There are 7 ways to get from Detroit to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Detroit to Greenville/Spartanburg  •  3 h 43 min

  1. Fly from Detroit (DTW) to Greenville/Spartanburg (GSP) DTW - GSP

$192 - $847

Cheapest option

Bus  •  22 h 35 min

  1. Take the bus from Detroit, Mi to Columbia, Sc 1097 / ...
  2. Take the bus from Columbia, SC to Florence, SC Atlanta

$95 - $215

5 alternative options

Fly Detroit to Charlotte  •  4 h 10 min

  1. Fly from Detroit (DTW) to Charlotte (CLT) DTW - CLT

$267 - $452

Fly Detroit to Charleston  •  4 h 58 min

  1. Fly from Detroit (DTW) to Charleston (CHS) DTW - CHS

$154 - $325

Bus to Toledo, fly to Charlotte  •  4 h 48 min

  1. Take the bus from Detroit, Mi to Toledo, Oh
  2. Fly from Toledo (TOL) to Charlotte (CLT) TOL - CLT

$253 - $813

Bus, train  •  24 h 6 min

  1. Take the bus from Detroit, Mi to Toledo, Oh
  2. Take the train from Toledo Amtrak to Washington Union Station
  3. Take the train from Washington Union Station to Florence Amtrak

$158 - $438

Drive  •  13 h 17 min

  1. Drive from Detroit to Florence 739.6 miles

$70 - $110

Questions & Answers

No, there is no direct bus from Detroit to South Carolina. However, there are services departing from Detroit, Mi and arriving at Florence, SC via Columbia, SC. The journey, including transfers, takes approximately 22 h 35 min.

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The distance between Detroit and South Carolina is 617 miles. The road distance is 739.6 miles.

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The best way to get from Detroit to South Carolina without a car is to bus which takes 22 h 35 min and costs .

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It takes approximately 3 h 43 min to get from Detroit to South Carolina, including transfers.

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Detroit to South Carolina bus services, operated by Greyhound USA, depart from Detroit, Mi station.

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The best way to get from Detroit to South Carolina is to fly which takes 3 h 43 min and costs . Alternatively, you can bus, which costs and takes 22 h 35 min.

Mode details

The quickest flight from Detroit Airport to Greenville/Spartanburg Airport is the direct flight which takes 1 h 37 min.

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Detroit to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

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Yes, the driving distance between Detroit to South Carolina is 740 miles. It takes approximately 13 h 17 min to drive from Detroit to South Carolina.

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United Airlines, Southwest Airlines, American Airlines and Delta offer flights from Detroit Airport to Greenville/Spartanburg Airport.

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Map of how to get from Detroit to South Carolina.
Launch map view
  • Distance: 617.4 miles
  • Duration: 3 h 43 min

What companies run services between Detroit, MI, USA and South Carolina, USA?

Delta, American Airlines and two other airlines fly from Detroit to Greenville hourly. Alternatively, you can take a bus from Detroit to Florence via Columbia, Sc and Columbia, SC in around 22 h 35 min.

Airlines
Delta
Website
delta.com
Flights from Detroit to Greenville/Spartanburg
Ave. Duration
1 h 46 min
When
Every day
Estimated price
$280 - $1,600
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$280 - $1,600
Flights from Detroit to Charlotte
Ave. Duration
1 h 51 min
When
Every day
Estimated price
$280 - $750
Flights from Detroit to Charleston
Ave. Duration
2 h 8 min
When
Every day
Estimated price
$320 - $750
Flights from Detroit to Charleston via Atlanta
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$320 - $750
American Airlines
Website
aa.com
Flights from Detroit to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$300 - $650
Flights from Detroit to Charlotte
Ave. Duration
1 h 57 min
When
Every day
Estimated price
$280 - $750
Flights from Detroit to Charleston via Reagan Washington
Ave. Duration
4 h 13 min
When
Saturday and Sunday
Estimated price
$350 - $700
Flights from Detroit to Charleston via Charlotte
Ave. Duration
4 h 5 min
When
Monday, Tuesday, Friday and Saturday
Estimated price
$350 - $700
Flights from Toledo to Charlotte
Ave. Duration
1 h 44 min
When
Every day
Estimated price
$130 - $650
Southwest Airlines
Website
southwest.com
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h
When
Monday to Friday
Estimated price
$320 - $2,000
Flights from Detroit to Charleston via Chicago Midway
Ave. Duration
4 h
When
Monday to Friday
Estimated price
$410 - $750
Flights from Detroit to Charleston via Baltimore
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$410 - $750
Flights from Detroit to Charleston via Nashville
Ave. Duration
4 h 5 min
When
Saturday
Estimated price
$410 - $750
United Airlines
Website
united.com
Flights from Detroit to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$330 - $1,700
Flights from Detroit to Charlotte via Washington Dulles
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$310 - $750
Flights from Detroit to Charleston via Washington Dulles
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$400 - $750
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Toledo Amtrak to Washington Union Station
Ave. Duration
13 h 16 min
Frequency
Once daily
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $120
Flexi Coach Seat
$140 - $210
Business Coach Seat
$160 - $230
Room
$340 - $470
Train from Washington Union Station to Florence Amtrak
Ave. Duration
7 h 40 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Detroit, Mi to Toledo, Oh
Ave. Duration
1 h 10 min
Frequency
Every 15 minutes
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28
Bus from Detroit, Mi to Columbia, Sc
Ave. Duration
20 h 15 min
Frequency
Every 30 minutes
Estimated price
$75 - $190
Website
greyhound.com
Economy
$75 - $130
Flexible
$140 - $190

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More Questions & Answers

There are 17+ hotels available in South Carolina. Prices start at $51 USD per night.

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The best way to get from Detroit to Detroit Airport is to line 261 bus which takes 49 min and costs .

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