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How to get fromDes Moines to Mobileby plane, bus, train, bus (Greyhound, Flixbus), car or bus (Flixbus)

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There are 9 ways to get from Des Moines to Mobile by plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mobile Regional Airport

    best
    1. Fly from Des Moines (DSM) to Mobile Regional Airport (MOB)plane plane DSM - MOB
    8h 12m
    $168–821

  2. Bus via New South Memphis

    cheapest
    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Lafayettebus bus
    4. Take the bus from Lafayette to Mobile Bus Stationbus bus
    33h 9m
    $153–458

  3. Bus, train

    1. Take the bus from Des Moines to Champaignbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    30h 27m
    $200–438

  4. Bus

    1. Take the bus from Des Moines to Burlingtonbus bus
    2. Take the bus from Burlington to St Louisbus bus
    3. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    4. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    31h 14m
    $205–447

  5. Drive 955.7 mi

    1. Drive from Des Moines to Mobilecar car 955.7 mi
    18h 13m
    $175–252

  6. Fly to Destin–Fort Walton Beach Airport, bus

    1. Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane plane DSM - VPS
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    5h 19m
    $288–981

  7. Fly to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT)plane plane DSM - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 41m
    $260–1,002

  8. Fly to Pensacola International Airport, bus

    1. Fly from Des Moines (DSM) to Pensacola International Airport (PNS)plane plane DSM - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 42m
    $213–976

  9. Bus, train via Chicago

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    31h 52m
    $222–483

Des Moines to Mobile by bus and train

Calendar7Weekly Services
Duration30h 27mAverage Duration
Ticket$200Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Mobile, AL, USA?

American Airlines, United Airlines, and Delta fly from Des Moines (DSM) to Mobile Regional Airport (MOB) every 4 hours. Alternatively, you can take a bus from Des Moines to Water NB at St Louis St via Burlington, St Louis Bus Station, New Orleans Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 31h 14m.

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