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How to get fromDes Moines to Santa Rosaby plane, bus (Greyhound), bus, train, car, or subway

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There are 7 ways to get from Des Moines to Santa Rosa by plane, bus (Greyhound), bus, train, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Sonoma County Airport

    best
    1. Fly from Des Moines (DSM) to Sonoma County Airport (STS)plane plane DSM - STS
    7h 34m
    $125–488

  2. Bus

    1. Take the bus from Des Moines to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Sparks Transit Centerbus bus
    3. Take the bus from Sparks Transit Center to San Francisco Bus Stationbus bus
    4. Take the bus from Fremont St & Mission St to Santa Rosa Transit Mall-Bay N1bus bus 172
    46h 15m
    $364–552

  3. Bus, train

    1. Take the bus from Des Moines to Omaha, NEbus bus
    2. Take the bus from Omaha to Denverbus bus
    3. Take the train from Denver to Martineztrain train
    4. Take the bus from Martinez to Santa Rosa Amtrak Bus Stopbus bus
    2d 1h

  4. Drive  1,797.8 mi

    1. Drive from Des Moines to Santa Rosacar car 1,797.8 mi
    27h 39m
    $308–444

  5. Fly to San Francisco International Airport, bus, train

    1. Fly from Des Moines (DSM) to San Francisco International Airport (SFO)plane plane DSM - SFO
    2. Take the bus from San Francisco Airport to Larkspur - dropoffbus bus
    3. Take the train from SMART Larkspur to SMART Santa Rosa Downtowntrain train
    9h 19m
    $152–362

  6. Fly to Oakland International Airport, bus, train

    1. Fly from Des Moines (DSM) to Oakland International Airport (OAK)plane plane DSM - OAK
    2. Take the bus from Oakland International Airport to San Rafaelbus bus
    3. Take the train from SMART San Rafael to SMART Santa Rosa Downtowntrain train
    9h 11m
    $155–585

  7. Fly to Norman Y. Mineta San José International Airport, BART, train

    1. Fly from Des Moines (DSM) to Norman Y. Mineta San José International Airport (SJC)plane plane DSM - SJC
    2. Take the subway from Milpitas to El Cerrito Del Nortesubway subway
    3. Take the train from SMART San Rafael to SMART Santa Rosa Downtowntrain train
    10h 20m
    $156–652

Des Moines to Santa Rosa by bus

Calendar7Weekly Buses
Duration46h 15mAverage Duration
Ticket$364Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Des Moines to Santa Rosa.ExpandLaunch map view
  • Distance: 1,565.5 mi
  • Duration: 7h 34m

What companies run services between Des Moines, IA, USA and Santa Rosa, CA, USA?

American Airlines, Southwest Airlines, and three other airlines fly from Des Moines (DSM) to Sonoma County Airport (STS) 5 times a day. Alternatively, you can take a bus from Des Moines to Santa Rosa Transit Mall-Bay N1 via Denver Union Station, Sparks Transit Center, San Francisco Bus Station, and Fremont St & Mission St in around 46h 15m.

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Want to know more about travelling around United States

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