    6h 9m
    €169–375

  7. Train to Basel, fly

    1. Take the train from Domodossola to Basel SBBtrain
    2. Fly from Basel (BSL) to Frankfurt (FRA)planeBSL - FRA
    6h 40m
    €186–398

  8. Train to Geneva International Airport, fly

    1. Take the train from Brig to Genève-Aéroporttrain
    2. Fly from Geneva International Airport (GVA) to Frankfurt (FRA)planeGVA - FRA
    7h 29m
    €159–380

  9. Train, train to Turin Caselle Airport, fly

    1. Take the train from Domodossola to Rho Fiera Milanotrain
    2. Take the train from Rho-Fiera Milano to Torino Porta Susatrain
    3. Fly from Turin Caselle Airport (TRN) to Frankfurt (FRA)planeTRN - FRA
    7h 9m
    €125–357

Domodossola to Mainz by train

Calendar52Weekly Trains
Duration7h 22mAverage Duration
Ticket€107Cheapest Price
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Questions & Answers

What companies run services between Domodossola, Italy and Mainz, Germany?

You can take a train from Domodossola to Mainz, Römisches Theater via Basel SBB, Karlsruhe Hauptbahnhof, and Mannheim, Hauptbahnhof in around 7h 22m.

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