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There are 7 ways to get from Detroit to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Greenville/Spartanburg  •  4h 6m

  1. Fly from Detroit (DTW) to Greenville/Spartanburg (GSP) DTW - GSP

$192 - $847

Cheapest option

Bus  •  22h 35m

  1. Take the bus from Detroit, Mi to Columbia, Sc 1097 / ...
  2. Take the bus from Columbia, SC to Florence, SC Atlanta

$95 - $215

5 alternative options

Fly to Charleston  •  5h 3m

  1. Fly from Detroit (DTW) to Charleston (CHS) DTW - CHS

$154 - $325

Fly to Charlotte, bus  •  6h 41m

  1. Fly from Detroit (DTW) to Charlotte (CLT) DTW - CLT
  2. Take the bus from Transit Center- Bay X to White Street Park and Ride

$198 - $370

Fly to Myrtle Beach, bus  •  6h 33m

  1. Fly from Detroit (DTW) to Myrtle Beach (MYR) DTW - MYR
  2. Take the bus from Myrtle Beach to Florence, SC

$143 - $486

Bus, train  •  24h 6m

  1. Take the bus from Detroit, Mi to Toledo, Oh
  2. Take the train from Toledo Amtrak Station to Washington Union Station
  3. Take the train from Washington Union Station to Florence Amtrak Station

$158 - $438

Drive  •  13h 17m

  1. Drive from Detroit to Florence 739.6 miles

$70 - $110

Questions & Answers

The cheapest way to get from Detroit to South Carolina is to drive which costs $70 - $110 and takes 13h 17m.

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The quickest way to get from Detroit to South Carolina is to fly which costs $190 - $850 and takes 4h 6m.

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No, there is no direct bus from Detroit to South Carolina. However, there are services departing from Detroit, Mi and arriving at Florence, SC via Columbia, SC. The journey, including transfers, takes approximately 22h 35m.

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The distance between Detroit and South Carolina is 617 miles. The road distance is 739.6 miles.

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The best way to get from Detroit to South Carolina without a car is to bus which takes 22h 35m and costs $90 - $220.

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It takes approximately 4h 6m to get from Detroit to South Carolina, including transfers.

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Detroit to South Carolina bus services, operated by Greyhound USA, depart from Detroit, Mi station.

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The best way to get from Detroit to South Carolina is to fly which takes 4h 6m and costs $190 - $850. Alternatively, you can bus, which costs $90 - $220 and takes 22h 35m.

Mode details

The quickest flight from Detroit Airport to Greenville/Spartanburg Airport is the direct flight which takes 1h 55m.

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Detroit to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

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Map of how to get from Detroit to South Carolina.
Launch map view
  • Distance: 617.4 miles
  • Duration: 4h 6m

What companies run services between Detroit, MI, USA and South Carolina, USA?

Delta, American Airlines and two other airlines fly from Detroit to Greenville hourly. Alternatively, you can take a bus from Detroit to Florence via Columbia, Sc and Columbia, SC in around 22h 35m.

Airlines
Delta
Website
delta.com
Flights from Detroit to Greenville/Spartanburg
Ave. Duration
2h 1m
When
Every day
Estimated price
$280 - $1,600
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
4h 8m
When
Every day
Estimated price
$280 - $1,600
Flights from Detroit to Charleston
Ave. Duration
2h 6m
When
Every day
Estimated price
$320 - $750
Flights from Detroit to Charleston via Atlanta
Ave. Duration
4h 24m
When
Every day
Estimated price
$320 - $750
Flights from Detroit to Charlotte
Ave. Duration
2h 6m
When
Every day
Estimated price
$280 - $750
Flights from Detroit to Myrtle Beach
Ave. Duration
1h 59m
When
Saturday
Estimated price
$360 - $1,500
Flights from Detroit to Myrtle Beach via Atlanta
Ave. Duration
4h 26m
When
Every day
Estimated price
$360 - $1,500
American Airlines
Website
aa.com
Flights from Detroit to Greenville/Spartanburg via Charlotte
Ave. Duration
3h 52m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $650
Flights from Detroit to Greenville/Spartanburg via Reagan Washington
Ave. Duration
4h 11m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $650
Flights from Detroit to Charleston via Charlotte
Ave. Duration
4h 18m
When
Every day
Estimated price
$350 - $700
Flights from Detroit to Charleston via Reagan Washington
Ave. Duration
4h 24m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $700
Flights from Detroit to Charlotte
Ave. Duration
1h 58m
When
Every day
Estimated price
$280 - $750
Flights from Detroit to Myrtle Beach via Charlotte
Ave. Duration
4h 13m
When
Every day
Estimated price
$340 - $1,300
Southwest Airlines
Website
southwest.com
Flights from Detroit to Charleston via Baltimore
Ave. Duration
4h 5m
When
Sunday
Estimated price
$410 - $750
Flights from Detroit to Charleston via Chicago Midway
Ave. Duration
4h
When
Saturday
Estimated price
$410 - $750
Flights from Detroit to Charlotte via Nashville
Ave. Duration
3h 40m
When
Sunday
Estimated price
$310 - $950
Flights from Detroit to Charlotte via Baltimore
Ave. Duration
3h 52m
When
Monday to Saturday
Estimated price
$310 - $950
United Airlines
Website
united.com
Flights from Detroit to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3h 54m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $1,700
Flights from Detroit to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4h 12m
When
Monday and Tuesday
Estimated price
$330 - $1,700
Flights from Detroit to Charleston via Washington Dulles
Ave. Duration
4h 10m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$400 - $750
Spirit Airlines
Website
spirit.com
Flights from Detroit to Myrtle Beach
Ave. Duration
1h 55m
When
Every day
Estimated price
$160 - $850
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Toledo Amtrak Station to Washington Union Station
Ave. Duration
13h 16m
Frequency
Once daily
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $120
Flexi Coach Seat
$140 - $210
Business Coach Seat
$160 - $230
Room
$340 - $470
Train from Washington Union Station to Florence Amtrak Station
Ave. Duration
7h 40m
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from Transit Center- Bay X to White Street Park and Ride
Ave. Duration
1h 12m
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Myrtle Beach to Florence, SC
Ave. Duration
1h 30m
Frequency
Once daily
Estimated price
$18 - $29
Schedules at
southeasternstages.com
Bus from Columbia, SC to Florence, SC
Ave. Duration
1h 20m
Frequency
3 times a day
Estimated price
$19 - $29
Schedules at
southeasternstages.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Detroit, Mi to Columbia, Sc
Ave. Duration
20h 15m
Frequency
Every 4 hours
Estimated price
$75 - $190
Website
greyhound.com
Economy
$75 - $130
Flexible
$140 - $190
Bus from Detroit, Mi to Toledo, Oh
Ave. Duration
1h 10m
Frequency
Hourly
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28

Want to know more about travelling around United States

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More Questions & Answers

Yes, the driving distance between Detroit to South Carolina is 740 miles. It takes approximately 13h 17m to drive from Detroit to South Carolina.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Detroit Airport to Greenville/Spartanburg Airport.

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There are 18+ hotels available in South Carolina. Prices start at $49 USD per night.

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The best way to get from Detroit to Detroit Airport is to line 261 bus which takes 54m and costs $2.

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