There are 8 ways to get from Detroit to Panama City by plane, bus, car or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Panama City  •  6 h 10 min

  1. Fly from Detroit (DTW) to Panama City (ECP) DTW - ECP

$252 - $1,027

Cheapest option

Bus  •  27 h 1 min

  1. Take the bus from Detroit, Mi to Atlanta, Ga
  2. Take the bus from Atlanta, Ga to Tallahassee, Fl
  3. Take the bus from Tallahassee, Fl to Panama City, Fl

$123 - $309

6 alternative options

Fly to Tallahassee, bus  •  7 h 26 min

  1. Fly from Detroit (DTW) to Tallahassee (TLH) DTW - TLH
  2. Take the bus from Tallahassee, Fl to Panama City, Fl

$318 - $1,482

Fly to Valparaiso, drive  •  7 h 21 min

  1. Fly from Detroit (DTW) to Valparaiso (VPS) DTW - VPS
  2. Drive from Valparaiso to Panama City

$208 - $1,012

Fly to Pensacola, bus  •  8 h 46 min

  1. Fly from Detroit (DTW) to Pensacola (PNS) DTW - PNS
  2. Take the bus from Pensacola, Fl to Panama City, Fl

$285 - $1,262

Fly to Dothan, drive  •  7 h 35 min

  1. Fly from Detroit (DTW) to Dothan (DHN) DTW - DHN
  2. Drive from Dothan to Panama City

$330 - $1,615

Bus, train  •  34 h 53 min

  1. Take the bus from Detroit, Mi to Toledo, Oh
  2. Take the train from Toledo Amtrak to Washington Union Station Amtrak
  3. Take the train from Washington Union Station Amtrak to Jacksonville Amtrak
  4. Take the bus from Jacksonville, Fl to Tallahassee, Fl
  5. Take the bus from Tallahassee, Fl to Panama City, Fl

$248 - $670

Drive  •  17 h 33 min

  1. Drive from Detroit to Panama City 1005.8 miles

$95 - $150

What companies run services between Detroit, MI, USA and Panama City, FL, USA?

Southwest Airlines, Delta and two other airlines fly from Detroit to Panama City hourly. Alternatively, you can take a bus from Detroit to Panama City via Atlanta, Ga and Tallahassee, Fl in around 27 h 1 min.

