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How to get fromDestin to Key Westby plane, taxi, bus, ferry or car

Find Transport to Key West

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There are 6 ways to get from Destin to Key West by plane, taxi, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW)planeVPS - EYW
    4h 36m
    $129–493

  2. Taxi, bus, ferry

    1. Take the taxi from Destin to Crestviewtaxi
    2. Take the bus from Crestview to Fort Myersbus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry
    16h 33m
    $339–405

  3. Drive 745.5 mi

    1. Drive from Destin to Key Westcar745.5 mi
    14h 40m
    $136–197

  4. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Key West International Airport (EYW)planeECP - EYW
    6h 20m
    $232–642

  5. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi
    2. Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)planePNS - EYW
    5h 28m
    $469–1,015

  6. Taxi, bus

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi
    2. Take the bus from McDonald's - Crestview to Dolphin Mall - Miamibus
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    22h 42m
    $223–388

Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW) flights

Calendar45Weekly Planes
Duration4h 56mAverage Duration
Ticket$79Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Key West, FL, USA?

American Airlines and Delta fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW) every 4 hours.

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