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How to get fromDestin to Mattoonby taxi, plane, bus, train, car or shuttle

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There are 11 ways to get from Destin to Mattoon by taxi, plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Pensacola International Airport, fly to Lambert–St. Louis International Airport, bus, train

    best
    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    3. Take the bus from St. Louis to Carbondalebus bus
    4. Take the train from Carbondale to Mattoon Amtrak Stationtrain train
    9h 53m
    $272–912

  2. Drive 730.3 mi

    cheapest
    1. Drive from Destin to Mattooncar car 730.3 mi
    13h 23m
    $134–193

  3. Taxi, bus, train via Nashville

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    5. Take the train from Carbondale to Mattoon Amtrak Stationtrain train
    22h 35m
    $240–374

  4. Taxi, bus, train

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi taxi
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Biloxibus bus
    3. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus bus
    4. Take the train from New Orleans Union Passenger Terminal to Mattoon Amtrak Stationtrain train
    23h 26m
    $228–528

  5. Taxi to Northwest Florida Beaches International Airport, fly to Lambert–St. Louis International Airport, bus, train

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    3. Take the bus from St. Louis to Carbondalebus bus
    4. Take the train from Carbondale to Mattoon Amtrak Stationtrain train
    9h 49m
    $260–809

  6. Fly Destin–Fort Walton Beach Airport to Nashville, bus, train

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Nashville (BNA)plane plane VPS - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the train from Carbondale to Mattoon Amtrak Stationtrain train
    10h 59m
    $144–464

  7. Fly Destin–Fort Walton Beach Airport to Midamerica St. Louis Airport, bus, train

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the train from Carbondale to Mattoon Amtrak Stationtrain train
    9h 26m
    $160–499

  8. Taxi to Pensacola International Airport, fly to Nashville, bus, train

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Nashville (BNA)plane plane PNS - BNA
    3. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    4. Take the train from Carbondale to Mattoon Amtrak Stationtrain train
    11h 41m
    $339–546

  9. Fly Destin–Fort Walton Beach Airport to Indianapolis, shuttle, train

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Indianapolis (IND)plane plane VPS - IND
    2. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    3. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Mattoon Amtrak Stationtrain train
    12h 54m
    $196–650

  10. Fly Destin–Fort Walton Beach Airport to Peoria International Airport, bus, train

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Peoria International Airport (PIA)plane plane VPS - PIA
    2. Take the bus from Peoria Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to Champaign Intermodal Trans Ctrbus bus
    4. Take the train from Champaign-Urbana to Mattoon Amtrak Stationtrain train
    10h 35m

  11. Taxi, bus, train via Atlanta

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Champaign Intermodal Trans Ctrbus bus
    5. Take the train from Champaign-Urbana to Mattoon Amtrak Stationtrain train
    28h 50m
    $254–382

Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL) flights

Calendar20Weekly Planes
Duration3h 42mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Mattoon, IL, USA?

There is no direct connection from Destin to Mattoon. However, you can take the taxi to Pensacola-Airport-PNS airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, take the train to CIVIC CENTER station, walk to St. Louis, take the bus to Carbondale, walk to Carbondale, then take the train to Mattoon Amtrak Station. Alternatively, you can take the taxi to Crestview, take the bus to Tallahassee, walk to N Monroe Street and Silver Slipper Lane, take the bus to C.K. Steele Plaza Gate 22, take the bus to Nashville Bus Station, take the bus to Carbondale Intermodal Station, walk to Carbondale, then take the train to Mattoon Amtrak Station.

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