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How to get fromDetroit to OFallonby plane, train (Amtrak), bus (Greyhound), car, bus, or bus (Flixbus)

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There are 7 ways to get from Detroit to OFallon by plane, train (Amtrak), bus (Greyhound), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Detroit

    best
    1. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    3h 56m
    $292–662

  2. Drive 543.1 mi

    cheapest
    1. Drive from Detroit to OFalloncar car 543.1 mi
    9h 20m
    $100–144

  3. Train (Amtrak)

    1. Take the train from Detroit to Chicago Union Stationtrain train Wolverine
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    12h
    $213–415

  4. Bus (Greyhound)

    1. Take the bus from Detroit Bus Station to Indianapolis Union Stationbus bus Greyhound US0112
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    13h 33m
    $118–210

  5. Drive to Capital Region International Airport, fly

    1. Drive from Detroit to Lansing-Airport-LANcar car
    2. Fly from Capital Region International Airport (LAN) to Lambert–St. Louis International Airport (STL)plane plane LAN - STL
    5h 33m
    $197–934

  6. Bus to Cleveland-Hopkins International Airport, fly

    1. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    6h 13m
    $189–863

  7. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from Detroit Bus Station to Chicagobus bus FlixBus 2552
    2. Take the bus from Chicago to St Louis Bus Stationbus bus FlixBus N2521
    16h 25m
    $119–189

Detroit (DTW) to Lambert–St. Louis International Airport (STL) flights

Calendar52Weekly Planes
Duration2h 4mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

What companies run services between Detroit, MI, USA and OFallon, MO, USA?

Delta and Southwest Airlines fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a train from Detroit to OFallon via Chicago Union Station, St. Louis, CIVIC CENTER station, and LAMBERT AIRPORT TERMINAL #1 station in around 12h.

Airlines
Train operators
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Need to know: Greyhound

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