Airlines
Delta
Website
delta.com
Flights from Detroit to Panama City via Atlanta
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$300 - $2,200
Flights from Detroit to Panama City via Nashville, Atlanta
Ave. Duration
5 h 23 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $2,200
Flights from Detroit to Tallahassee via Atlanta
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$270 - $1,400
Flights from Detroit to Tallahassee via Grand Rapids, Atlanta
Ave. Duration
5 h 42 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $1,400
Flights from Detroit to Tallahassee via Indianapolis, Atlanta
Ave. Duration
5 h 57 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$280 - $1,400
Flights from Detroit to Valparaiso via Atlanta
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$400 - $2,200
Flights from Detroit to Pensacola via Atlanta
Ave. Duration
4 h 46 min
When
Every day
Estimated price
$250 - $1,200
Flights from Detroit to Dothan via Atlanta
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$320 - $1,600
Flights from Detroit to Dothan via Covington, Atlanta
Ave. Duration
6 h 4 min
When
Saturday
Estimated price
$330 - $1,600
Flights from Detroit to Dothan via Nashville, Atlanta
Ave. Duration
6 h 6 min
When
Every day
Estimated price
$330 - $1,700
Flights from Detroit to Dothan via Lexington, Atlanta
Ave. Duration
6 h 14 min
When
Saturday
Estimated price
$330 - $1,600
Flights from Detroit to Dothan via Greenville/Spartanburg, Atlanta
Ave. Duration
6 h 16 min
When
Every day
Estimated price
$330 - $1,700
Flights from Detroit to Dothan via Grand Rapids, Atlanta
Ave. Duration
6 h 16 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,700
Flights from Detroit to Dothan via Myrtle Beach, Atlanta
Ave. Duration
6 h 21 min
When
Every day
Estimated price
$370 - $1,800
Flights from Detroit to Dothan via St. Louis, Atlanta
Ave. Duration
6 h 21 min
When
Saturday
Estimated price
$370 - $1,800
Flights from Detroit to Dothan via Cleveland, Atlanta
Ave. Duration
6 h 22 min
When
Sunday
Estimated price
$330 - $1,700
Flights from Detroit to Dothan via Reagan Washington, Atlanta
Ave. Duration
6 h 23 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$370 - $1,800
Flights from Detroit to Dothan via Milwaukee, Atlanta
Ave. Duration
6 h 30 min
When
Monday to Friday
Estimated price
$370 - $1,700
American Airlines
Website
aa.com
Flights from Detroit to Panama City via Charlotte
Ave. Duration
5 h 2 min
When
Every day
Estimated price
$320 - $1,500
Flights from Detroit to Panama City via Dallas/Ft.Worth
Ave. Duration
7 h 46 min
When
Every day
Estimated price
$410 - $1,700
Flights from Detroit to Tallahassee via Charlotte
Ave. Duration
5 h 51 min
When
Every day
Estimated price
$300 - $1,400
Flights from Detroit to Tallahassee via Reagan Washington
Ave. Duration
5 h 25 min
When
Monday to Friday
Estimated price
$330 - $1,500
Flights from Detroit to Tallahassee via Miami
Ave. Duration
6 h 30 min
When
Every day
Estimated price
$380 - $1,600
Flights from Detroit to Tallahassee via Dallas/Ft.Worth
Ave. Duration
8 h 36 min
When
Every day
Estimated price
$400 - $1,600
Flights from Detroit to Valparaiso via Charlotte
Ave. Duration
5 h 28 min
When
Every day
Estimated price
$450 - $2,400
Flights from Detroit to Valparaiso via Reagan Washington
Ave. Duration
5 h 15 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$450 - $2,400
Flights from Detroit to Valparaiso via Dallas/Ft.Worth
Ave. Duration
6 h 54 min
When
Every day
Estimated price
$450 - $2,400
Flights from Detroit to Pensacola via Charlotte
Ave. Duration
5 h 16 min
When
Every day
Estimated price
$280 - $1,300
Flights from Detroit to Pensacola via Reagan Washington
Ave. Duration
6 h 27 min
When
Every day
Estimated price
$300 - $1,300
Flights from Detroit to Pensacola via Dallas/Ft.Worth
Ave. Duration
6 h 4 min
When
Every day
Estimated price
$340 - $1,400
Flights from Detroit to Pensacola via Philadelphia
Ave. Duration
5 h 52 min
When
Tuesday and Saturday
Estimated price
$320 - $1,400
Flights from Detroit to Pensacola via Miami
Ave. Duration
6 h 53 min
When
Every day
Estimated price
$350 - $1,400
Southwest Airlines
Website
southwest.com
Flights from Detroit to Panama City via Nashville
Ave. Duration
4 h 51 min
When
Saturday and Sunday
Estimated price
$310 - $2,300
Flights from Detroit to Panama City via Chicago Midway
Ave. Duration
5 h 10 min
When
Saturday
Estimated price
$310 - $2,300
Flights from Detroit to Panama City via Baltimore
Ave. Duration
7 h 1 min
When
Every day
Estimated price
$310 - $2,300
Flights from Detroit to Panama City via St. Louis
Ave. Duration
6 h 55 min
When
Saturday
Estimated price
$310 - $2,300
Flights from Detroit to Panama City via Chicago Midway, Nashville
Ave. Duration
5 h 35 min
When
Sunday
Estimated price
$310 - $2,300
Flights from Detroit to Pensacola via Nashville
Ave. Duration
4 h 37 min
When
Saturday and Sunday
Estimated price
$290 - $1,200
Flights from Detroit to Pensacola via St. Louis
Ave. Duration
4 h 20 min
When
Saturday
Estimated price
$310 - $1,300
United Airlines
Website
united.com
Flights from Detroit to Panama City via Houston
Ave. Duration
6 h 49 min
When
Every day
Estimated price
$300 - $3,500
Flights from Detroit to Valparaiso via Houston
Ave. Duration
7 h 59 min
When
Every day
Estimated price
$500 - $3,100
Flights from Detroit to Pensacola via Chicago O'Hare
Ave. Duration
4 h 51 min
When
Every day
Estimated price
$300 - $1,400
Flights from Detroit to Pensacola via Houston
Ave. Duration
6 h 37 min
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$340 - $1,500
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Toledo Amtrak to Washington Union Station Amtrak
Ave. Duration
13 h 16 min
Frequency
Once daily
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $120
Flexi Coach Seat
$140 - $210
Business Coach Seat
$160 - $230
Room
$340 - $470
Train from Washington Union Station Amtrak to Jacksonville Amtrak
Ave. Duration
13 h 44 min
Frequency
3 times a day
Estimated price
$100 - $300
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$180 - $270
Business Coach Seat
$210 - $300
Room
$420 - $600
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tallahassee, Fl to Panama City, Fl
Ave. Duration
1 h 15 min
Frequency
Every 15 minutes
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Pensacola, Fl to Panama City, Fl
Ave. Duration
2 h 40 min
Frequency
Every 30 minutes
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40
Bus from Detroit, Mi to Atlanta, Ga
Ave. Duration
18 h 15 min
Frequency
Hourly
Estimated price
$75 - $190
Website
greyhound.com
Economy
$75 - $130
Flexible
$140 - $190
Bus from Atlanta, Ga to Tallahassee, Fl
Ave. Duration
6 h 25 min
Frequency
Every 2 hours
Estimated price
$30 - $80
Website
greyhound.com
Economy
$30 - $50
Flexible
$60 - $80
Bus from Detroit, Mi to Toledo, Oh
Ave. Duration
1 h 10 min
Frequency
Every 15 minutes
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28
Bus from Jacksonville, Fl to Tallahassee, Fl
Ave. Duration
2 h 40 min
Frequency
Hourly
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50

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Questions & Answers

The distance between Detroit and Panama City is 1373 km. The road distance is 1609 km.

The cheapest way to get from Detroit to Panama City is to drive which costs $95 - $150 and takes 17 h 33 min.

The quickest way to get from Detroit to Panama City is to fly which takes 6 h 10 min and costs $250 - $1,100.

No, there is no direct bus from Detroit to Panama City. However, there are services departing from Detroit, Mi and arriving at Panama City, Fl via Atlanta, Ga and Tallahassee, Fl. The journey, including transfers, takes approximately 27 h 1 min.

It takes approximately 6 h 10 min to get from Detroit to Panama City, including transfers.