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How to get fromDestin to Key Largoby plane, shuttle, taxi, bus, train or car

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There are 9 ways to get from Destin to Key Largo by plane, shuttle, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Miami International Airport, shuttle

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    4h 18m
    $193–500

  2. Drive 648.4 mi

    cheapest
    1. Drive from Destin to Key Largocar car 648.4 mi
    12h 32m
    $119–171

  3. Taxi, bus, train

    1. Take the taxi from Destin to Whataburger - Defuniak Springstaxi taxi
    2. Take the bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FLbus bus
    3. Take the bus from Gainesville to Orlando RedCoach Stationbus bus
    4. Take the train from Orlando to Miamitrain train
    5. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    15h 47m
    $242–721

  4. Taxi to Pensacola International Airport, fly to Miami International Airport, shuttle

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane plane PNS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    5h 19m
    $388–772

  5. Taxi to Pensacola International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane PNS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    5h 44m
    $328–572

  6. Fly Destin–Fort Walton Beach Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane VPS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    7h 16m
    $218–500

  7. Taxi to Northwest Florida Beaches International Airport, fly to Miami International Airport, shuttle

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Miami International Airport (MIA)plane plane ECP - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    8h 8m
    $296–659

  8. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Miamibus bus
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    18h 2m
    $209–274

  9. Taxi, bus via Homestead

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi taxi
    2. Take the bus from McDonald's - Crestview to Dolphin Mall - Miamibus bus
    3. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    18h 43m
    $205–350

Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA) flights

Calendar7Weekly Planes
Duration1h 38mAverage Duration
Ticket$52Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Key Largo, FL, USA?

There is no direct connection from Destin to Key Largo. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, then take the shuttle to Key Largo, FL. Alternatively, you can take the taxi to Whataburger - Defuniak Springs, take the bus to Circle K - Gainesville, FL, take the taxi to Gainesville, take the bus to Orlando RedCoach Station, take the taxi to Orlando, take the train to Miami, walk to Historic Overtown/Lyric Theatre Stat.Rail Northbound, take the line 2600 train to Miami Airport Station, walk to Miami, Airport Intermodal Station, then take the bus to Key Largo Bus Stop.

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