There are 6 ways to get from Des Moines to Siesta Key by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)DSM - SRQ
4h 1m$200–925Bus via Chicago
cheapest- Take the bus from Des Moines to Chicago Bus Station
- Take the bus from Chicago Train Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Orlando Bus Station
- Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Center
38h 33m$194–460Bus
- Take the bus from Des Moines to Champaign
- Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Orlando Bus Station
- Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Center
37h 36m$219–445Bus, train
- Take the bus from Des Moines to Chicago
- Take the train from Chicago Union Station to Winter Park Amtrak Station
- Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Center
2d 3h$465–864Drive 1,389.8 mi
- Drive from Des Moines to Siesta Key1,389.8 mi
24h$254–367Bus, train, Amtrak Thruway
- Take the bus from Des Moines to Burlington
- Take the bus from Burlington to Galesburg
- Take the train from Galesburg Amtrak Station to Chicago Union Station
- Take the train from Chicago Union Station to Lakeland Amtrak Station
- Take the bus from Lakeland to Bradenton-Ellenton, FL
2d 5h
Des Moines to Siesta Key by bus
Questions & Answers
The cheapest way to get from Des Moines to Siesta Key is to bus via Chicago which costs $190 - $460 and takes 38h 33m.
The fastest way to get from Des Moines to Siesta Key is to fly which takes 4h 1m and costs $200 - $950.
No, there is no direct bus from Des Moines to Siesta Key. However, there are services departing from Des Moines and arriving at Ocean Blvd @ Avenida Madera via Champaign Intermodal Trans Ctr, Atlanta Bus Station, Orlando Bus Station and Cattlemen Transit Station. The journey, including transfers, takes approximately 37h 36m.
The distance between Des Moines and Siesta Key is 1190 miles. The road distance is 1397.9 miles.
The best way to get from Des Moines to Siesta Key without a car is to bus which takes 37h 36m and costs $210 - $450.
It takes approximately 4h 1m to get from Des Moines to Siesta Key, including transfers.
Des Moines to Siesta Key bus services, operated by Burlington Trailways, depart from Des Moines station.
The best way to get from Des Moines to Siesta Key is to fly which takes 4h 1m and costs $200 - $950. Alternatively, you can bus, which costs $210 - $450 and takes 37h 36m.
Des Moines to Siesta Key bus services, operated by Burlington Trailways, arrive at Champaign station.
Siesta Key is 1h ahead of Des Moines. It is currently 6:57 PM in Des Moines and 7:57 PM in Siesta Key.
What companies run services between Des Moines, IA, USA and Siesta Key, FL, USA?
Allegiant Air, Southwest Airlines, and three other airlines fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ) every 4 hours. Alternatively, you can take a bus from Des Moines to Ocean Blvd @ Avenida Madera via Champaign, Champaign Intermodal Trans Ctr, Atlanta Bus Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 37h 36m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- delta.com
Flights from Des Moines to Sarasota–Bradenton International Airport via Atlanta
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $180–900
- Website
- allegiantair.com
Flights from Des Moines to Sarasota–Bradenton International Airport
- Ave. Duration
- 2h 42m
- When
- Monday and Saturday
- Estimated price
- $180–900
- Website
- southwest.com
Flights from Des Moines to Sarasota–Bradenton International Airport via St. Louis
- Ave. Duration
- 5h 5m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $180–900
- Website
- aa.com
Flights from Des Moines to Sarasota–Bradenton International Airport via Charlotte
- Ave. Duration
- 5h 40m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- $200–950
Flights from Des Moines to Sarasota–Bradenton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 49m
- When
- Monday, Thursday, and Sunday
- Estimated price
- $200–950
- Website
- united.com
Flights from Des Moines to Sarasota–Bradenton International Airport via Chicago O'Hare
- Ave. Duration
- 6h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $200–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Winter Park Amtrak Station
- Ave. Duration
- 37h 59m
- Frequency
- Once daily
- Estimated price
- $350–650
- Website
- https://www.amtrak.com/home.html
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $21–70
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Lakeland Amtrak Station
- Ave. Duration
- 40h
- Frequency
- Once daily
- Estimated price
- $150–480
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $150–430
- Coach Seat short notice purchase
- $220–480
- Business - advance purchase
- $310–1,200
- Business Class
- $420–1,100
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Champaign
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–95
- Flexible Fares
- $90–130
Bus from Des Moines to Chicago
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $65–143
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–100
- Flexible Fares
- $90–140
- Saver Fare
- $104
- Flex Fare
- $143
Bus from Des Moines to Burlington
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
Bus from Burlington to Galesburg
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Champaign Intermodal Trans Ctr to Atlanta Bus Station
- Ave. Duration
- 14h 10m
- Frequency
- Once daily
- Estimated price
- $80–140
- Schedules at
- flixbus.com
- Adult
- $80–140
Bus from Atlanta Bus Station to Orlando Bus Station
- Ave. Duration
- 7h 55m
- Frequency
- Every 4 hours
- Estimated price
- $45–90
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $26–45
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to Orlando Bus Station
- Ave. Duration
- 7h 55m
- Frequency
- Once daily
- Estimated price
- $45–130
- Website
- https://www.greyhound.com/
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- 3 times a day
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
Bus from Chicago Train Station to Atlanta Bus Station
- Ave. Duration
- 15h 30m
- Frequency
- Twice daily
- Estimated price
- $75–190
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Lakeland to Bradenton-Ellenton, FL
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Des Moines to Siesta Key is 1398 miles. It takes approximately 24h to drive from Des Moines to Siesta Key.
There are 1951+ hotels available in Siesta Key.










