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How to get fromDes Moines to Pittsburghby plane, bus, train, bus (Greyhound, Flixbus) or car

Find Transport to Pittsburgh

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There are 7 ways to get from Des Moines to Pittsburgh by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Pittsburgh International Airport

    best
    1. Fly from Des Moines (DSM) to Pittsburgh International Airport (PIT)plane plane DSM - PIT
    5h 53m
    $148–771

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164
    18h 15m
    $97–201

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    17h 39m
    $117–281

  4. Drive 776 mi

    1. Drive from Des Moines to Pittsburghcar car 776 mi
    12h 51m
    $142–205

  5. Fly to Morgantown Municipal Airport, bus

    1. Fly from Des Moines (DSM) to Morgantown Municipal Airport (MGW)plane plane DSM - MGW
    2. Take the bus from Mountaineer Station to Pittsburgh Greyhoundbus bus
    9h 54m
    $152–765

  6. Fly to Johnstown-Cambria County Airport, train

    1. Fly from Des Moines (DSM) to Johnstown-Cambria County Airport (JST)plane plane DSM - JST
    2. Take the train from Johnstown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    7h 41m
    $171–761

  7. Bus via Auburn Gresham

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    19h 27m
    $107–199

Des Moines to Pittsburgh by bus, foot, and train

Calendar7Weekly Services
Duration17h 39mAverage Duration
Ticket$117Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Pittsburgh, PA, USA?

Delta, United Airlines, and two other airlines fly from Des Moines (DSM) to Pittsburgh International Airport (PIT) hourly. Alternatively, you can take a bus from Des Moines to Pittsburgh Intermodal Station via Chicago Bus Station in around 18h 15m.

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