There are 4 ways to get from Detroit to San Diego by plane, train (Amtrak), bus (Greyhound, Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Detroit (DTW) to San Diego International Airport (SAN)DTW - SAN
7h 19m$164–287Train (Amtrak)
- Take the train from Detroit to Chicago Union Station
- Take the train from Chicago Union Station to Fullerton Amtrak Station
- Take the train from Fullerton Amtrak Station to San Diego
2d 4h$227–509Bus
- Take the bus from Detroit, MI to Indianapolis, IN
- Take the bus from Indianapolis Union Station to St Louis Bus Station
- Take the bus from St Louis Bus Station to Los Angeles Union Station
- Take the bus from Los Angeles to San Diego
2d 7hDrive 2,340.9 mi
- Drive from Detroit to San Diego2,340.9 mi
36h 40m$428–618
Detroit to San Diego by train (Amtrak)
Questions & Answers
The cheapest way to get from Detroit to San Diego is to fly which costs $160 - $290 and takes 7h 19m.
The fastest way to get from Detroit to San Diego is to fly which takes 7h 19m and costs $160 - $290.
No, there is no direct bus from Detroit to San Diego. However, there are services departing from Detroit, MI and arriving at San Diego via Indianapolis Union Station, St Louis Bus Station and Los Angeles. The journey, including transfers, takes approximately 2 days 7h.
No, there is no direct train from Detroit to San Diego. However, there are services departing from Detroit and arriving at San Diego via Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 4h.
The distance between Detroit and San Diego is 1991 miles. The road distance is 2354.6 miles.
The best way to get from Detroit to San Diego without a car is to train which takes 2 days 4h and costs $220 - $550.
It takes approximately 7h 19m to get from Detroit to San Diego, including transfers.
Detroit to San Diego bus services, operated by Barons Bus, depart from Detroit, MI station.
Detroit to San Diego train services, operated by Amtrak, depart from Detroit station.
The best way to get from Detroit to San Diego is to fly which takes 7h 19m and costs $160 - $290. Alternatively, you can train, which costs $220 - $550 and takes 2 days 4h, you could also bus, which costs and takes 2 days 7h.
What companies run services between Detroit, MI, USA and San Diego, CA, USA?
Delta, Southwest Airlines, and two other airlines fly from Detroit (DTW) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a train from Detroit to San Diego via Chicago Union Station and Fullerton Amtrak Station in around 2d 4h.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- southwest.com
Flights from Detroit to San Diego International Airport via Denver
- Ave. Duration
- 6h 51m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $160–700
Flights from Detroit to San Diego International Airport via Chicago Midway
- Ave. Duration
- 6h 35m
- When
- Monday
- Estimated price
- $160–700
Flights from Detroit to San Diego International Airport via St. Louis
- Ave. Duration
- 6h 35m
- When
- Thursday
- Estimated price
- $160–700
Flights from Detroit to San Diego International Airport via Las Vegas
- Ave. Duration
- 7h 3m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $160–700
- Website
- delta.com
Flights from Detroit to San Diego International Airport
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $160–700
- Website
- united.com
Flights from Detroit to San Diego International Airport via Denver
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- $160–700
- Website
- aa.com
Flights from Detroit to San Diego International Airport via Phoenix
- Ave. Duration
- 7h 2m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $160–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Detroit to Chicago Union Station
- Ave. Duration
- 5h 6m
- Frequency
- 3 times a day
- Estimated price
- $45–130
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Twice daily
- Estimated price
- $150–350
- Website
- https://www.amtrak.com/home.html
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 23m
- Frequency
- Every 2 hours
- Estimated price
- $32–33
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Detroit, MI to Indianapolis, IN
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $27–70
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 39h 40m
- Frequency
- Twice daily
- Estimated price
- $120–360
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Los Angeles to San Diego
- Ave. Duration
- 3h
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Detroit to San Diego bus services, operated by Barons Bus, arrive at Indianapolis, IN station.
San Diego is 3h behind Detroit. It is currently 1:22 PM in Detroit and 10:22 AM in San Diego.
Detroit to San Diego train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Detroit to San Diego is 2355 miles. It takes approximately 36h 40m to drive from Detroit to San Diego.
Book your Detroit to San Diego train tickets online with Omio.
There are 1964+ hotels available in San Diego.









