There are 4 ways to get from Detroit to Knoxville by plane, taxi, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly, taxi  •  3 h 43 min

  1. Fly from Detroit (DTW) to Knoxville (TYS) DTW - TYS
  2. Take a taxi from Knoxville to Knoxville

$257 - $772

Cheapest option

Bus, Megabus  •  17 h 56 min

  1. Take the bus from Detroit, Mi to Nashville, Tn
  2. Take the bus from Nashville, TN to Chattanooga
  3. Take the Megabus from Chattanooga to Knoxville

$81 - $180

2 alternative options

Bus, train, Megabus  •  27 h 47 min

  1. Take the bus from Detroit, Mi to Toledo, Oh
  2. Take the train from Toledo Amtrak to Washington Union Station Amtrak
  3. Take the train from Washington Union Station Amtrak to Roanoke Amtrak
  4. Take the bus from Campbell Court to Exit 118 Park and Ride
  5. Take the Megabus from Christiansburg to Knoxville

$196 - $497

Drive  •  8 h 42 min

  1. Drive from Detroit to Knoxville 516.5 miles

$50 - $75

What companies run services between Detroit, MI, USA and Knoxville, TN, USA?

You can take a bus from Detroit to Knoxville via Nashville, Tn, Nashville, TN, and Chattanooga in around 17 h 56 min.

Airlines
Delta
Website
delta.com
Flights from Detroit to Knoxville
Ave. Duration
1 h 36 min
When
Every day
Estimated price
$360 - $1,600
Flights from Detroit to Knoxville via Atlanta
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$360 - $1,600
United Airlines
Website
united.com
Flights from Detroit to Knoxville via Washington Dulles
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$380 - $1,500
American Airlines
Website
aa.com
Flights from Detroit to Knoxville via Charlotte
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$370 - $1,600
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Toledo Amtrak to Washington Union Station Amtrak
Ave. Duration
13 h 16 min
Frequency
Once daily
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $120
Flexi Coach Seat
$140 - $210
Business Coach Seat
$160 - $230
Room
$340 - $470
Amtrak Northeast Regional
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Washington Union Station Amtrak to Roanoke Amtrak
Ave. Duration
5 h 5 min
Frequency
Twice daily
Estimated price
$80 - $200
Website
amtrak.com
Coach Seat
$80 - $140
Business Seat
$120 - $200
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Detroit, Mi to Nashville, Tn
Ave. Duration
10 h 55 min
Frequency
Hourly
Estimated price
$50 - $140
Website
greyhound.com
Economy
$50 - $90
Flexible
$100 - $140
Bus from Detroit, Mi to Toledo, Oh
Ave. Duration
1 h 10 min
Frequency
Every 15 minutes
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Nashville, TN to Chattanooga
Ave. Duration
2 h 37 min
Frequency
Twice daily
Estimated price
$14 - $25
Schedules at
us.megabus.com
Bus from Chattanooga to Knoxville
Ave. Duration
2 h
Frequency
Twice daily
Estimated price
$12 - $22
Schedules at
us.megabus.com
Bus from Christiansburg to Knoxville
Ave. Duration
4 h
Frequency
3 times a day
Estimated price
$22 - $35
Schedules at
us.megabus.com
Valley Metro Roanoke
Website
valleymetro.com
Bus from Campbell Court to Exit 118 Park and Ride
Ave. Duration
55 min
Frequency
Hourly
Estimated price
$1 - $4
Schedules at
valleymetro.com
Other operators
Taxi from Knoxville to Knoxville
Ave. Duration
18 min
Estimated price
$55 - $70
Knoxville Taxi Service
Phone
+1 865 691 1900
Website
knoxvilletaxicab.com

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Questions & Answers

How far is it from Detroit to Knoxville?

The distance between Detroit and Knoxville is 712 km. The road distance is 826 km.

What is the cheapest way to get from Detroit to Knoxville?

The cheapest way to get from Detroit to Knoxville is to drive which costs $50 - $75 and takes 8 h 42 min.

What is the fastest way to get from Detroit to Knoxville?

The quickest way to get from Detroit to Knoxville is to fly and taxi which takes 3 h 43 min and costs $250 - $800.

Is there a direct bus between Detroit and Knoxville?

No, there is no direct bus from Detroit to Knoxville. However, there are services departing from Detroit, Mi and arriving at Knoxville via Nashville, TN and Chattanooga. The journey, including transfers, takes approximately 17 h 56 min.

How long does it take to get from Detroit to Knoxville?

It takes approximately 3 h 43 min to get from Detroit to Knoxville, including transfers.