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How to get fromDestin to Niagara Fallsby plane, bus, taxi, train or car

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There are 11 ways to get from Destin to Niagara Falls by plane, bus, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport, bus

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    6h 23m
    $259–1,335

  2. Fly Destin–Fort Walton Beach Airport to Toronto Pearson International Airport, bus

    cheapest
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Toronto Pearson International Airport (YYZ)plane plane VPS - YYZ
    2. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    8h 9m
    $121–474

  3. Taxi, bus via Nashville

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus
    5. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    33h 41m
    $276–514

  4. Taxi, bus, train

    1. Take the taxi from Destin to Whataburger - Defuniak Springstaxi taxi
    2. Take the bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FLbus bus
    3. Take the bus from Gainesville to Orlando Bus Stationbus bus
    4. Take the train from Orlando to Ny Moynihan Train Hall At Penn Stationtrain train
    5. Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain train
    41h 7m
    $421–936

  5. Drive 1,170.8 mi

    1. Drive from Destin to Niagara Fallscar car 1,170.8 mi
    20h 4m
    $214–309

  6. Taxi to Northwest Florida Beaches International Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)plane plane ECP - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    7h 6m
    $342–1,334

  7. Taxi to Pensacola International Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    7h 28m
    $384–1,537

  8. Fly Destin–Fort Walton Beach Airport to Rochester, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Rochester (ROC)plane plane VPS - ROC
    2. Take the bus from Rochester, NY to Niagara Falls, NYbus bus
    7h 21m
    $193–810

  9. Taxi, bus, train via Jacksonville

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain train
    5. Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain train
    41h 9m

  10. Taxi, bus

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi taxi
    2. Take the bus from McDonald's - Crestview to Circle K - Gainesville, FLbus bus
    3. Take the bus from Gainesville to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Washington Union Stationbus bus
    5. Take the bus from Washington Union Station to Ithacabus bus
    6. Take the bus from Ithaca to Niagara Falls USAbus bus
    42h 6m
    $374–752

  11. Taxi, bus, train #2

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain train
    5. Take the bus from Pittsburgh to Buffalobus bus
    2d

Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) flights

Calendar37Weekly Planes
Duration5h 16mAverage Duration
Ticket$216Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Niagara Falls, NY, USA?

There is no direct connection from Destin to Niagara Falls. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Buffalo Niagara International Airport (BUF), walk to Buffalo Niagara International Airport, then take the bus to Niagara Falls USA. Alternatively, you can take the taxi to Crestview, take the bus to Tallahassee, walk to N Monroe Street and Silver Slipper Lane, take the bus to C.K. Steele Plaza Gate 22, take the bus to Nashville Bus Station, take the bus to Cleveland Bus Station, walk to Cleveland, OH, take the bus to Buffalo, NY, then take the line 40 bus to Main Street & Pine Avenue.

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