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How to get fromDetroit to Port Isabelby plane, bus (Greyhound, Flixbus), train, bus, car or bus (Greyhound)

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There are 8 ways to get from Detroit to Port Isabel by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Brownsville-South Padre Island International Airport

    best
    1. Fly from Detroit (DTW) to Brownsville-South Padre Island International Airport (BRO)planeDTW - BRO
    9h 15m
    $124–604
  2. Bus via Dallas

    1. Take the bus from Detroit Bus Station to Nashville Bus Stationbus
    2. Take the bus from Nashville Bus Station to Dallas Bus Stationbus
    3. Take the bus from Dallas Bus Station to La Plaza at Brownsvillebus
    42h 15m
    $225–436
  3. Train, bus via San Antonio

    1. Take the train from Detroit to Chicago Union Stationtrain
    2. Take the train from Chicago Union Station to San Antonio Amtrak Stationtrain
    3. Take the bus from San Antonio to Brownsvillebus
    46h 26m
    $271–614
  4. Drive 1,645.4 mi

    1. Drive from Detroit to Port Isabelcar1,645.4 mi
    29h 2m
    $301–434
  5. Fly to Mcallen Miller International Airport, bus

    1. Fly from Detroit (DTW) to Mcallen Miller International Airport (MFE)planeDTW - MFE
    2. Take the bus from McAllen Central Station to Brownsvillebus
    11h 46m
    $219–866
  6. Fly to Rio Grande Valley International Airport, bus

    1. Fly from Detroit (DTW) to Rio Grande Valley International Airport (HRL)planeDTW - HRL
    2. Take the bus from Harlingen Bus Station to Brownsvillebus
    12h 25m
    $141–546
  7. Bus

    1. Take the bus from Detroit, MI to Indianapolis, INbus
    2. Take the bus from Indianapolis to Tornado Bus Co - West Memphisbus
    3. Take the bus from Tornado Bus Co - West Memphis to Tornado Bus Co - Laredo, TXbus
    4. Take the bus from Laredo Bus Station to La Plaza at Brownsvillebus
    44h 4m
    $296–637
  8. Train, bus

    1. Take the train from Detroit to Chicago Union Stationtrain
    2. Take the train from Chicago Union Station to San Marcos Amtraktrain
    3. Take the bus from San Marcos to La Plaza at Brownsvillebus
    2d 1h
    $269–523

Detroit (DTW) to Brownsville-South Padre Island International Airport (BRO) flights

Calendar38Weekly Planes
Duration6h 57mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

What companies run services between Detroit, MI, USA and Port Isabel, TX, USA?

American Airlines, United Airlines, and Delta fly from Detroit (DTW) to Brownsville-South Padre Island International Airport (BRO) 5 times a day. Alternatively, you can take a bus from Detroit Bus Station to Las Palmas Port Isabel via Nashville Bus Station, Dallas Bus Station, and La Plaza at Brownsville in around 42h 15m.

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