There are 6 ways to get from Des Moines to Perryville by plane, train, taxi, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, train, taxi
best- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
- Take the train from LAMBERT AIRPORT TERMINAL #1 station to COLLEGE stationtrain
- Take the taxi from COLLEGE station to Perryvilletaxi
4h 16m$281–994Drive 393.2 mi
cheapest- Drive from Des Moines to Perryvillecar 393.2 mi
7h 46m$72–104Bus, taxi
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Perryvilletaxi
12h 14m$155–285Bus, train, taxi
- Take the bus from Des Moines to Kansas Citybus
- Take the train from Kansas City to St. Louistrain
- Take the taxi from COLLEGE station to Perryvilletaxi
13h 14m$196–321Bus, taxi via Carbondale
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St. Louis to Carbondalebus
- Take the taxi from Carbondale to Perryvilletaxi
12h 44m$185–333Bus, train, taxi via Cape Girardeau
- Take the bus from Des Moines to Kansas Citybus
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Perryvilletaxi
14h 36m$155–275
Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Des Moines to Perryville is to drive which costs $70 - $110 and takes 7h 46m.
The fastest way to get from Des Moines to Perryville is to fly and train and taxi which takes 4h 16m and costs $280 - $1,000.
The distance between Des Moines and Perryville is 366 miles. The road distance is 395.5 miles.
The best way to get from Des Moines to Perryville without a car is to bus and taxi which takes 12h 14m and costs $150 - $290.
It takes approximately 4h 16m to get from Des Moines to Perryville, including transfers.
Yes, the driving distance between Des Moines to Perryville is 395 miles. It takes approximately 7h 46m to drive from Des Moines to Perryville.
There are 22+ hotels available in Perryville.
What companies run services between Des Moines, IA, USA and Perryville, MO, USA?
There is no direct connection from Des Moines to Perryville. However, you can take the taxi to Des-Moines-Airport-DSM airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, take the train to COLLEGE station, then take the taxi to Perryville. Alternatively, you can take the bus to Kansas City, take the bus to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Perryville.
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $120–800
- Phone
- +1 314-982-1400
- transitinformation@metrostlouis.org
- Website
- metrostlouis.org
Train from LAMBERT AIRPORT TERMINAL #1 station to COLLEGE station
- Ave. Duration
- 1h 9m
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- https://www.metrostlouis.org
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $22–27
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from St. Louis to Carbondale
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St. Louis to Carbondale
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $22–35
- Schedules at
- flixbus.com
- Ave. Duration
- 1h 7m
- Estimated price
- $80–170
On Time Cab Service
- Phone
- +1-314-606-9679
- Website
- ontimecabservice.com
Chesterfield Taxi
- Phone
- +1 314-734-0100
- Website
- chesterfieldtaxi.com
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
On Time Cab Service
- Phone
- +1-314-606-9679
- Website
- ontimecabservice.com
Chesterfield Taxi
- Phone
- +1 314-734-0100
- Website
- chesterfieldtaxi.com
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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