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How to get fromDestin to Lexingtonby plane, car, taxi, or bus

Find Transport to Lexington

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There are 8 ways to get from Destin to Lexington by plane, car, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport, drive

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF)plane plane VPS - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    3h 40m
    $157–671

  2. Fly to Blue Grass Airport

    cheapest
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Blue Grass Airport (LEX)plane plane VPS - LEX
    6h 31m
    $110–422

  3. Taxi, bus, drive

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Louisville Bus Stationbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    22h 35m
    $251–371

  4. Drive  664.4 mi

    1. Drive from Destin to Lexingtoncar car 664.4 mi
    11h 20m
    $122–176

  5. Fly to Covington, drive

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Covington (CVG)plane plane VPS - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    3h 47m
    $168–722

  6. Fly to Mcghee Tyson Airport, drive

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS)plane plane VPS - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Lexingtoncar car
    4h 57m
    $183–800

  7. Fly to Tri-State Airport, drive

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Tri-State Airport (HTS)plane plane VPS - HTS
    2. Drive from Tri-State Airport (HTS) to Lexingtoncar car
    7h 36m
    $139–485

  8. Taxi, bus, drive via Atlanta

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Louisville Bus Stationbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    24h 30m
    $255–381

Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF) flights

Calendar53Weekly Planes
Duration2h 54mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

Map of how to get from Destin to Lexington.ExpandLaunch map view
  • Distance: 628.6 mi
  • Duration: 3h 40m

What companies run services between Destin, FL, USA and Lexington, KY, USA?

Delta and American Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Blue Grass Airport (LEX) every 4 hours.

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