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How to get fromDes Moines to Mobileby plane, bus, train, or car

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There are 7 ways to get from Des Moines to Mobile by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Destin–Fort Walton Beach Airport, bus

    best
    1. Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane plane DSM - VPS
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    5h 21m
    $278–931
  2. Fly to Mobile Regional Airport

    cheapest
    1. Fly from Des Moines (DSM) to Mobile Regional Airport (MOB)plane plane DSM - MOB
    7h 35m
    $158–721
  3. Bus, train via Champaign

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    28h 55m
    $316–698
  4. Bus, train

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    29h 48m
    $209–451
  5. Drive 955.7 mi

    1. Drive from Des Moines to Mobilecar car 955.7 mi
    18h 8m
    $175–252
  6. Fly to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT)plane plane DSM - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 25m
    $250–952
  7. Fly to Pensacola International Airport, bus

    1. Fly from Des Moines (DSM) to Pensacola International Airport (PNS)plane plane DSM - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 49m
    $168–791

Des Moines to Mobile by bus and train

Calendar7Weekly Services
Duration28h 55mAverage Duration
Ticket$316Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Mobile, AL, USA?

Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Mobile Regional Airport (MOB) every 3 hours.

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