There are 7 ways to get from Des Moines to Mobile by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Destin–Fort Walton Beach Airport, bus
best- Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane DSM - VPS
- Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus
5h 21m$278–931Fly to Mobile Regional Airport
cheapest- Fly from Des Moines (DSM) to Mobile Regional Airport (MOB)plane DSM - MOB
7h 35m$158–721Bus, train via Champaign
- Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus
- Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
28h 55m$316–698Bus, train
- Take the bus from Des Moines to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
29h 48m$209–451Drive 955.7 mi
- Drive from Des Moines to Mobilecar 955.7 mi
18h 8m$175–252Fly to Gulfport-Biloxi Regional Airport, bus
- Fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT)plane DSM - GPT
- Take the bus from Gulfport to Mobilebus
7h 25m$250–952Fly to Pensacola International Airport, bus
- Fly from Des Moines (DSM) to Pensacola International Airport (PNS)plane DSM - PNS
- Take the bus from Pensacola Airport to Mobile Bus Stationbus
8h 49m$168–791
Des Moines to Mobile by bus and train
Questions & Answers
The cheapest way to get from Des Moines to Mobile is to drive which costs $170 - $260 and takes 18h 8m.
The fastest way to get from Des Moines to Mobile is to fly and bus which takes 5h 21m and costs $270 - $950.
The distance between Des Moines and Mobile is 987 miles. The road distance is 961.3 miles.
The best way to get from Des Moines to Mobile without a car is to bus and train via Champaign which takes 28h 55m and costs $310 - $700.
It takes approximately 5h 21m to get from Des Moines to Mobile, including transfers.
Yes, the driving distance between Des Moines to Mobile is 961 miles. It takes approximately 18h 8m to drive from Des Moines to Mobile.
There are 180+ hotels available in Mobile.
What companies run services between Des Moines, IA, USA and Mobile, AL, USA?
Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Mobile Regional Airport (MOB) every 3 hours.
- Website
- delta.com
Flights from Des Moines to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $130–700
Flights from Des Moines to Mobile Regional Airport via Atlanta
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $170–850
Flights from Des Moines to Pensacola International Airport via Atlanta
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $140–750
Flights from Des Moines to Pensacola International Airport via Detroit
- Ave. Duration
- 5h 13m
- When
- Saturday
- Estimated price
- $180–850
- Website
- aa.com
Flights from Des Moines to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $160–800
Flights from Des Moines to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 36m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Mobile Regional Airport via Charlotte
- Ave. Duration
- 8h 34m
- When
- Every day
- Estimated price
- $170–850
Flights from Des Moines to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 1m
- When
- Every day
- Estimated price
- $180–900
Flights from Des Moines to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 10h 24m
- When
- Every day
- Estimated price
- $210–1,000
Flights from Des Moines to Pensacola International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $170–800
- Website
- united.com
Flights from Des Moines to Mobile Regional Airport via Houston
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $160–800
Flights from Des Moines to Gulfport-Biloxi Regional Airport via Houston
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $180–900
Flights from Des Moines to Pensacola International Airport via Houston
- Ave. Duration
- 8h 23m
- When
- Every day
- Estimated price
- $170–850
- Website
- southwest.com
Flights from Des Moines to Pensacola International Airport via Chicago Midway
- Ave. Duration
- 7h 17m
- When
- Monday to Wednesday
- Estimated price
- $150–750
- Website
- allegiantair.com
Flights from Des Moines to Destin–Fort Walton Beach Airport
- Ave. Duration
- 2h 18m
- When
- Wednesday and Saturday
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Champaign-Urbana to New Orleans Union Passenger Terminal
- Ave. Duration
- 16h 52m
- Frequency
- Once daily
- Estimated price
- $230–500
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–90
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from McDonald's - Crestview to Love's Travel Stop - Loxley
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $40–130
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–130
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Champaign Intermodal Trans Ctr
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $65–140
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to New Orleans Bus Station
- Ave. Duration
- 16h 50m
- Frequency
- Once daily
- Estimated price
- $110–230
- Website
- https://www.greyhound.com/
Bus from Pensacola Airport to Mobile Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $10–20
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Gulfport to Mobile
- Ave. Duration
- 1h 13m
- Frequency
- Once daily
- Estimated price
- $45–60
- Schedules at
- omnibusexpress.com
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