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There are 6 ways to get from Destin to Charleston by plane, taxi, bus, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Valparaiso  •  4 h 32 min

  1. Fly from Valparaiso (VPS) to Charleston (CHS) VPS - CHS

$288 - $1,275

Cheapest option

Taxi, bus, night bus  •  19 h 8 min

  1. Take a taxi from Destin to Pensacola, Fl
  2. Take the bus from Pensacola, Fl to Tallahassee, Fl
  3. Take the night bus from Tallahassee, Fl to Jacksonville, Fl
  4. Take the bus from Jacksonville, Fl to Savannah, Ga
  5. Take the bus from Savannah, GA to Charleston, SC

$238 - $378

4 alternative options

Taxi to Pensacola, fly  •  5 h 24 min

  1. Take a taxi from Destin to Pensacola
  2. Fly from Pensacola (PNS) to Charleston (CHS) PNS - CHS

$366 - $1,280

Taxi, bus via Atlanta, Ga  •  18 h 58 min

  1. Take a taxi from Destin to Pensacola, Fl
  2. Take the bus from Pensacola, Fl to Mobile, Al
  3. Take the bus from Mobile, Al to Atlanta, Ga
  4. Take the bus from Atlanta, Ga to Madison, GA
  5. Take the bus from Madison, GA to Charleston

$247 - $373

Taxi, bus  •  19 h 28 min

  1. Take a taxi from Destin to Pensacola, Fl
  2. Take the bus from Pensacola, Fl to Tallahassee, Fl
  3. Take the bus from Tallahassee, Fl to Jacksonville, Fl
  4. Take the bus from Jacksonville, Fl to Savannah, Ga
  5. Take the bus from Savannah, GA to Charleston, SC

$238 - $378

Drive  •  9 h 34 min

  1. Drive from Destin to Charleston 565.8 miles

$55 - $80

Questions & Answers

The cheapest way to get from Destin to Charleston is to drive which costs $55 - $80 and takes 9 h 34 min.

More details

The quickest way to get from Destin to Charleston is to fly which costs $280 - $1,300 and takes 4 h 32 min.

More details

The distance between Destin and Charleston is 422 miles. The road distance is 565.8 miles.

Get driving directions

The best way to get from Destin to Charleston without a car is to taxi and bus which takes 18 h 58 min and costs $240 - $380.

More details

It takes approximately 4 h 32 min to get from Destin to Charleston, including transfers.

More details

There is no direct flight from Valparaiso Airport to Charleston Airport. The quickest flight takes 3 h 22 min and has one stopover.

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Charleston is 1 h ahead of Destin. It is currently 6:34 PM in Destin and 7:34 PM in Charleston.

Yes, the driving distance between Destin to Charleston is 566 miles. It takes approximately 9 h 34 min to drive from Destin to Charleston.

Get driving directions

United Airlines, Delta and American Airlines offer flights from Valparaiso Airport to Charleston Airport.

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There are 812+ hotels available in Charleston. Prices start at $90 USD per night.

More details

Map of how to get from Destin to Charleston.
Launch map view
  • Distance: 422.4 miles
  • Duration: 4 h 32 min

What companies run services between Destin, FL, USA and Charleston, SC, USA?

Delta, American Airlines and two other airlines fly from Destin to Charleston hourly.

Airlines
American Airlines
Website
aa.com
Flights from Valparaiso to Charleston via Charlotte
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$250 - $1,200
Flights from Valparaiso to Charleston via Dallas/Ft.Worth
Ave. Duration
6 h 17 min
When
Every day
Estimated price
$350 - $1,400
Flights from Valparaiso to Charleston via Reagan Washington
Ave. Duration
6 h 44 min
When
Saturday
Estimated price
$310 - $1,300
Flights from Pensacola to Charleston via Charlotte
Ave. Duration
4 h 8 min
When
Every day
Estimated price
$240 - $1,200
Flights from Pensacola to Charleston via Miami
Ave. Duration
5 h 16 min
When
Every day
Estimated price
$280 - $1,300
Flights from Pensacola to Charleston via Reagan Washington
Ave. Duration
5 h 6 min
When
Monday to Saturday
Estimated price
$300 - $1,300
Flights from Pensacola to Charleston via Philadelphia
Ave. Duration
5 h 28 min
When
Every day
Estimated price
$320 - $1,400
Flights from Pensacola to Charleston via Dallas/Ft.Worth
Ave. Duration
6 h 15 min
When
Every day
Estimated price
$340 - $1,400
Delta
Website
delta.com
Flights from Valparaiso to Charleston via Atlanta
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$220 - $1,200
Flights from Pensacola to Charleston via Atlanta
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$210 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Pensacola to Charleston via Nashville
Ave. Duration
3 h 35 min
When
Monday to Friday
Estimated price
$280 - $1,200
Flights from Pensacola to Charleston via Houston Hobby Apt
Ave. Duration
6 h 25 min
When
Every day
Estimated price
$360 - $1,400
United Airlines
Website
united.com
Flights from Valparaiso to Charleston via Houston
Ave. Duration
5 h 45 min
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$340 - $1,500
Flights from Pensacola to Charleston via Houston
Ave. Duration
5 h 6 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$320 - $1,400
Flights from Pensacola to Charleston via Chicago O'Hare
Ave. Duration
5 h 58 min
When
Tuesday
Estimated price
$340 - $1,500
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Pensacola, Fl to Mobile, Al
Ave. Duration
2 h 5 min
Frequency
Every 2 hours
Estimated price
$12 - $26
Website
greyhound.com
Economy
$12 - $17
Flexible
$20 - $26
Bus from Mobile, Al to Atlanta, Ga
Ave. Duration
5 h 40 min
Frequency
Every 2 hours
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$65 - $90
Bus from Pensacola, Fl to Tallahassee, Fl
Ave. Duration
6 h 15 min
Frequency
Every 4 hours
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $40
Flexible
$45 - $65
Night bus from Tallahassee, Fl to Jacksonville, Fl
Ave. Duration
2 h 40 min
Frequency
Once daily
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Bus from Jacksonville, Fl to Savannah, Ga
Ave. Duration
3 h 30 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, Ga to Madison, GA
Ave. Duration
1 h 5 min
Frequency
Once daily
Estimated price
$17 - $27
Schedules at
southeasternstages.com
Bus from Madison, GA to Charleston
Ave. Duration
5 h 50 min
Frequency
Once daily
Estimated price
$35 - $55
Schedules at
southeasternstages.com
Bus from Savannah, GA to Charleston, SC
Ave. Duration
2 h
Frequency
Once daily
Estimated price
$21 - $35
Schedules at
southeasternstages.com
Other operators
Taxi from Destin to Pensacola
Ave. Duration
1 h 17 min
Estimated price
$130 - $160
Quickie Taxi
Phone
+1 850-716-6545
Website
quickietaxi.com

Want to know more about travelling around United States

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More Questions & Answers

The best way to get from Destin to Valparaiso Airport is to taxi which takes 25 min and costs $40 - $55.

More details