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How to get fromDes Moines to Siesta Keyby plane, bus (Greyhound, Flixbus), bus, train or car

Find Transport to Siesta Key

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There are 5 ways to get from Des Moines to Siesta Key by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)plane plane DSM - SRQ
    4h 12m
    $240–1,125

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2d
    $229–576

  3. Bus, train, Amtrak Thruway

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Tampatrain train
    3. Take the bus from Tampa Union Station to Sarasota Amtrak Bus Stopbus bus
    2d 5h

  4. Drive 1,389.8 mi

    1. Drive from Des Moines to Siesta Keycar car 1,389.8 mi
    24h 12m
    $254–367

  5. Bus, train

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Tampatrain train
    4. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2d 11h
    $263–942

Des Moines to Siesta Key by bus

Calendar5Weekly Buses
Duration2dAverage Duration
Ticket$229Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Siesta Key, FL, USA?

Allegiant Air, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ) 5 times a day. Alternatively, you can take a bus from Des Moines to Ocean Blvd @ Avenida Madera via Chicago Bus Station, Washington Union Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 2d.

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