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How to get fromDes Moines to Santa Rosaby plane, bus (Greyhound, Amtrak), bus, train, car, or subway

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There are 7 ways to get from Des Moines to Santa Rosa by plane, bus (Greyhound, Amtrak), bus, train, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Sonoma County Airport

    best
    1. Fly from Des Moines (DSM) to Sonoma County Airport (STS)plane plane DSM - STS
    6h 40m
    $154–626

  2. Bus

    1. Take the bus from Des Moines to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Sparks Transit Centerbus bus
    3. Take the bus from Sparks Transit Center to Suisun City Bus Stopbus bus
    4. Take the bus from Napa Amtrak Bus Stop to Santa Rosa Amtrak Bus Stopbus bus
    45h 36m
    $293–574

  3. Bus, train

    1. Take the bus from Des Moines to Omaha, NEbus bus
    2. Take the bus from Omaha, NE to Denverbus bus
    3. Take the train from Denver to Martineztrain train
    4. Take the bus from Martinez to Santa Rosa Amtrak Bus Stopbus bus
    2d 1h
    $599–1,145

  4. Drive 1,797.8 mi

    1. Drive from Des Moines to Santa Rosacar car 1,797.8 mi
    27h 39m
    $329–474

  5. Fly to San Francisco International Airport, bus, train

    1. Fly from Des Moines (DSM) to San Francisco International Airport (SFO)plane plane DSM - SFO
    2. Take the bus from San Francisco Airport to Larkspur - dropoffbus bus
    3. Take the train from SMART Larkspur to SMART Santa Rosa Downtowntrain train
    8h 59m
    $201–560

  6. Fly to Oakland International Airport, bus, train

    1. Fly from Des Moines (DSM) to Oakland International Airport (OAK)plane plane DSM - OAK
    2. Take the bus from Oakland International Airport to San Rafaelbus bus
    3. Take the train from SMART San Rafael to SMART Santa Rosa Downtowntrain train
    8h 41m
    $264–1,033

  7. Fly to Norman Y. Mineta San José International Airport, BART, train

    1. Fly from Des Moines (DSM) to Norman Y. Mineta San José International Airport (SJC)plane plane DSM - SJC
    2. Take the subway from Milpitas to El Cerrito Del Nortesubway subway
    3. Take the train from SMART San Rafael to SMART Santa Rosa Downtowntrain train
    10h 16m
    $245–950

Des Moines to Santa Rosa by bus

Calendar14Weekly Buses
Duration45h 36mAverage Duration
Ticket$293Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Santa Rosa.ExpandLaunch map view
  • Distance: 1,565.5 mi
  • Duration: 6h 40m

What companies run services between Des Moines, IA, USA and Santa Rosa, CA, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Sonoma County Airport (STS) twice daily. Alternatively, you can take a bus from Des Moines to Santa Rosa Amtrak Bus Stop via Denver Union Station, Sparks Transit Center, Suisun City Train Depot, and Napa Amtrak Bus Stop in around 45h 36m.

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