There are 4 ways to get from Des Moines to Siesta Key by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)plane DSM - SRQ
4h 1m$121–507Bus
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus
2d 1h$350–542Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Winter Park Amtrak Stationtrain
- Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus
2d 5h$1,009–1,656Drive 1,378.7 mi
- Drive from Des Moines to Siesta Keycar 1,378.7 mi
24h 38m$236–341
Des Moines to Siesta Key by bus
Comparing Your Travel Options
The cheapest way to get from Des Moines to Siesta Key is to drive which costs $230 - $340 and takes 24h 38m.
The fastest way to get from Des Moines to Siesta Key is to fly which takes 4h 1m and costs $120 - $550.
No, there is no direct bus from Des Moines to Siesta Key. However, there are services departing from Des Moines and arriving at Ocean Blvd @ Avenida Madera via Chicago Bus Station, Washington Union Station, Orlando Bus Station and Cattlemen Transit Station. The journey, including transfers, takes approximately 2 days 1h.
The distance between Des Moines and Siesta Key is 1190 miles. The road distance is 1386.7 miles.
The best way to get from Des Moines to Siesta Key without a car is to bus which takes 2 days 1h and costs $350 - $550.
It takes approximately 4h 1m to get from Des Moines to Siesta Key, including transfers.
Des Moines to Siesta Key bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Siesta Key is to fly which takes 4h 1m and costs $120 - $550. Alternatively, you can bus, which costs $350 - $550 and takes 2 days 1h.
Des Moines to Siesta Key bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Siesta Key is 1h ahead of Des Moines. It is currently 1:27 PM in Des Moines and 2:27 PM in Siesta Key.
What companies run services between Des Moines, IA, USA and Siesta Key, FL, USA?
Allegiant Air, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ) 4 times a day. Alternatively, you can take a bus from Des Moines to Ocean Blvd @ Avenida Madera via Chicago Bus Station, Washington Union Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 2d 1h.
- Website
- delta.com
Flights from Des Moines to Sarasota–Bradenton International Airport via Atlanta
- Ave. Duration
- 5h 4m
- When
- Friday, Sunday, Monday, Thursday, and Saturday
- Estimated price
- $100–480
- Website
- southwest.com
Flights from Des Moines to Sarasota–Bradenton International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–480
Flights from Des Moines to Sarasota–Bradenton International Airport via Chicago Midway
- Ave. Duration
- 5h 17m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $110–550
- Website
- allegiantair.com
Flights from Des Moines to Sarasota–Bradenton International Airport
- Ave. Duration
- 2h 47m
- When
- Thursday and Sunday
- Estimated price
- $100–480
- Website
- aa.com
Flights from Des Moines to Sarasota–Bradenton International Airport via Chicago O'Hare
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $110–550
Flights from Des Moines to Sarasota–Bradenton International Airport via Charlotte
- Ave. Duration
- 6h 16m
- When
- Saturday
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Winter Park Amtrak Station
- Ave. Duration
- 37h 59m
- Frequency
- Once daily
- Estimated price
- $900–1,500
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Chicago Bus Station to Washington Union Station
- Ave. Duration
- 16h 35m
- Frequency
- 4 times a day
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Washington Union Station to Orlando Bus Station
- Ave. Duration
- 16h 25m
- Frequency
- 3 times a day
- Estimated price
- $130–210
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 3h 15m
- Frequency
- Every 4 hours
- Estimated price
- $23–35
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 3h 15m
- Frequency
- Every 4 hours
- Estimated price
- $23–35
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Des Moines to Siesta Key is 1387 miles. It takes approximately 24h 38m to drive from Des Moines to Siesta Key.
There are 3316+ hotels available in Siesta Key.






