Rome2Rio

How to get fromDes Moines to Mobileby plane, bus (Greyhound, Flixbus), bus, train, car or bus (Flixbus)

Find Transport to Mobile

See all options

There are 8 ways to get from Des Moines to Mobile by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mobile Regional Airport

    best
    1. Fly from Des Moines (DSM) to Mobile Regional Airport (MOB)plane plane DSM - MOB
    8h 30m
    $168–821
  2. Bus

    cheapest
    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to New Orleans Bus Stationbus bus
    4. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    29h 24m
    $126–378
  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    32h 47m
    $204–432
  4. Drive 955.7 mi

    1. Drive from Des Moines to Mobilecar car 955.7 mi
    18h 17m
    $175–252
  5. Fly to Destin–Fort Walton Beach Airport, bus

    1. Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane plane DSM - VPS
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    5h 19m
    $288–981
  6. Fly to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT)plane plane DSM - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 47m
    $260–1,002
  7. Fly to Pensacola International Airport, bus

    1. Fly from Des Moines (DSM) to Pensacola International Airport (PNS)plane plane DSM - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    9h 13m
    $213–976
  8. Bus via Lafayette

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Lafayettebus bus
    4. Take the bus from Lafayette to Mobile Bus Stationbus bus
    33h 9m
    $163–453

Des Moines to Mobile by bus

Calendar4Weekly Buses
Duration29h 24mAverage Duration
Ticket$126Cheapest Price
See schedules

Questions & Answers

What companies run services between Des Moines, IA, USA and Mobile, AL, USA?

American Airlines, Delta, and United Airlines fly from Des Moines (DSM) to Mobile Regional Airport (MOB) every 4 hours. Alternatively, you can take a bus from Des Moines to Water NB at St Louis St via Kansas City, Memphis Bus Station, New Orleans Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 29h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers