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How to get fromDes Moines to MobileBy plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 7 ways to get from Des Moines to Mobile by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Destin–Fort Walton Beach Airport, bus

    best
    1. Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane plane DSM - VPS
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    5h 19m
    $258–831
  2. Fly to Mobile Regional Airport

    cheapest
    1. Fly from Des Moines (DSM) to Mobile Regional Airport (MOB)plane plane DSM - MOB
    7h 44m
    $138–671
  3. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    30h 23m
    $283–619
  4. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    30h 59m
    $195–392
  5. Drive 955.7 mi

    1. Drive from Des Moines to Mobilecar car 955.7 mi
    18h 8m
    $175–252
  6. Fly to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT)plane plane DSM - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 52m
    $240–902
  7. Fly to Pensacola International Airport, bus

    1. Fly from Des Moines (DSM) to Pensacola International Airport (PNS)plane plane DSM - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    9h 3m
    $147–640

Des Moines to Mobile by bus and train

Calendar7Weekly Services
Duration30h 23mAverage Duration
Ticket$283Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Mobile, AL, USA?

You can take a bus from Des Moines to Water NB at St Louis St via St Louis Bus Station, New Orleans Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 30h 59m. Alternatively, Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Mobile Regional Airport (MOB) every 3 hours.

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