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How to get fromDes Moines to Siesta Keyby plane, bus (Greyhound, Flixbus), bus, train or car

Find Transport to Siesta Key

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There are 5 ways to get from Des Moines to Siesta Key by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)plane plane DSM - SRQ
    4h 10m
    $230–1,125

  2. Bus

    cheapest
    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    34h 26m
    $214–487

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Winter Park Amtrak Stationtrain train
    3. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2d 4h
    $555–1,265

  4. Drive 1,378.7 mi

    1. Drive from Des Moines to Siesta Keycar car 1,378.7 mi
    24h 38m
    $252–364

  5. Bus, train via Bloomington

    1. Take the bus from Des Moines to Bloomington-Normalbus bus
    2. Take the train from Bloomington-Normal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Tampatrain train
    4. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2d 7h
    $581–1,284

Des Moines to Siesta Key by bus

Calendar7Weekly Buses
Duration34h 26mAverage Duration
Ticket$214Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Siesta Key, FL, USA?

Allegiant Air, Delta, and three other airlines fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ) every 4 hours. Alternatively, you can take a bus from Des Moines to Ocean Blvd @ Avenida Madera via St Louis Bus Station, Atlanta Bus Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 34h 26m.

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