There are 6 ways to get from Des Moines to Wisconsin by plane, bus, train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Des Moines (DSM) to General Mitchell International Airport (MKE)plane DSM - MKE
3h 54m$97–496Drive 355.5 mi
cheapest- Drive from Des Moines to Milwaukeecar 355.5 mi
6h 25m$65–94Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the train from Chicago Union Station to Milwaukeetrain Hiawatha Service / ...
9h 43m$105–163Bus
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus Greyhound US0150
9h 45m$74–112Bus via Milwaukee Mitchell Airport
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the bus from Chicago Bus Station to Milwaukee Mitchell Airportbus FlixBus 2548 / ...
10h 20m$76–111Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
10h 54m$167–269
Des Moines to Wisconsin by bus, foot, and train
Comparing Your Travel Options
The cheapest way to get from Des Moines to Wisconsin is to drive which costs $65 - $95 and takes 6h 25m.
The fastest way to get from Des Moines to Wisconsin is to fly which takes 3h 54m and costs $95 - $500.
No, there is no direct bus from Des Moines to Wisconsin station. However, there are services departing from Des Moines and arriving at Milwaukee Intermodal Station via Chicago Bus Station. The journey, including transfers, takes approximately 9h 45m.
The distance between Des Moines and Wisconsin is 325 miles. The road distance is 357.6 miles.
The best way to get from Des Moines to Wisconsin without a car is to bus and train which takes 9h 43m and costs $100 - $170.
It takes approximately 3h 54m to get from Des Moines to Wisconsin, including transfers.
Des Moines to Wisconsin bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Wisconsin is to fly which takes 3h 54m and costs $95 - $500. Alternatively, you can bus, which costs $70 - $120 and takes 9h 45m.
Des Moines to Wisconsin bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Des Moines to Wisconsin is 358 miles. It takes approximately 6h 25m to drive from Des Moines to Wisconsin.
What companies run services between Des Moines, IA, USA and Wisconsin, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a bus from Des Moines to Milwaukee Intermodal Station via Chicago Bus Station in around 9h 45m.
- Website
- delta.com
Flights from Des Moines to General Mitchell International Airport via Minneapolis
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $85–550
Flights from Des Moines to General Mitchell International Airport via Atlanta
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $160–750
Flights from Des Moines to General Mitchell International Airport via Detroit
- Ave. Duration
- 5h 43m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- southwest.com
Flights from Des Moines to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 5h 22m
- When
- Saturday to Wednesday
- Estimated price
- $75–480
Flights from Des Moines to General Mitchell International Airport via Nashville
- Ave. Duration
- 6h 25m
- When
- Tuesday and Wednesday
- Estimated price
- $130–650
- Website
- united.com
Flights from Des Moines to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $75–470
- Website
- aa.com
Flights from Des Moines to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $75–470
Flights from Des Moines to General Mitchell International Airport via Charlotte
- Ave. Duration
- 6h 19m
- When
- Saturday
- Estimated price
- $170–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $16–24
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Mitchell Airport
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
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Booking & Getting There
Book your Des Moines to Wisconsin bus tickets online with Omio and FlixBus.
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