Rome2Rio

How to get fromDestin to Lexingtonby plane, car, taxi or bus

Find Transport to Lexington

See all options

There are 7 ways to get from Destin to Lexington by plane, car, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Louisville International Airport, drive

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF)plane plane VPS - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    3h 37m
    $142–561

  2. Fly Destin–Fort Walton Beach Airport to Blue Grass Airport, line 3 bus

    cheapest
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Blue Grass Airport (LEX)plane plane VPS - LEX
    2. Take the bus from Transit Center to Centre Parkway @ 1349bus bus
    4h 31m
    $105–402

  3. Taxi, bus

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi taxi
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    3. Take the bus from Mobile to Atlantabus bus
    4. Take the bus from Atlanta Bus Station to Lexington Bus Stopbus bus
    17h 44m
    $286–485

  4. Drive 664.4 mi

    1. Drive from Destin to Lexingtoncar car 664.4 mi
    11h 16m
    $122–176

  5. Taxi to Northwest Florida Beaches International Airport, fly to Blue Grass Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Blue Grass Airport (LEX)plane plane ECP - LEX
    6h 59m
    $188–501

  6. Taxi to Pensacola International Airport, fly to Blue Grass Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Blue Grass Airport (LEX)plane plane PNS - LEX
    7h 8m
    $200–564

  7. Taxi, bus via Tallahassee

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Lexington Bus Stopbus bus
    19h 34m
    $248–374

Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF) flights

Calendar19Weekly Planes
Duration3h 37mAverage Duration
Ticket$87Cheapest Price
See schedules

Questions & Answers

What companies run services between Destin, FL, USA and Lexington, KY, USA?

There is no direct connection from Destin to Lexington. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take the taxi to McDonald's - Crestview, take the bus to Love's Travel Stop - Loxley, take the taxi to Mobile, take the bus to Atlanta, walk to Doraville Station, take the subway to Garnett Station, walk to Atlanta Bus Station, take the bus to Lexington Bus Stop, then take the taxi to Lexington.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Destin

Trips to Lexington

Popular routes