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How to get fromDes Moines to Perryvilleby bus, taxi, car, plane, or train

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There are 6 ways to get from Des Moines to Perryville by bus, taxi, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the taxi from COLLEGE station to Perryvilletaxi taxi
    10h 37m
    $210–301

  2. Drive 393.2 mi

    cheapest
    1. Drive from Des Moines to Perryvillecar car 393.2 mi
    7h 46m
    $72–104

  3. Fly to Lambert–St. Louis International Airport, train, taxi

    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to COLLEGE stationtrain train
    3. Take the taxi from COLLEGE station to Perryvilletaxi taxi
    6h 47m
    $311–1,094

  4. Bus, taxi via Cape Girardeau

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Perryvilletaxi taxi
    11h 59m
    $165–263

  5. Bus, taxi via Carbondale

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Perryvilletaxi taxi
    12h 16m
    $189–313

  6. Fly to Cape Girardeau Municipal Airport, taxi

    1. Fly from Des Moines (DSM) to Cape Girardeau Municipal Airport (CGI)plane plane DSM - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Perryvilletaxi taxi
    6h 4m
    $273–991

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar151Weekly Planes
Duration5h 9mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Perryville, MO, USA?

There is no direct connection from Des Moines to Perryville. However, you can take the bus to St Louis Bus Station, walk to CIVIC CENTER station, take the train to COLLEGE station, then take the taxi to Perryville. Alternatively, you can drive from Des Moines to Perryville in around 7h 46m.

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