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How to get fromDetroit to OFallonby plane, train (Amtrak), bus (Greyhound), car, bus or bus (Flixbus)

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There are 7 ways to get from Detroit to OFallon by plane, train (Amtrak), bus (Greyhound), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Detroit

    best
    1. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    4h 1m
    $252–502

  2. Drive 543.1 mi

    cheapest
    1. Drive from Detroit to OFalloncar car 543.1 mi
    9h 20m
    $100–144

  3. Train (Amtrak)

    1. Take the train from Detroit to Chicago Union Stationtrain train Wolverine
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    12h
    $125–259

  4. Bus (Greyhound)

    1. Take the bus from Detroit Bus Station to Dayton Trotwood Bus Stationbus bus Greyhound US0110
    2. Take the bus from Dayton Trotwood Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    16h 3m
    $106–193

  5. Drive to Capital Region International Airport, fly

    1. Drive from Detroit to Lansing-Airport-LANcar car
    2. Fly from Capital Region International Airport (LAN) to Lambert–St. Louis International Airport (STL)plane plane LAN - STL
    5h 50m
    $207–984

  6. Bus to Cleveland-Hopkins International Airport, fly

    1. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    7h 6m
    $263–507

  7. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from Detroit Bus Station to Chicagobus bus FlixBus 2552
    2. Take the bus from Chicago to St Louis Bus Stationbus bus FlixBus N2521
    16h 24m
    $121–190

Detroit (DTW) to Lambert–St. Louis International Airport (STL) flights

Calendar54Weekly Planes
Duration2h 58mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

What companies run services between Detroit, MI, USA and OFallon, MO, USA?

Delta, Southwest Airlines, and two other airlines fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a train from Detroit to OFallon via Chicago Union Station, St. Louis, CIVIC CENTER station, and LAMBERT AIRPORT TERMINAL #1 station in around 12h.

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Need to know: Greyhound

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