There are 5 ways to get from Detroit to Knoxville by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville  •  3 h 40 min

  1. Fly from Detroit (DTW) to Knoxville (TYS) DTW - TYS

$257 - $772

Cheapest option

Bus  •  11 h 12 min

  1. Take the bus from Detroit, Mi to Cincinnati, Oh 1105 / ...
  2. Take the bus from Cincinnati, Oh to Knoxville, Tn 1109 / ...

$60 - $148

3 alternative options

Fly to Chattanooga, bus  •  6 h 3 min

  1. Fly from Detroit (DTW) to Chattanooga (CHA) DTW - CHA
  2. Take the bus from Chattanooga, Tn to Knoxville, Tn

$198 - $992

Bus Barons Bus  •  14 h 53 min

  1. Take the bus from Detroit, MI to Cincinnati, OH Schedules 0014 and 0015
  2. Take the bus from Cincinnati, Oh to Knoxville, Tn 1109 / ...

$64 - $138

Drive  •  8 h 42 min

  1. Drive from Detroit to Knoxville 516.5 miles

$50 - $75

Questions & Answers

The cheapest way to get from Detroit to Knoxville is to drive which costs $50 - $75 and takes 8 h 42 min.

More details

The quickest way to get from Detroit to Knoxville is to fly which costs $250 - $800 and takes 3 h 40 min.

More details

The distance between Detroit and Knoxville is 445 miles. The road distance is 516.5 miles.

Get driving directions

It takes approximately 3 h 40 min to get from Detroit to Knoxville, including transfers.

More details

No, there is no direct bus from Detroit to Knoxville. However, there are services departing from Detroit, Mi and arriving at Knoxville, Tn via Cincinnati, Oh. The journey, including transfers, takes approximately 11 h 12 min.

More details

What companies run services between Detroit, MI, USA and Knoxville, TN, USA?

Delta, American Airlines and United Airlines fly from Detroit to Knoxville every 2 hours. Alternatively, you can take a bus from Detroit to Knoxville via Cincinnati, Oh in around 11 h 12 min.

Airlines
Delta
Website
delta.com
Flights from Detroit to Knoxville
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$360 - $1,600
Flights from Detroit to Knoxville via Atlanta
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$360 - $1,600
Flights from Detroit to Chattanooga
Ave. Duration
1 h 47 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $950
Flights from Detroit to Chattanooga via Atlanta
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$190 - $1,000
American Airlines
Website
aa.com
Flights from Detroit to Knoxville via Charlotte
Ave. Duration
3 h 49 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$370 - $1,600
Flights from Detroit to Knoxville via Chicago O'Hare
Ave. Duration
4 h 1 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$370 - $1,600
Flights from Detroit to Chattanooga via Charlotte
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$210 - $1,000
United Airlines
Website
united.com
Flights from Detroit to Knoxville via Washington Dulles
Ave. Duration
3 h 51 min
When
Monday to Saturday
Estimated price
$380 - $1,500
Flights from Detroit to Knoxville via Chicago O'Hare
Ave. Duration
4 h 4 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$380 - $1,500
Flights from Detroit to Chattanooga via Washington Dulles
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$240 - $1,100
Flights from Detroit to Chattanooga via Chicago O'Hare
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$220 - $1,100
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Chattanooga, Tn to Knoxville, Tn
Ave. Duration
1 h 55 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Bus from Detroit, Mi to Cincinnati, Oh
Ave. Duration
5 h 40 min
Frequency
Hourly
Estimated price
$30 - $75
Website
greyhound.com
Economy
$30 - $50
Flexible
$55 - $75
Bus from Cincinnati, Oh to Knoxville, Tn
Ave. Duration
5 h 20 min
Frequency
Every 30 minutes
Estimated price
$29 - $75
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $75

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