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How to get fromDestin to Natchezby taxi, plane, bus, train, or car

Find Transport to Natchez

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There are 8 ways to get from Destin to Natchez by taxi, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Pensacola International Airport, fly to Natchez

    best
    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Natchez (HEZ)plane plane PNS - HEZ
    5h 44m
    $226–557

  2. Drive 338.4 mi

    cheapest
    1. Drive from Destin to Natchezcar car 338.4 mi
    6h 35m
    $62–90

  3. Taxi, bus, train, drive

    1. Take the taxi from Destin to Downtown Transfer Stationtaxi taxi
    2. Take the taxi from Blue Angel Pkwy & Gulf Beach Hwy to Mobiletaxi taxi
    3. Take the bus from Mobile to Gulfportbus bus
    4. Take the train from Gulfport, MS to New Orleans, LA - Union Passenger Terminaltrain train
    5. Take the train from New Orleans Union Passenger Terminal to McComb Stationtrain train
    6. Drive from McComb Station to Natchezcar car
    12h 23m
    $346–479

  4. Taxi, bus, train, drive via Pascagoula

    1. Take the taxi from Destin to Downtown Transfer Stationtaxi taxi
    2. Take the taxi from Blue Angel Pkwy & Gulf Beach Hwy to Mobiletaxi taxi
    3. Take the bus from Mobile to Pascagoulabus bus
    4. Take the train from Pascagoula, MS to New Orleans, LA - Union Passenger Terminaltrain train
    5. Take the train from New Orleans Union Passenger Terminal to Brookhaven Stationtrain train
    6. Drive from Brookhaven Station to Natchezcar car
    13h 5m
    $354–507

  5. Taxi to Northwest Florida Beaches International Airport, fly to Natchez

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Natchez (HEZ)plane plane ECP - HEZ
    5h 35m
    $255–618

  6. Fly Destin–Fort Walton Beach Airport to Baton Rouge Metropolitan Airport, drive

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Baton Rouge Metropolitan Airport (BTR)plane plane VPS - BTR
    2. Drive from Baton-Rouge-Airport-BTR to Natchezcar car
    5h 58m
    $128–453

  7. Fly Destin–Fort Walton Beach Airport to Alexandria International Airport, taxi

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Alexandria International Airport (AEX)plane plane VPS - AEX
    2. Take the taxi from Alexandria International Airport (AEX) to Natcheztaxi taxi
    6h 16m
    $140–466

  8. Fly Destin–Fort Walton Beach Airport to Monroe Regional Airport, taxi

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Monroe Regional Airport (MLU)plane plane VPS - MLU
    2. Take the taxi from Monroe Regional Airport (MLU) to Natcheztaxi taxi
    6h 56m
    $135–456

Pensacola International Airport (PNS) to Natchez (HEZ) flights

Calendar13Weekly Planes
Duration5h 10mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

Map of how to get from Destin to Natchez.ExpandLaunch map view
  • Distance: 316.4 mi
  • Duration: 5h 44m

What companies run services between Destin, FL, USA and Natchez, MS, USA?

There is no direct connection from Destin to Natchez. However, you can take the taxi to Pensacola-Airport-PNS airport, fly to Natchez (HEZ), then take the taxi to Natchez. Alternatively, you can take the taxi to Downtown Transfer Station, take the line 58 bus to Blue Angel Pkwy & Gulf Beach Hwy, take the taxi to Mobile, take the bus to Gulfport, walk to Gulfport, MS, take the train to New Orleans, LA - Union Passenger Terminal, take the train to McComb Station, then drive to Natchez.

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