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How to get fromDes Moines to Siesta Keyby plane, bus (Flixbus, Greyhound), bus, train, car or bus (Greyhound, Flixbus)

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There are 6 ways to get from Des Moines to Siesta Key by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)planeDSM - SRQ
    4h 1m
    $200–925
  2. Bus via Chicago

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus
    2. Take the bus from Chicago Train Station to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to Orlando Bus Stationbus
    4. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus
    38h 33m
    $194–460
  3. Bus

    1. Take the bus from Des Moines to Champaignbus
    2. Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to Orlando Bus Stationbus
    4. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus
    37h 36m
    $219–445
  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus
    2. Take the train from Chicago Union Station to Winter Park Amtrak Stationtrain
    3. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus
    2d 3h
    $465–864
  5. Drive 1,389.8 mi

    1. Drive from Des Moines to Siesta Keycar1,389.8 mi
    24h
    $254–367
  6. Bus, train, Amtrak Thruway

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Lakeland Amtrak Stationtrain
    5. Take the bus from Lakeland to Bradenton-Ellenton, FLbus
    2d 5h

Des Moines to Siesta Key by bus

Calendar7Weekly Buses
Duration37h 36mAverage Duration
Ticket$219Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Siesta Key, FL, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ) every 4 hours. Alternatively, you can take a bus from Des Moines to Ocean Blvd @ Avenida Madera via Champaign, Champaign Intermodal Trans Ctr, Atlanta Bus Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 37h 36m.

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