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How to get fromDestin to San Diegoby plane, taxi, bus, train or car

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There are 7 ways to get from Destin to San Diego by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to San Diego International Airport (SAN)planeVPS - SAN
    7h 6m
    $195–755

  2. Taxi, bus via Los Angeles

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi
    2. Take the bus from McDonald's - Crestview to Houstonbus
    3. Take the bus from Houston to El Pasobus
    4. Take the bus from El Paso to 2474 E Florence Ave - Huntington Parkbus
    5. Take the bus from Huntington Park to San Diegobus
    41h 59m
    $442–799

  3. Taxi, bus, train

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi
    2. Take the bus from McDonald's - Crestview to Houstonbus
    3. Take the train from Houston to Los Angelestrain
    4. Take the train from Los Angeles to San Diegotrain
    2d 5h
    $396–908

  4. Drive 2,029.2 mi

    1. Drive from Destin to San Diegocar2,029.2 mi
    32h
    $371–535

  5. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola International Airport (PNS)taxi
    2. Fly from Pensacola International Airport (PNS) to San Diego International Airport (SAN)planePNS - SAN
    7h 48m
    $300–907

  6. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to San Diego International Airport (SAN)planeECP - SAN
    8h 4m
    $288–854

  7. Taxi, bus

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi
    2. Take the bus from McDonald's - Crestview to Houstonbus
    3. Take the bus from Houston to El Pasobus
    4. Take the bus from El Paso to Cross Border Express, San Diegobus
    46h 32m
    $434–814

Destin–Fort Walton Beach Airport (VPS) to San Diego International Airport (SAN) flights

Calendar33Weekly Planes
Duration8h 11mAverage Duration
Ticket$157Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and San Diego, CA, USA?

Southwest Airlines and American Airlines fly from Destin–Fort Walton Beach Airport (VPS) to San Diego International Airport (SAN) 5 times a day.

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