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There are 4 ways to get from Detroit to Great Smoky Mountains by plane, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, drive  •  5 h 26 min

  1. Fly from Detroit (DTW) to Knoxville (TYS) DTW - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$208 - $712

Cheapest option

Bus, drive  •  21 h 58 min

  1. Take the bus from Detroit, Mi to Winston Salem, Nc
  2. Take the bus from Winston Salem, Nc to Asheville, Nc
  3. Drive from Asheville, Nc to Great Smoky Mountains

$89 - $215

2 alternative options

Fly to Greenville/Spartanburg, drive  •  6 h 57 min

  1. Fly from Detroit (DTW) to Greenville/Spartanburg (GSP) DTW - GSP
  2. Drive from Greenville/Spartanburg to Great Smoky Mountains

$175 - $822

Drive  •  10 h 26 min

  1. Drive from Detroit to Great Smoky Mountains 581.1 miles

$55 - $85

Questions & Answers

The cheapest way to get from Detroit to Great Smoky Mountains is to drive which costs $55 - $85 and takes 10 h 26 min.

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The quickest way to get from Detroit to Great Smoky Mountains is to fly and drive which costs $200 - $750 and takes 5 h 26 min.

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The distance between Detroit and Great Smoky Mountains is 470 miles. The road distance is 581.1 miles.

Get driving directions

It takes approximately 5 h 26 min to get from Detroit to Great Smoky Mountains, including transfers.

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The quickest flight from Detroit Airport to Knoxville Airport is the direct flight which takes 1 h 39 min.

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Yes, the driving distance between Detroit to Great Smoky Mountains is 581 miles. It takes approximately 10 h 26 min to drive from Detroit to Great Smoky Mountains.

Get driving directions

Delta, United Airlines and American Airlines offer flights from Detroit Airport to Knoxville Airport.

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There are 1383+ hotels available in Great Smoky Mountains. Prices start at $62 USD per night.

More details

The best way to get from Detroit to Detroit Airport is to line 261 bus which takes 49 min and costs $2.

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Map of how to get from Detroit to Great Smoky Mountains.
Launch map view
  • Distance: 469.6 miles
  • Duration: 5 h 26 min

What companies run services between Detroit, MI, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Detroit to Great Smoky Mountains. However, you can take the line 261 bus to Metro Airport Mcnamara Terminal, take the walk to Detroit airport, fly to Knoxville, then take the drive to Great Smoky Mountains. Alternatively, you can take the line 261 bus to Metro Airport Mcnamara Terminal, take the walk to Detroit airport, fly to Greenville/Spartanburg, then take the drive to Great Smoky Mountains.

Airlines
Delta
Website
delta.com
Flights from Detroit to Knoxville
Ave. Duration
1 h 46 min
When
Every day
Estimated price
$360 - $1,600
Flights from Detroit to Knoxville via Atlanta
Ave. Duration
4 h 6 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$360 - $1,600
Flights from Detroit to Greenville/Spartanburg
Ave. Duration
2 h 2 min
When
Every day
Estimated price
$280 - $1,600
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 24 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,600
American Airlines
Website
aa.com
Flights from Detroit to Knoxville via Charlotte
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$370 - $1,600
Flights from Detroit to Knoxville via Chicago O'Hare
Ave. Duration
4 h 2 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$370 - $1,600
Flights from Detroit to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$300 - $650
Flights from Detroit to Greenville/Spartanburg via Reagan Washington
Ave. Duration
4 h 11 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $650
United Airlines
Website
united.com
Flights from Detroit to Knoxville via Chicago O'Hare
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$380 - $1,500
Flights from Detroit to Knoxville via Washington Dulles
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$380 - $1,500
Flights from Detroit to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$330 - $1,700
Flights from Detroit to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$330 - $1,700
Southwest Airlines
Website
southwest.com
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 20 min
When
Monday to Friday
Estimated price
$320 - $2,000
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Detroit, Mi to Winston Salem, Nc
Ave. Duration
16 h
Frequency
3 times a day
Estimated price
$60 - $160
Website
greyhound.com
Economy
$60 - $100
Flexible
$110 - $160
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Once daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50

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