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How to get fromDes Moines to Pittsburghby plane, bus, train, bus (Greyhound, Flixbus), car or bus (Flixbus)

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There are 7 ways to get from Des Moines to Pittsburgh by plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Pittsburgh International Airport (PIT)planeDSM - PIT
    5h 10m
    $138–721

  2. Bus via Auburn Gresham

    cheapest
    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the bus from Chicago to Pittsburgh Intermodal StationbusFlixBus N2640
    19h 25m
    $120–274

  3. Bus, train

    1. Take the bus from Des Moines to ChicagobusOmaha
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak StationtrainFloridian
    16h 44m
    $158–343

  4. Bus

    1. Take the bus from Des Moines to ChicagobusOmaha
    2. Take the bus from Chicago Bus Station to Pittsburgh Intermodal StationbusGreyhound US0164
    17h 20m
    $123–273

  5. Drive 776 mi

    1. Drive from Des Moines to Pittsburghcar776 mi
    12h 42m
    $142–205

  6. Bus, train via Des Moines

    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak StationtrainFloridian
    17h 49m
    $146–354

  7. Bus, train via Galesburg

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain
    19h 20m
    $180–412

Des Moines to Pittsburgh by bus, foot, and train

Calendar7Weekly Services
Duration16h 44mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Pittsburgh, PA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to Pittsburgh International Airport (PIT) every 3 hours. Alternatively, you can take a bus from Des Moines to Pittsburgh Intermodal Station via Chicago Bus Station in around 17h 20m.

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