Explore 4 ways to travel

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, drive  •  5 h 20 min

  1. Fly from Detroit (DTW) to Knoxville (TYS) DTW - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$208 - $712

Cheapest option

Bus, Megabus, drive  •  19 h 42 min

  1. Take the bus from Detroit, Mi to Nashville, Tn
  2. Take the bus from Nashville, TN to Chattanooga
  3. Take the Megabus from Chattanooga to Knoxville
  4. Drive from Knoxville to Great Smoky Mountains

$87 - $190

4 alternative options

Fly to Greenville/Spartanburg, drive  •  6 h 45 min

  1. Fly from Detroit (DTW) to Greenville/Spartanburg (GSP) DTW - GSP
  2. Drive from Greenville/Spartanburg to Great Smoky Mountains

$175 - $822

Bus, drive  •  21 h 58 min

  1. Take the bus from Detroit, Mi to Winston Salem, Nc
  2. Take the bus from Winston Salem, Nc to Asheville, Nc
  3. Drive from Asheville, Nc to Great Smoky Mountains

$89 - $215

Bus, train, Megabus, drive  •  29 h 33 min

  1. Take the bus from Detroit, Mi to Toledo, Oh
  2. Take the train from Toledo Amtrak to Washington Union Station Amtrak
  3. Take the train from Washington Union Station Amtrak to Roanoke Amtrak
  4. Take the bus from Campbell Court to Exit 118 Park and Ride
  5. Take the Megabus from Christiansburg to Knoxville
  6. Drive from Knoxville to Great Smoky Mountains

$202 - $507

Drive  •  10 h 26 min

  1. Drive from Detroit to Great Smoky Mountains 581.1 miles

$55 - $85

What companies run services between Detroit, MI, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Detroit to Great Smoky Mountains. However, you can take the line 261 bus to Metro Airport Mcnamara Terminal, take the walk to Detroit airport, fly to Knoxville, then take the drive to Great Smoky Mountains. Alternatively, you can take the line 261 bus to Metro Airport Mcnamara Terminal, take the walk to Detroit airport, fly to Greenville/Spartanburg, then take the drive to Great Smoky Mountains.

Airlines
Delta
Website
delta.com
Flights from Detroit to Knoxville
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$360 - $1,600
Flights from Detroit to Knoxville via Atlanta
Ave. Duration
4 h 1 min
When
Saturday and Sunday
Estimated price
$360 - $1,600
Flights from Detroit to Greenville/Spartanburg
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$280 - $1,600
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$280 - $1,600
American Airlines
Website
aa.com
Flights from Detroit to Knoxville via Charlotte
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$370 - $1,600
Flights from Detroit to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$300 - $650
United Airlines
Website
united.com
Flights from Detroit to Knoxville via Washington Dulles
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$380 - $1,500
Flights from Detroit to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$330 - $1,700
Southwest Airlines
Website
southwest.com
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 50 min
When
Monday to Friday
Estimated price
$320 - $2,000
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Toledo Amtrak to Washington Union Station Amtrak
Ave. Duration
13 h 16 min
Frequency
Once daily
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $120
Flexi Coach Seat
$140 - $210
Business Coach Seat
$160 - $230
Room
$340 - $470
Amtrak Northeast Regional
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Washington Union Station Amtrak to Roanoke Amtrak
Ave. Duration
5 h 5 min
Frequency
Twice daily
Estimated price
$80 - $200
Website
amtrak.com
Coach Seat
$80 - $140
Business Seat
$120 - $200
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Detroit, Mi to Nashville, Tn
Ave. Duration
10 h 55 min
Frequency
Hourly
Estimated price
$50 - $140
Website
greyhound.com
Economy
$50 - $90
Flexible
$100 - $140
Bus from Detroit, Mi to Winston Salem, Nc
Ave. Duration
16 h
Frequency
Hourly
Estimated price
$60 - $160
Website
greyhound.com
Economy
$60 - $100
Flexible
$110 - $160
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Detroit, Mi to Toledo, Oh
Ave. Duration
1 h 10 min
Frequency
Every 15 minutes
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Nashville, TN to Chattanooga
Ave. Duration
2 h 37 min
Frequency
Twice daily
Estimated price
$14 - $25
Schedules at
us.megabus.com
Bus from Chattanooga to Knoxville
Ave. Duration
2 h
Frequency
Twice daily
Estimated price
$12 - $22
Schedules at
us.megabus.com
Bus from Christiansburg to Knoxville
Ave. Duration
4 h
Frequency
3 times a day
Estimated price
$22 - $35
Schedules at
us.megabus.com
Valley Metro Roanoke
Phone
+1 540-982-0305
Website
valleymetro.com
Bus from Campbell Court to Exit 118 Park and Ride
Ave. Duration
55 min
Frequency
Hourly
Estimated price
$1 - $4
Schedules at
valleymetro.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Detroit and Great Smoky Mountains is 751 km. The road distance is 930 km.

The cheapest way to get from Detroit to Great Smoky Mountains is to drive which costs $55 - $85 and takes 10 h 26 min.

The quickest way to get from Detroit to Great Smoky Mountains is to fly and drive which takes 5 h 20 min and costs $200 - $750.

It takes approximately 5 h 20 min to get from Detroit to Great Smoky Mountains, including transfers.