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How to get fromDestin to Clemsonby plane, taxi, bus, train or car

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There are 6 ways to get from Destin to Clemson by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Greenville–Spartanburg International Airport (GSP)planeVPS - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Clemsontaxi
    4h 46m
    $218–630

  2. Drive 422.5 mi

    cheapest
    1. Drive from Destin to Clemsoncar422.5 mi
    8h 34m
    $78–112

  3. Taxi, bus

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus
    3. Take the bus from Mobile to Atlantabus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
    5. Take the taxi from Taqueria Guadalajara - Greenville to Clemsontaxi
    13h 48m
    $324–583

  4. Taxi, bus, train

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Biloxibus
    3. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus
    4. Take the train from New Orleans Union Passenger Terminal to Clemson Amtrak Stationtrain
    23h 15m
    $220–507

  5. Fly to Asheville Regional Airport, drive

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Asheville Regional Airport (AVL)planeVPS - AVL
    2. Drive from Asheville-Airport-AVL to Clemsoncar
    3h 24m
    $106–389

  6. Taxi, bus via Tallahassee

    1. Take the taxi from Destin to Crestviewtaxi
    2. Take the bus from Crestview to Tallahasseebus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
    17h 16m
    $297–502

Destin–Fort Walton Beach Airport (VPS) to Greenville–Spartanburg International Airport (GSP) flights

Calendar48Weekly Planes
Duration4h 49mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Clemson, SC, USA?

There is no direct connection from Destin to Clemson. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Clemson. Alternatively, you can take the taxi to McDonald's - Crestview, take the bus to Love's Travel Stop - Loxley, take the taxi to Mobile, take the bus to Atlanta, walk to Doraville Station, take the line 133 bus to Shallowford Rd @ New Peachtree Rd, walk to Atlanta, take the bus to Taqueria Guadalajara - Greenville, then take the taxi to Clemson.

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