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How to get fromDestin to Des Moinesby plane, taxi, bus, train or car

Find Transport to Des Moines

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There are 7 ways to get from Destin to Des Moines by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Des Moines (DSM)plane plane VPS - DSM
    3h 2m
    $135–481

  2. Taxi, bus via Wake Village

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi taxi
    2. Take the bus from McDonald's - Crestview to Baton Rouge Albertson'sbus bus
    3. Take the bus from Baton Rouge Bus Station to Shreveport Bus Stationbus bus
    4. Take the bus from Shreveport Bus Station to Texarkanabus bus
    5. Take the bus from Texarkana to Kansas Citybus bus
    6. Take the bus from Kansas City to Des Moinesbus bus
    30h 8m
    $255–629

  3. Taxi, bus, train

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi taxi
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Biloxibus bus
    3. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus bus
    4. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    5. Take the bus from Chicago Bus Station to Des Moinesbus bus
    36h 55m
    $438–955

  4. Drive 1,056 mi

    1. Drive from Destin to Des Moinescar car 1,056 mi
    19h 32m
    $193–279

  5. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Des Moines (DSM)plane plane ECP - DSM
    6h 8m
    $223–600

  6. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Des Moines (DSM)plane plane PNS - DSM
    5h 46m
    $240–663

  7. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Indianapolisbus bus
    5. Take the bus from Indianapolis to Chicago Bus Stationbus bus
    6. Take the bus from Chicago Bus Station to Des Moinesbus bus
    36h 22m
    $308–532

Destin–Fort Walton Beach Airport (VPS) to Des Moines (DSM) flights

Calendar15Weekly Planes
Duration4h 17mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Des Moines, IA, USA?

Allegiant Air and Delta fly from Destin–Fort Walton Beach Airport (VPS) to Des Moines (DSM) twice daily.

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