There are 4 ways to get from Destin to Clemson by plane, taxi, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Greenville–Spartanburg International Airport, taxi
best- Fly from Destin–Fort Walton Beach Airport (VPS) to Greenville–Spartanburg International Airport (GSP)plane VPS - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Clemsontaxi
4h 43m$223–630Drive 422.5 mi
cheapest- Drive from Destin to Clemsoncar 422.5 mi
8h 36m$78–112Taxi, bus
- Take the taxi from Destin to Crestviewtaxi
- Take the bus from Crestview to Tallahasseebus
- Take the bus from Tallahassee to Atlanta Bus Stationbus
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Clemsontaxi
15h 13m$324–540Fly to Asheville Regional Airport, drive
- Fly from Destin–Fort Walton Beach Airport (VPS) to Asheville Regional Airport (AVL)plane VPS - AVL
- Drive from Asheville-Airport-AVL to Clemsoncar
3h 25m$106–399
Destin–Fort Walton Beach Airport (VPS) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Destin to Clemson is to drive which costs $75 - $120 and takes 8h 36m.
The fastest way to get from Destin to Clemson is to fly and drive which takes 3h 25m and costs $100 - $400.
The distance between Destin and Clemson is 455 miles. The road distance is 424.9 miles.
The best way to get from Destin to Clemson without a car is to taxi and bus which takes 15h 13m and costs $320 - $550.
It takes approximately 4h 43m to get from Destin to Clemson, including transfers.
Clemson is 1h ahead of Destin. It is currently 8:19 AM in Destin and 9:19 AM in Clemson.
Yes, the driving distance between Destin to Clemson is 425 miles. It takes approximately 8h 36m to drive from Destin to Clemson.
There are 106+ hotels available in Clemson.
What companies run services between Destin, FL, USA and Clemson, SC, USA?
There is no direct connection from Destin to Clemson. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Clemson. Alternatively, you can take the taxi to Crestview, take the bus to Tallahassee, walk to N Monroe Street and Silver Slipper Lane, take the bus to C.K. Steele Plaza Gate 22, take the bus to Atlanta Bus Station, walk to Garnett Station, take the subway to Doraville Station, walk to Atlanta, take the bus to Flying J - Commerce, then take the taxi to Clemson.
- Website
- delta.com
Flights from Destin–Fort Walton Beach Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $70–430
Flights from Destin–Fort Walton Beach Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $50–330
- Website
- southwest.com
Flights from Destin–Fort Walton Beach Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 23m
- When
- Saturday, Sunday, Tuesday, and Wednesday
- Estimated price
- $95–500
Flights from Destin–Fort Walton Beach Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 5h 30m
- When
- Tuesday to Friday
- Estimated price
- $150–700
- Website
- aa.com
Flights from Destin–Fort Walton Beach Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $80–470
Flights from Destin–Fort Walton Beach Airport to Greenville–Spartanburg International Airport via Miami
- Ave. Duration
- 4h 42m
- When
- Saturday
- Estimated price
- $140–650
- Website
- allegiantair.com
Flights from Destin–Fort Walton Beach Airport to Asheville Regional Airport
- Ave. Duration
- 1h 25m
- When
- Sunday and Thursday
- Estimated price
- $50–330
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Crestview to Tallahassee
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- omnibusexpress.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Tallahassee to Atlanta Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tallahassee to Atlanta Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
- Ave. Duration
- 52 min
- Estimated price
- $80–150
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Personal Touch Transportation
- Phone
- +18645250420
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Checker Cab
- Phone
- +1 864-583-2721
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
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