There are 10 ways to get from Destin to Natchez by taxi, plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Pensacola International Airport, fly to Natchez
best- Take the taxi from Destin to Pensacola-Airport-PNS
- Fly from Pensacola International Airport (PNS) to Natchez (HEZ)PNS - HEZ
5h 58m$236–637Drive 338.4 mi
cheapest- Drive from Destin to Natchez338.4 mi
6h 53m$62–90Taxi, bus, train, drive
- Take the taxi from Destin to McDonald's - Crestview
- Take the bus from McDonald's - Crestview to Love's Travel Stop - Biloxi
- Take the bus from Biloxi Transit Center to New Orleans Bus Station
- Take the train from New Orleans Union Passenger Terminal to Brookhaven Station
- Drive from Brookhaven Station to Natchez
11h 28m$200–385Fly Destin–Fort Walton Beach Airport to Baton Rouge Metropolitan Airport, drive
- Fly from Destin–Fort Walton Beach Airport (VPS) to Baton Rouge Metropolitan Airport (BTR)VPS - BTR
- Drive from Baton-Rouge-Airport-BTR to Natchez
6h 37m$128–453Fly Destin–Fort Walton Beach Airport to Alexandria International Airport, taxi
- Fly from Destin–Fort Walton Beach Airport (VPS) to Alexandria International Airport (AEX)VPS - AEX
- Take the taxi from Alexandria International Airport (AEX) to Natchez
6h 51m$135–466Fly Destin–Fort Walton Beach Airport to Monroe Regional Airport, taxi
- Fly from Destin–Fort Walton Beach Airport (VPS) to Monroe Regional Airport (MLU)VPS - MLU
- Take the taxi from Monroe Regional Airport (MLU) to Natchez
6h 34m$135–456Fly Destin–Fort Walton Beach Airport to Jackson/Vicksburg, train, drive
- Fly from Destin–Fort Walton Beach Airport (VPS) to Jackson/Vicksburg (JAN)VPS - JAN
- Take the train from Jackson to Brookhaven Station
- Drive from Brookhaven Station to Natchez
7h 38m$156–537Taxi, bus, train, drive via Loxley
- Take the taxi from Destin to McDonald's - Crestview
- Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxley
- Take the bus from Mobile to Biloxi
- Take the bus from Biloxi Transit Center to New Orleans Bus Station
- Take the train from New Orleans Union Passenger Terminal to Brookhaven Station
- Drive from Brookhaven Station to Natchez
11h 47m$240–427Taxi, bus, train, drive via McComb
- Take the taxi from Destin to McDonald's - Crestview
- Take the bus from McDonald's - Crestview to Love's Travel Stop - Biloxi
- Take the bus from Biloxi Transit Center to New Orleans Bus Station
- Take the train from New Orleans Union Passenger Terminal to McComb Station
- Drive from McComb Station to Natchez
11h 59m$189–392Taxi, bus, train, drive #2
- Take the taxi from Destin to McDonald's - Crestview
- Take the bus from McDonald's - Crestview to Baton Rouge Albertson's
- Take the bus from Baton Rouge Park & Ride to New Orleans Bus Station
- Take the train from New Orleans Union Passenger Terminal to McComb Station
- Drive from McComb Station to Natchez
13h 53m$188–378
Pensacola International Airport (PNS) to Natchez (HEZ) flights
Questions & Answers
The cheapest way to get from Destin to Natchez is to drive which costs $60 - $90 and takes 6h 53m.
The fastest way to get from Destin to Natchez is to taxi and fly which takes 5h 58m and costs $230 - $650.
The distance between Destin and Natchez is 318 miles. The road distance is 340.4 miles.
It takes approximately 5h 58m to get from Destin to Natchez, including transfers.
Yes, the driving distance between Destin to Natchez is 340 miles. It takes approximately 6h 53m to drive from Destin to Natchez.
There are 62+ hotels available in Natchez.
What companies run services between Destin, FL, USA and Natchez, MS, USA?
There is no direct connection from Destin to Natchez. However, you can take the taxi to Pensacola-Airport-PNS airport, fly to Natchez (HEZ), then take the taxi to Natchez. Alternatively, you can take the taxi to McDonald's - Crestview, take the bus to Love's Travel Stop - Biloxi, take the taxi to IP Casino, take the bus to Biloxi Transit Center, take the bus to New Orleans Bus Station, walk to New Orleans Union Passenger Terminal, take the train to Brookhaven Station, then drive to Natchez.
- Website
- aa.com
Flights from Destin–Fort Walton Beach Airport to Baton Rouge Metropolitan Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $85–440
Flights from Destin–Fort Walton Beach Airport to Baton Rouge Metropolitan Airport via Charlotte
- Ave. Duration
- 5h 4m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $90–460
Flights from Destin–Fort Walton Beach Airport to Alexandria International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 40m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $80–420
Flights from Destin–Fort Walton Beach Airport to Monroe Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $80–420
Flights from Destin–Fort Walton Beach Airport to Jackson/Vicksburg via Dallas/Ft.Worth
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $85–440
Flights from Destin–Fort Walton Beach Airport to Jackson/Vicksburg via Charlotte
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $85–440
- Website
- delta.com
Flights from Destin–Fort Walton Beach Airport to Baton Rouge Metropolitan Airport via Atlanta
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $70–380
Flights from Destin–Fort Walton Beach Airport to Alexandria International Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $70–390
Flights from Destin–Fort Walton Beach Airport to Monroe Regional Airport via Atlanta
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $70–380
Flights from Destin–Fort Walton Beach Airport to Jackson/Vicksburg via Atlanta
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $60–360
- Website
- united.com
Flights from Pensacola International Airport to Natchez via Houston
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $80–450
- Website
- southwest.com
Flights from Destin–Fort Walton Beach Airport to Jackson/Vicksburg via Nashville
- Ave. Duration
- 7h 5m
- When
- Monday
- Estimated price
- $70–380
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from New Orleans Union Passenger Terminal to Brookhaven Station
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- $29–70
- Website
- https://www.amtrak.com/home.html
Train from Jackson to Brookhaven Station
- Ave. Duration
- 54 min
- Frequency
- Once daily
- Estimated price
- $7–60
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $16–27
- Coach Seat short notice purchase
- $7–60
- Business - advance purchase
- $9–80
- Business Class
- $16–170
Train from New Orleans Union Passenger Terminal to McComb Station
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $13–70
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $20–35
- Coach Seat short notice purchase
- $13–70
- Business - advance purchase
- $18–120
- Business Class
- $30–190
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from McDonald's - Crestview to Love's Travel Stop - Biloxi
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
Bus from McDonald's - Crestview to Love's Travel Stop - Loxley
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $40–130
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–130
Bus from McDonald's - Crestview to Baton Rouge Albertson's
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $65–170
- Schedules at
- tornadobus.com
- Adults 11-59
- $65–170
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Biloxi Transit Center to New Orleans Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $19–30
- Website
- https://www.greyhound.com/
Bus from Baton Rouge Park & Ride to New Orleans Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $19–25
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Biloxi Transit Center to New Orleans Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- $19–29
- Schedules at
- flixbus.com
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Mobile to Biloxi
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- omnibusexpress.com
- Ave. Duration
- 1h 9m
- Estimated price
- $22–160
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
1 Stop Taxi
- Phone
- +1-318-237-4164
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
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