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How to get fromDestin to Myrtle Beachby plane, taxi, bus, train or car

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There are 6 ways to get from Destin to Myrtle Beach by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Myrtle Beach (MYR)plane plane VPS - MYR
    3h 44m
    $108–393

  2. Drive 578.9 mi

    cheapest
    1. Drive from Destin to Myrtle Beachcar car 578.9 mi
    11h 57m
    $106–153

  3. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Jacksonvillebus bus
    4. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    5. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    17h 32m
    $239–324

  4. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Myrtle Beach (MYR)plane plane ECP - MYR
    4h 24m
    $191–492

  5. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Myrtle Beach (MYR)plane plane PNS - MYR
    4h 54m
    $203–545

  6. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    20h 22m
    $221–347

Destin–Fort Walton Beach Airport (VPS) to Myrtle Beach (MYR) flights

Calendar34Weekly Planes
Duration4h 11mAverage Duration
Ticket$57Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Myrtle Beach, SC, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Myrtle Beach (MYR) 5 times a day.

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