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How to get fromDestin to Key Largoby plane, shuttle, taxi, bus, train or car

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There are 9 ways to get from Destin to Key Largo by plane, shuttle, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Miami International Airport, shuttle

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)planeVPS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle
    4h 25m
    $173–470

  2. Drive 648.4 mi

    cheapest
    1. Drive from Destin to Key Largocar648.4 mi
    12h 26m
    $119–171

  3. Taxi, bus, train

    1. Take the taxi from Destin to Whataburger - Defuniak Springstaxi
    2. Take the bus from Whataburger - Defuniak Springs to Mi Ranchito Restaurant - Ocala, FLbus
    3. Take the bus from Ocala to Plant Citybus
    4. Take the train from Lakeland to Delray Beach Amtraktrain
    5. Take the train from Delray Beach Station to Miami Airport Stationtrain
    6. Take the bus from Miami Airport Station to Key Largo Bus Stopbus
    17h 8m
    $320–592

  4. Taxi to Pensacola International Airport, fly to Miami International Airport, shuttle

    1. Take the taxi from Destin to Pensacola International Airport (PNS)taxi
    2. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)planePNS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle
    5h 13m
    $368–712

  5. Taxi to Pensacola International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the taxi from Destin to Pensacola International Airport (PNS)taxi
    2. Fly from Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL)planePNS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle
    5h 42m
    $323–532

  6. Fly Destin–Fort Walton Beach Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Fort Lauderdale–Hollywood International Airport (FLL)planeVPS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle
    7h 27m
    $193–460

  7. Taxi to Northwest Florida Beaches International Airport, fly to Miami International Airport, shuttle

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Miami International Airport (MIA)planeECP - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle
    7h 40m
    $276–619

  8. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi
    2. Take the bus from Crestview to Miamibus
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus
    18h 2m
    $207–269

  9. Taxi, bus via Homestead

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi
    2. Take the bus from McDonald's - Crestview to Dolphin Mall - Miamibus
    3. Take the bus from Dolphin Mall to Sw 112 Av @ # 20760bus107
    4. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus301
    18h 43m

Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA) flights

Calendar22Weekly Planes
Duration3h 36mAverage Duration
Ticket$52Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Key Largo, FL, USA?

There is no direct connection from Destin to Key Largo. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, then take the shuttle to Key Largo, FL. Alternatively, you can take the taxi to Whataburger - Defuniak Springs, take the bus to Mi Ranchito Restaurant - Ocala, FL, take the bus to Plant City, take the taxi to Lakeland, take the train to Delray Beach Amtrak, take the train to Miami Airport Station, walk to Miami, Airport Intermodal Station, then take the bus to Key Largo Bus Stop.

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