Rome2Rio

How to get fromDes Moines to Perryvilleby plane, train, taxi, bus or car

Find Transport to Perryville

See all options

There are 8 ways to get from Des Moines to Perryville by plane, train, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport, train, taxi

    best
    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to COLLEGE stationtrain train
    3. Take the taxi from COLLEGE station to Perryvilletaxi taxi
    6h 31m
    $361–1,394
  2. Drive 393.2 mi

    cheapest
    1. Drive from Des Moines to Perryvillecar car 393.2 mi
    7h 46m
    $72–104
  3. Bus, taxi

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Perryvilletaxi taxi
    12h 14m
    $156–298
  4. Bus, train, taxi

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the taxi from COLLEGE station to Perryvilletaxi taxi
    13h 7m
    $221–411
  5. Fly to Cape Girardeau Municipal Airport, taxi

    1. Fly from Des Moines (DSM) to Cape Girardeau Municipal Airport (CGI)plane plane DSM - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Perryvilletaxi taxi
    6h 6m
    $293–1,041
  6. Fly to Williamson County Regional Airport, taxi

    1. Fly from Des Moines (DSM) to Williamson County Regional Airport (MWA)plane plane DSM - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Perryvilletaxi taxi
    5h 58m
    $278–851
  7. Bus, taxi via Carbondale

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St. Louis to Carbondalebus bus
    4. Take the taxi from Carbondale to Perryvilletaxi taxi
    12h 44m
    $179–353
  8. Bus, train, taxi via Cape Girardeau

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Perryvilletaxi taxi
    14h 29m
    $176–373

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar2Weekly Planes
Duration3h 47mAverage Duration
Ticket$201Cheapest Price
See schedules

Questions & Answers

What companies run services between Des Moines, IA, USA and Perryville, MO, USA?

There is no direct connection from Des Moines to Perryville. However, you can take the taxi to Des-Moines-Airport-DSM airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, take the train to COLLEGE station, then take the taxi to Perryville. Alternatively, you can take the bus to Kansas City, take the bus to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Perryville.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound