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How to get fromDes Moines to Myrtle Beachby plane, bus (Greyhound, Flixbus), bus, train or car

Find Transport to Myrtle Beach

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There are 5 ways to get from Des Moines to Myrtle Beach by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Myrtle Beach (MYR)plane plane DSM - MYR
    5h 11m
    $168–784

  2. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    32h 10m
    $200–430

  3. Bus, train via Raleigh

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Wilmington Cape Fear Public Transitbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    39h 17m
    $323–721

  4. Drive 1,183.1 mi

    1. Drive from Des Moines to Myrtle Beachcar car 1,183.1 mi
    21h 15m
    $216–312

  5. Bus, train

    1. Take the bus from Des Moines to Iowa Citybus bus
    2. Take the bus from Iowa City to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    5. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    40h 45m
    $349–783

Des Moines to Myrtle Beach by bus

Calendar7Weekly Buses
Duration32h 10mAverage Duration
Ticket$200Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Myrtle Beach, SC, USA?

Delta, United Airlines, and American Airlines fly from Des Moines (DSM) to Myrtle Beach (MYR) 5 times a day. Alternatively, you can take a bus from Des Moines to Myrtle Beach Bus Station via Chicago Bus Station and Atlanta Bus Station in around 32h 10m.

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