There are 5 ways to get from Des Moines to Rochester by plane, bus, train, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Rochester
best- Fly from Des Moines (DSM) to Rochester (ROC)plane DSM - ROC
4h 25m$223–1,140Bus
cheapest- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Cleveland Bus Stationbus
- Take the bus from Cleveland, OH to Buffalo, NYbus
- Take the bus from Buffalo to Rochester Bus Stopbus
21h 40m$105–244Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the train from Chicago Union Station to Rochestertrain Lake Shore Limited
19h 44m$107–261Drive 915.8 mi
- Drive from Des Moines to Rochestercar 915.8 mi
15h 26m$168–242Fly to Buffalo Niagara International Airport, bus
- Fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF)plane DSM - BUF
- Take the bus from Buffalo Niagara International Airport to Rochester Bus Stopbus
6h 15m$363–1,844
Des Moines to Rochester by bus, foot, and train
Questions & Answers
The cheapest way to get from Des Moines to Rochester is to bus and train which costs $100 - $270 and takes 19h 44m.
The fastest way to get from Des Moines to Rochester is to fly which takes 4h 25m and costs $220 - $1,200.
No, there is no direct bus from Des Moines to Rochester. However, there are services departing from Des Moines and arriving at Rochester Bus Stop via Chicago Bus Station, Cleveland, OH and Buffalo. The journey, including transfers, takes approximately 21h 40m.
The distance between Des Moines and Rochester is 838 miles. The road distance is 921.2 miles.
The best way to get from Des Moines to Rochester without a car is to bus and train which takes 19h 44m and costs $100 - $270.
It takes approximately 4h 25m to get from Des Moines to Rochester, including transfers.
Des Moines to Rochester bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Rochester is to fly which takes 4h 25m and costs $220 - $1,200. Alternatively, you can bus, which costs $100 - $250 and takes 21h 40m.
Des Moines to Rochester bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Rochester is 1h ahead of Des Moines. It is currently 11:45 PM in Des Moines and 12:45 AM in Rochester.
What companies run services between Des Moines, IA, USA and Rochester, NY, USA?
Delta, United Airlines, and American Airlines fly from Des Moines (DSM) to Rochester (ROC) every 4 hours. Alternatively, you can take a bus from Des Moines to Rochester Bus Stop via Chicago Bus Station, Cleveland Bus Station, Cleveland, OH, Buffalo, NY, and Buffalo in around 21h 40m.
- Website
- aa.com
Flights from Des Moines to Rochester via Chicago O'Hare
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Des Moines to Rochester via Philadelphia
- Ave. Duration
- 8h 35m
- When
- Every day
- Estimated price
- $250–1,300
Flights from Des Moines to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $430–2,200
Flights from Des Moines to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $330–1,800
Flights from Des Moines to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 8h 34m
- When
- Every day
- Estimated price
- $450–2,200
- Website
- delta.com
Flights from Des Moines to Rochester via Detroit
- Ave. Duration
- 4h 28m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $190–1,100
Flights from Des Moines to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $330–1,800
Flights from Des Moines to Buffalo Niagara International Airport via Minneapolis
- Ave. Duration
- 7h 3m
- When
- Monday, Thursday, and Sunday
- Estimated price
- $380–2,000
- Website
- united.com
Flights from Des Moines to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Des Moines to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $330–1,800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Rochester
- Ave. Duration
- 11h 30m
- Frequency
- Twice daily
- Estimated price
- $65–180
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Website
- https://www.greyhound.com/
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $15–23
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Every 3 hours
- Estimated price
- $15–23
- Schedules at
- flixbus.com
Bus from Buffalo Niagara International Airport to Rochester Bus Stop
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $15–23
- Schedules at
- flixbus.com
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More Questions & Answers
Yes, the driving distance between Des Moines to Rochester is 921 miles. It takes approximately 15h 26m to drive from Des Moines to Rochester.
Book your Des Moines to Rochester bus tickets online with Omio and FlixBus.
There are 144+ hotels available in Rochester.










